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Aliases for GC01M028003 Gene

Subcategory (RNA class) for GC01M028003 Gene

SRP

Quality Score for this RNA gene is

15

Aliases for GC01M028003 Gene

No Aliases found

ORGUL Members for GC01M028003 Gene

No data available for External Ids for GC01M028003 Gene

Summaries for GC01M028003 Gene

GeneCards Summary for GC01M028003 Gene

GC01M028003 is an RNA Gene, and is affiliated with the SRP RNA class.

fRNAdb sequence ontologies for GC01M028003 Gene

  • Metazoan signal recognition particle RNA: The signal recognition particle (SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. Eukaryotic and archaeal 7S RNAs have very similar secondary structures, as represented by this family. Eight helical elements fold into the Alu and S domains, separated by a long linker region [1,2]. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP [1]. The universally conserved helix which interacts with the SRP54 M domain mediates signal sequence recognition [2,3]. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilises helix 8 for SRP54 binding [1]. The Signal Recognition Particle Database (SRPDB) [4] provides compilations of SRP components, with phylogenetic data and structural illustrations. Many sequences below the threshold for this family are clearly closely related, but are most likely to be SRP RNA derived pseudogenes. The human genome in particular is known to contain a large amount of SRP RNA related sequence, including Alu repeats. While the threshold of this family is set high so as to minimise the number of hits to such regions, it is likely that some remain.

View fRNAdb secondary structures for GC01M028003

Additional gene information for GC01M028003 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for GC01M028003 Gene

Genomics for GC01M028003 Gene

GeneHancer (GH) Regulatory Elements for GC01M028003 Gene

Promoters and enhancers for GC01M028003 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J027991 Enhancer 0.9 FANTOM5 Ensembl ENCODE 0.4 +8.6 8641 3.9 ZNF121 PRDM10 FOSL1 POLR2A REST EYA3 SMPDL3B RPA2 SCARNA1 PPP1R8 RNU6-1245P ATP5IF1 DNAJC8 PTAFR RNU6-176P
GH01J028010 Enhancer 0.3 ENCODE 0.4 -9.0 -9040 1.2 HLF SYTL1 GC01M028003 RN7SL559P EYA3
GH01J028020 Enhancer 0.4 Ensembl 0.4 -19.3 -19306 0.8 PRDM10 ZSCAN4 EYA3 ENSG00000227050 XKR8 SMPDL3B DNAJC8 ATP5IF1 PTAFR SCARNA1 RNU6-1245P PPP1R8
GH01J028028 Enhancer 0.4 Ensembl 0.3 -28.2 -28207 3.8 ZNF121 POLR2A RUNX3 EYA3 SMPDL3B PTAFR PPP1R8 SCARNA1 RNU6-1245P RN7SL559P GC01M028003
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GC01M028003 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GC01M028003 Gene

Genomic Locations for GC01M028003 Gene
chr1:28,001,638-28,001,894
(GRCh38/hg38)
Size:
257 bases
Orientation:
Minus strand

Genomic View for GC01M028003 Gene

Genes around GC01M028003 on UCSC Golden Path with GeneCards custom track

GC01M028003 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GC01M028003 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

ORGUL Member Location for GC01M028003 Gene

ORGUL Member Location for GC01M028003 gene

No data available for Cytogenetic band and RefSeq DNA sequence for GC01M028003 Gene

Proteins for GC01M028003 Gene

Post-translational modifications for GC01M028003 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GC01M028003 Gene

Domains & Families for GC01M028003 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GC01M028003 Gene

Function for GC01M028003 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GC01M028003 Gene

Localization for GC01M028003 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GC01M028003 Gene

Pathways & Interactions for GC01M028003 Gene

PathCards logo

SuperPathways for GC01M028003 Gene

No Data Available

Interacting Proteins for GC01M028003 Gene

Gene Ontology (GO) - Biological Process for GC01M028003 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GC01M028003 Gene

Drugs & Compounds for GC01M028003 Gene

No Compound Related Data Available

Transcripts for GC01M028003 Gene

fRNAdb Secondary structures for GC01M028003 Gene

  • FR043413

Alternative Splicing Database (ASD) splice patterns (SP) for GC01M028003 Gene

No ASD Table

Relevant External Links for GC01M028003 Gene

GeneLoc Exon Structure for
GC01M028003

No data available for mRNA/cDNA for GC01M028003 Gene

Expression for GC01M028003 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GC01M028003 Gene

Orthologs for GC01M028003 Gene

No data available for Orthologs and Evolution for GC01M028003 Gene

Paralogs for GC01M028003 Gene

No data available for Paralogs for GC01M028003 Gene

Variants for GC01M028003 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for GC01M028003 Gene

Disorders for GC01M028003 Gene

No disorders were found for GC01M028003 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for GC01M028003 Gene

Publications for GC01M028003 Gene

  1. SRPDB: Signal Recognition Particle Database. (PMID: 12520023) Rosenblad MA … Samuelsson T (Nucleic acids research 2003) 1
  2. Towards the structure of the mammalian signal recognition particle. (PMID: 11839493) Wild K … Cusack S (Current opinion in structural biology 2002) 1
  3. Prediction of signal recognition particle RNA genes. (PMID: 12140321) Regalia M … Samuelsson T (Nucleic acids research 2002) 1
  4. Structural and energetic analysis of RNA recognition by a universally conserved protein from the signal recognition particle. (PMID: 11243816) Batey RT … Doudna JA (Journal of molecular biology 2001) 1
  5. Crystal structure of the ribonucleoprotein core of the signal recognition particle. (PMID: 10678824) Batey RT … Doudna JA (Science (New York, N.Y.) 2000) 1

No data available for External Links for GC01M028003 Gene

Products for GC01M028003 Gene

Sources for GC01M028003 Gene

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