Free for academic non-profit institutions. Other users need a Commercial license
This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017] See more...
Aliases for GBP5 Gene
Aliases for GBP5 Gene
External Ids for GBP5 Gene
- HGNC: 19895
- NCBI Entrez Gene: 115362
- Ensembl: ENSG00000154451
- OMIM®: 611467
- UniProtKB/Swiss-Prot: Q96PP8
Previous GeneCards Identifiers for GBP5 Gene
- GC01M090208
- GC01M088894
- GC01M089061
- GC01M089193
- GC01M089438
- GC01M089498
- GC01M089724
- GC01M087841
Summaries for GBP5 Gene
-
This gene belongs to the TRAFAC class dynamin-like GTPase superfamily. The encoded protein acts as an activator of NLRP3 inflammasome assembly and has a role in innate immunity and inflammation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2017]
GeneCards Summary for GBP5 Gene
GBP5 (Guanylate Binding Protein 5) is a Protein Coding gene. Diseases associated with GBP5 include Chronic Active Epstein-Barr Virus Infection. Among its related pathways are Innate Immune System and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include identical protein binding and GTPase activity. An important paralog of this gene is GBP3.
UniProtKB/Swiss-Prot Summary for GBP5 Gene
-
As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).
Additional gene information for GBP5 Gene
- HGNC (19895)
- NCBI Entrez Gene (115362)
- Ensembl (ENSG00000154451)
- OMIM® (611467)
- UniProtKB/Swiss-Prot (Q96PP8)
- Open Targets Platform(ENSG00000154451)
- Search for GBP5 at DataMed
- Search for GBP5 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GBP5 Gene
Genomics for GBP5 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GBP5 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GBP5 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GBP5
- Top Transcription factor binding sites by QIAGEN in the GBP5 gene promoter:
-
- AP-2rep
- deltaCREB
- E47
- FOXF2
- Hand1
- Lmo2
- POU2F1
- POU2F1a
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for GBP5 Gene
Latest Assembly
- chr1:89,258,950-89,272,860
- (GRCh38/hg38)
- Size:
- 13,911 bases
- Orientation:
- Minus strand
Previous Assembly
- chr1:89,724,633-89,738,543
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 13,911 bases
- Orientation:
- Minus strand
- chr1:89,724,633-89,738,544
- (GRCh37/hg19 by Ensembl)
- Size:
- 13,912 bases
- Orientation:
- Minus strand
Genomic View for GBP5 Gene
Genes around GBP5 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p22.2 by HGNC
- 1p22.2 by Entrez Gene
- 1p22.2 by Ensembl
GBP5 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GBP5 Gene
Proteins for GBP5 Gene
-
Protein details for GBP5 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96PP8-GBP5_HUMAN
- Recommended name:
- Guanylate-binding protein 5
- Protein Accession:
- Q96PP8
- B2RCE1
- Q86TM5
Protein attributes for GBP5 Gene
- Size:
- 586 amino acids
- Molecular mass:
- 66617 Da
- Quaternary structure:
-
- Homodimer (PubMed:21151871). Heterodimer with other family members, including GBP1, GBP2, GBP3 and GBP4 (PubMed:21151871). Dimerization is nucleotide-dependent; isoform 1 and isoform 2 form dimers when GTP-bound. GDP-bound isoform 2 is monomeric, while isoform 1 remains dimeric (PubMed:20180847). Dimerization regulates subcellular location. May also form tetramers (dimer of dimers) in the presence of GTP (PubMed:20180847). Interacts with NLRP3, possibly in its tetrameric form, and promotes PYCARD/ASC polymerization (PubMed:22461501).
- Miscellaneous:
-
- [Isoform 2]: Antigenic tumor-specific truncated splice form.
Protein Expression for GBP5 Gene
Post-translational modifications for GBP5 Gene
- Isoprenylation is required for proper subcellular location.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for GBP5 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences GBP5 Antibody
- G Biosciences Immunotag™ GBP5 Antibody
- GeneTex Anti-GBP5 antibody [N3C3] and Anti-GBP5 antibody [N1N3]
- Novus Biologicals Antibodies for GBP5
-
Abcam antibodies for GBP5
- Invitrogen Antibodies for GBP5 (AFLGC-GBP5)
- antibodies-online: Show 28 available GBP5 Antibodies ranked by validation data
-
Biorbyt antibodies for GBP5
-
Boster Bio Antibodies for GBP5
-
Custom Antibody ServicesProSci Antibodies for GBP5
-
Santa Cruz Biotechnology (SCBT) Antibodies for GBP5
Protein products for research
- Search Origene for MassSpec and Protein Over-expression Lysates for GBP5
- Origene Custom Protein Services for GBP5
- antibodies-online: Search results for available GBP5 related products ranked by validation data
-
Abcam proteins for GBP5
Assay products for research
- antibodies-online: Search results for available GBP5 related products ranked by validation data
No data available for DME Specific Peptides for GBP5 Gene
Domains & Families for GBP5 Gene
Gene Families for GBP5 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for GBP5 Gene
- InterPro:
- Blocks:
-
- Guanylate-binding protein
- ProtoNet:
Suggested Antigen Peptide Sequences for GBP5 Gene
- GenScript: Design optimal peptide antigens:
-
- Guanine nucleotide-binding protein 5 (GBP5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96PP8UniProtKB/Swiss-Prot:
GBP5_HUMAN :- Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
- Family:
-
- Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
Function for GBP5 Gene
Molecular function for GBP5 Gene
- UniProtKB/Swiss-Prot Function:
- As an activator of NLRP3 inflammasome assembly, plays a role in innate immunity and inflammation. Promotes selective NLRP3 inflammasome assembly in response to microbial and soluble, but not crystalline, agents (PubMed:22461501). Hydrolyzes GTP, but in contrast to other family members, does not produce GMP (PubMed:20180847).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; Evidence={ECO:0000269|PubMed:20180847, ECO:0000269|PubMed:22461501};.
