Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GC08M024077 Gene

Subcategory (RNA class) for GC08M024077 Gene

snRNA

Quality Score for this RNA gene is

15

Aliases for GC08M024077 Gene

No Aliases found

ORGUL Members for GC08M024077 Gene

No data available for External Ids for GC08M024077 Gene

Summaries for GC08M024077 Gene

GeneCards Summary for GC08M024077 Gene

GC08M024077 is an RNA Gene, and is affiliated with the snRNA class.

fRNAdb sequence ontologies for GC08M024077 Gene

  • U1_snRNA: U1 is a small nuclear RNA (snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV.

Additional gene information for GC08M024077 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for GC08M024077 Gene

Genomics for GC08M024077 Gene

GeneHancer (GH) Regulatory Elements for GC08M024077 Gene

Promoters and enhancers for GC08M024077 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08J024038 Enhancer 1 Ensembl ENCODE 0.3 +37.5 37494 1.8 SP1 ELF3 MAFK ZNF644 KAT8 RXRA GATAD2A RXRB RCOR2 GABPA GC08M024077 RNU1-148P STC1
GH08J024055 Enhancer 0.5 Ensembl 0.4 +19.0 18957 6 CEBPB JUND EP300 ATF2 MAFF STC1 R3HCC1 GC08M024077 RNU1-148P
GH08J023974 Enhancer 1.2 FANTOM5 Ensembl ENCODE 0.2 +100.6 100595 8.3 SP1 CBFA2T2 PRDM1 ZIC2 POLR2A ZNF341 ZNF140 OSR2 NFIC TCF7L2 STC1 RNU1-148P GC08M024077
GH08J024018 Enhancer 0.8 Ensembl ENCODE 0.2 +59.6 59629 3.9 MAFK ZNF316 CEBPB JUND EP300 STAT3 ZNF514 NFE2L2 MAFF RNU1-148P GC08M024077 STC1
GH08J023990 Enhancer 1 Ensembl ENCODE 0.2 +85.5 85491 2.7 CBFA2T2 SP1 EGR1 SMARCA4 DPF2 HDAC1 POLR2A NRF1 EP300 SOX6 GC08M024077 RNU1-148P STC1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GC08M024077 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GC08M024077 Gene

Genomic Locations for GC08M024077 Gene
chr8:24,076,996-24,077,158
(GRCh38/hg38)
Size:
163 bases
Orientation:
Minus strand

Genomic View for GC08M024077 Gene

Genes around GC08M024077 on UCSC Golden Path with GeneCards custom track

GC08M024077 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GC08M024077 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Cytogenetic band and RefSeq DNA sequence for GC08M024077 Gene

Proteins for GC08M024077 Gene

Post-translational modifications for GC08M024077 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GC08M024077 Gene

Domains & Families for GC08M024077 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GC08M024077 Gene

Function for GC08M024077 Gene

Phenotypes From GWAS Catalog for GC08M024077 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GC08M024077 Gene

Localization for GC08M024077 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GC08M024077 Gene

Pathways & Interactions for GC08M024077 Gene

PathCards logo

SuperPathways for GC08M024077 Gene

No Data Available

Interacting Proteins for GC08M024077 Gene

Gene Ontology (GO) - Biological Process for GC08M024077 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GC08M024077 Gene

Drugs & Compounds for GC08M024077 Gene

No Compound Related Data Available

Transcripts for GC08M024077 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for GC08M024077 Gene

No ASD Table

Relevant External Links for GC08M024077 Gene

GeneLoc Exon Structure for
GC08M024077

No data available for mRNA/cDNA for GC08M024077 Gene

Expression for GC08M024077 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GC08M024077 Gene

Orthologs for GC08M024077 Gene

No data available for Orthologs and Evolution for GC08M024077 Gene

Paralogs for GC08M024077 Gene

No data available for Paralogs for GC08M024077 Gene

Variants for GC08M024077 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for GC08M024077 Gene

Disorders for GC08M024077 Gene

No disorders were found for GC08M024077 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for GC08M024077 Gene

Publications for GC08M024077 Gene

  1. Two functionally distinct steps mediate high affinity binding of U1A protein to U1 hairpin II RNA. (PMID: 11297556) Katsamba PS … Laird-Offringa IA (The Journal of biological chemistry 2001) 1
  2. The uRNA database. (PMID: 9016512) Zwieb C (Nucleic acids research 1997) 1
  3. Crystal structure at 1.92 A resolution of the RNA-binding domain of the U1A spliceosomal protein complexed with an RNA hairpin. (PMID: 7984237) Oubridge C … Nagai K (Nature 1994) 1
  4. Saccharomyces cerevisiae U1 small nuclear RNA secondary structure contains both universal and yeast-specific domains. (PMID: 2405391) Kretzner L … Rosbash M (Proceedings of the National Academy of Sciences of the United States of America 1990) 1

No data available for External Links for GC08M024077 Gene

Products for GC08M024077 Gene

Sources for GC08M024077 Gene

Content
Loading form....