- UniProtKB/Swiss-Prot Induction:
- By IFNG in endothelial cells and in LPS-primed macrophages.
Enzyme Numbers (IUBMB) for GBP5 Gene
Phenotypes From GWAS Catalog for GBP5 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003924 | GTPase activity | IEA,IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 21151871 |
| GO:0005525 | GTP binding | IEA,IBA | 21873635 |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for GBP5 Gene
- MGI mutant phenotypes for GBP5:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for GBP5:
Animal Models for research
-
Taconic Biosciences Mouse Models for GBP5
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GBP5 - Starting at $85 >
- * GBP5 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GBP5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP5
-
Santa Cruz Biotechnology (SCBT) CRISPR for GBP5
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GBP5
- Browse OriGene Inhibitory RNA Products For GBP5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GBP5
Clone products for research
- Applied Biological Materials (abm): Clones for GBP5 - Starting at $45 >
- * GBP5 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GBP5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP5
Cell Lines for research
-
Horizon Cell Lines for GBP5
No data available for Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for GBP5 Gene
Localization for GBP5 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GBP5 Gene
- Cytoplasm. Golgi apparatus membrane. Lipid-anchor.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 5 |
| endoplasmic reticulum | 3 |
| cytosol | 3 |
| mitochondrion | 2 |
| nucleus | 2 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| endosome | 1 |
| lysosome | 1 |
| peroxisome | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | -- |
| GO:0005737 | cytoplasm | IEA,IDA | 17266443 |
| GO:0005794 | Golgi apparatus | IEA,IDA | 17266443 |
| GO:0016020 | membrane | IEA,HDA | 19946888 |
| GO:0031410 | cytoplasmic vesicle | IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for GBP5 Gene
Pathways & Interactions for GBP5 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Interferon gamma signaling | ||
| 2 | NOD-like receptor signaling pathway | ||
| 3 | Cytokine Signaling in Immune system | ||
| 4 | Innate Immune System |
.61
|
|
Pathways by source for GBP5 Gene
4 Reactome pathways for GBP5 Gene
1 KEGG pathway for GBP5 Gene
Interacting Proteins for GBP5 Gene
Selected Interacting proteins:
Q96PP8-GBP5_HUMAN
ENSP00000359488
for GBP5 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for GBP5
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0002376 | immune system process | IEA | -- |
| GO:0006954 | inflammatory response | IEA | -- |
| GO:0032611 | interleukin-1 beta production | IMP | 22461501 |
| GO:0032621 | interleukin-18 production | ISS | -- |
| GO:0034067 | protein localization to Golgi apparatus | IDA | 21151871 |
No data available for SIGNOR curated interactions for GBP5 Gene
Transcripts for GBP5 Gene
mRNA/cDNA for GBP5 Gene
- 3 REFSEQ mRNAs :
- 11 NCBI additional mRNA sequence :
- 5 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000370459 2011 nts (view in UCSC)
- ENST00000443807 4699 nts (view in UCSC)
- ENST00000471171 439 nts (view in UCSC)
- ENST00000481145 4112 nts (view in UCSC)
- ENST00000490568 434 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GBP5 - Starting at $85 >
- * GBP5 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GBP5
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP5
-
Santa Cruz Biotechnology (SCBT) CRISPR for GBP5
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GBP5
- Browse OriGene Inhibitory RNA Products For GBP5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GBP5
Clone products for research
- Applied Biological Materials (abm): Clones for GBP5 - Starting at $45 >
- * GBP5 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GBP5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP5
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||
| SP4: |
Relevant External Links for GBP5 Gene
- GeneLoc Exon Structure for
- GBP5
Expression for GBP5 Gene
mRNA differential expression in normal tissues according to GTEx for GBP5 Gene
This gene is overexpressed in Whole Blood (x20.1) and Spleen (x5.9).
This gene is overexpressed in Spleen (19.4), NK cells (10.4), CD4 Tcells (8.2), and Peripheral blood mononuclear cells (8.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GBP5 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GBP5
SOURCE GeneReport for Unigene cluster for GBP5 Gene:
Hs.513726mRNA Expression by UniProt/SwissProt for GBP5 Gene:
Q96PP8-GBP5_HUMAN
Tissue specificity:
Expressed in peripheral blood monocytes (at protein level).
Evidence on tissue expression from TISSUES for GBP5 Gene
- Nervous system(4.3)
- Blood(3.3)
- Lymph node(2.5)
- Spleen(2.4)
- Intestine(2.4)
Primer products for research
-
OriGene qPCR primer pairs for GBP5
-
OriGene qPCR primer pairs and template standards for GBP5
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for GBP5 Gene
Orthologs for GBP5 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GBP5 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GBP5 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | GBP5 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Gbp5 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Gbp5 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
| Zebrafish (Danio rerio) |
Actinopterygii | CABZ01068209.1 31 |
|
ManyToMany |
- Species where no ortholog for GBP5 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for GBP5 Gene
- ENSEMBL:
- Gene Tree for GBP5 (if available)
- TreeFam:
- Gene Tree for GBP5 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GBP5: view image
Paralogs for GBP5 Gene
Variants for GBP5 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GBP5 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 982609 | Uncertain Significance: Neurodevelopmental disorder | 89,267,076(-) |
G/GAGTC NM_052942.4(GBP5):c.502_505dup (p.Ser169Ter) |
NONSENSE | |
| rs386352305 | Uncertain Significance: not provided | 89,260,720(-) |
G/A NM_052942.4(GBP5):c.1745C>T (p.Pro582Leu) |
MISSENSE | |
| rs61730934 | Benign: not provided | 89,266,511(-) |
T/C NM_052942.4(GBP5):c.703A>G (p.Ile235Val) |
MISSENSE | |
| rs61732483 | Benign: not provided | 89,269,398(-) |
T/A NM_052942.4(GBP5):c.158A>T (p.Tyr53Phe) |
MISSENSE | |
| rs17130763 | - |
p.Glu4Gln |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
58.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.88;
59.11% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GBP5 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- GBP5
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GBP5 Gene
Disorders for GBP5 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| chronic active epstein-barr virus infection |
|
|
Search GBP5 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for GBP5
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for GBP5 Gene
Publications for GBP5 Gene
- Biochemical properties of the human guanylate binding protein 5 and a tumor-specific truncated splice variant. (PMID: 20180847) Wehner M … Herrmann C (The FEBS journal 2010) 3 4 23
- GBP-5 splicing variants: New guanylate-binding proteins with tumor-associated expression and antigenicity. (PMID: 15175044) Fellenberg F … Eichmüller S (The Journal of investigative dermatology 2004) 3 4 23
- GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals. (PMID: 22461501) Shenoy AR … MacMicking JD (Science (New York, N.Y.) 2012) 3 4
- Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner. (PMID: 21151871) Britzen-Laurent N … Stürzl M (PloS one 2010) 3 4
- Oligonucleotide microarray analysis of gene expression profiles followed by real-time reverse-transcriptase polymerase chain reaction assay in chronic active Epstein-Barr virus infection. (PMID: 18260761) Ito Y … Kimura H (The Journal of infectious diseases 2008) 3 23
ExternalLinks
Products for GBP5 Gene
- Custom Antibody ServicesOriGene Antibodies for GBP5
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for GBP5
- Origene Custom Protein Services for GBP5
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GBP5
- Browse OriGene Inhibitory RNA Products For GBP5
- OriGene qPCR primer pairs for GBP5
- OriGene qPCR primer pairs and template standards for GBP5
- OriGene CRISPR knockouts for GBP5
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For GBP5
- Sino Biological Human cDNA Clone for GBP5
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for GBP5
- Novus Biologicals proteins and lysates for GBP5
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for GBP5
- Abcam proteins for GBP5
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for GBP5
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for GBP5 (AFLGC-GBP5)
- VectorBuilder Custom and pre-made DNA vectors for GBP5 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for GBP5 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for GBP5 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for GBP5 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for GBP5
- antibodies-online: Show 28 available GBP5 Antibodies ranked by validation data
- antibodies-online: Search results for available GBP5 related products ranked by validation data
- antibodies-online: Search results for available GBP5 related products ranked by validation data
- Santa Cruz Biotechnology (SCBT) Antibodies for GBP5
- Search Santa Cruz Biotechnology (SCBT) for GBP5 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for GBP5
- Custom Antibody ServicesProSci Antibodies for GBP5
- Search for GBP5 Proteins at ProSci
- Horizon Cell Lines for GBP5
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP5
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP5
- Search GeneCopoeia for miRNA 3'UTR Target clone products for GBP5
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GBP5
- Boster Bio Antibodies for GBP5
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for GBP5
Sources for GBP5 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB