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Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008] See more...
Aliases for GBP4 Gene
Aliases for GBP4 Gene
External Ids for GBP4 Gene
- HGNC: 20480
- NCBI Entrez Gene: 115361
- Ensembl: ENSG00000162654
- OMIM®: 612466
- UniProtKB/Swiss-Prot: Q96PP9
Previous GeneCards Identifiers for GBP4 Gene
- GC01M090127
- GC01M088817
- GC01M088984
- GC01M089114
- GC01M089359
- GC01M089420
- GC01M089646
- GC01M087764
Summaries for GBP4 Gene
-
Guanylate-binding proteins, such as GBP4, are induced by interferon and hydrolyze GTP to both GDP and GMP (Vestal, 2005 [PubMed 16108726]).[supplied by OMIM, Dec 2008]
GeneCards Summary for GBP4 Gene
GBP4 (Guanylate Binding Protein 4) is a Protein Coding gene. Diseases associated with GBP4 include High Pressure Neurological Syndrome and Osteopetrosis, Autosomal Dominant 2. Among its related pathways are Innate Immune System and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GBP7.
UniProtKB/Swiss-Prot Summary for GBP4 Gene
-
Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity).
Additional gene information for GBP4 Gene
- HGNC (20480)
- NCBI Entrez Gene (115361)
- Ensembl (ENSG00000162654)
- OMIM® (612466)
- UniProtKB/Swiss-Prot (Q96PP9)
- Open Targets Platform(ENSG00000162654)
- Search for GBP4 at DataMed
- Search for GBP4 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GBP4 Gene
Genomics for GBP4 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GBP4 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GBP4 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GBP4
- Top Transcription factor binding sites by QIAGEN in the GBP4 gene promoter:
-
- En-1
- GATA-2
- LCR-F1
- NF-AT1
- NF-AT2
- NF-AT3
- NF-AT4
- SRF
- SRF (504 AA)
- STAT1
Genomic Locations for GBP4 Gene
Latest Assembly
- chr1:89,181,144-89,198,942
- (GRCh38/hg38)
- Size:
- 17,799 bases
- Orientation:
- Minus strand
Previous Assembly
- chr1:89,646,827-89,664,625
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 17,799 bases
- Orientation:
- Minus strand
- chr1:89,646,831-89,664,615
- (GRCh37/hg19 by Ensembl)
- Size:
- 17,785 bases
- Orientation:
- Minus strand
Genomic View for GBP4 Gene
Genes around GBP4 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p22.2 by HGNC
- 1p22.2 by Entrez Gene
- 1p22.2 by Ensembl
GBP4 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GBP4 Gene
Proteins for GBP4 Gene
-
Protein details for GBP4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96PP9-GBP4_HUMAN
- Recommended name:
- Guanylate-binding protein 4
- Protein Accession:
- Q96PP9
- B2R630
- Q05D63
- Q6NSL0
- Q86T99
Protein attributes for GBP4 Gene
- Size:
- 640 amino acids
- Molecular mass:
- 73165 Da
- Quaternary structure:
-
- Heterodimer with other family members, including GBP1, GBP2 and GBP5 (PubMed:21151871). Dimerization regulates subcellular location.
- SequenceCaution:
-
- Sequence=BAC85144.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
Protein Expression for GBP4 Gene
Post-translational modifications for GBP4 Gene
Other Protein References for GBP4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences GBP4 / Mpa2 Antibody
- G Biosciences Immunotag™ GBP4 Antibody
-
Custom Antibody ServicesOriGene Antibodies for GBP4
- Novus Biologicals Antibodies for GBP4
-
Abcam antibodies for GBP4
- Invitrogen Antibodies for GBP4 (AFLGC-GBP4)
-
Biorbyt antibodies for GBP4
-
Custom Antibody ServicesProSci Antibodies for GBP4
-
Santa Cruz Biotechnology (SCBT) Antibodies for GBP4
Protein products for research
-
OriGene Purified Proteins for GBP4
- Search Origene for MassSpec and Protein Over-expression Lysates for GBP4
- Origene Custom Protein Services for GBP4
- antibodies-online: Show 9 available GBP4 Proteins ranked by validation data
- Compare Top GBP4 Proteins
-
Quality Products:
-
Abcam proteins for GBP4
No data available for DME Specific Peptides for GBP4 Gene
Domains & Families for GBP4 Gene
Gene Families for GBP4 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Plasma proteins
- Predicted intracellular proteins
Protein Domains for GBP4 Gene
- InterPro:
- Blocks:
-
- Guanylate-binding protein
- ProtoNet:
Suggested Antigen Peptide Sequences for GBP4 Gene
- GenScript: Design optimal peptide antigens:
-
- Guanylate binding protein 4, isoform CRA_a (D3DT27_HUMAN)
- Guanine nucleotide-binding protein 4 (GBP4_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q96PP9UniProtKB/Swiss-Prot:
GBP4_HUMAN :- Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
- Family:
-
- Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
Function for GBP4 Gene
Molecular function for GBP4 Gene
- UniProtKB/Swiss-Prot Function:
- Binds GTP, GDP and GMP. Hydrolyzes GTP very efficiently; GDP rather than GMP is the major reaction product. Plays a role in erythroid differentiation (By similarity).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; Evidence={ECO:0000250|UniProtKB:P32455};.
- UniProtKB/Swiss-Prot Induction:
- By IFNG during macrophage activation.
Enzyme Numbers (IUBMB) for GBP4 Gene
Phenotypes From GWAS Catalog for GBP4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003924 | GTPase activity | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 21151871 |
| GO:0005525 | GTP binding | IBA | 21873635 |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for GBP4 Gene
- MGI mutant phenotypes for GBP4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for GBP4:
-
- Increased vaccinia virus (VACV) infection
- no effect
- Decreased vaccinia virus (VACV) infection
- Decreased viability
- Decreased NF-kappaB reporter expression
- Decreased viability after Maraba virus infection
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Synthetic lethal with imatinib mesylate
- Downregulation of Wnt pathway after Wnt3A stimulation
Animal Models for GBP4 Gene
- MGI Knock Outs for GBP4:
-
- Gbp3 Gbp3<tm1b(KOMP)Wtsi>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GBP4 - Starting at $85 >
- * GBP4 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GBP4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP4
-
Santa Cruz Biotechnology (SCBT) CRISPR for GBP4
miRNA for GBP4 Gene
- miRTarBase miRNAs that target GBP4
-
- hsa-miR-92a-3p (MIRT049565)
- hsa-miR-3143 (MIRT498324)
- hsa-miR-335-5p (MIRT498325)
- hsa-miR-543 (MIRT498326)
- hsa-miR-4279 (MIRT635458)
- hsa-miR-6778-3p (MIRT635459)
- hsa-miR-1976 (MIRT635460)
- hsa-miR-3653-5p (MIRT635461)
- hsa-miR-6747-3p (MIRT635462)
- hsa-miR-6727-3p (MIRT635463)
- hsa-miR-4722-3p (MIRT635464)
- hsa-miR-122-3p (MIRT635465)
- hsa-miR-640 (MIRT671897)
- hsa-miR-378a-5p (MIRT671898)
- hsa-miR-6821-3p (MIRT671899)
- hsa-miR-4638-5p (MIRT671900)
- hsa-miR-6790-3p (MIRT671901)
- hsa-miR-1307-3p (MIRT671902)
- hsa-miR-7107-5p (MIRT671903)
- hsa-miR-1234-3p (MIRT671904)
- hsa-miR-6827-3p (MIRT671905)
- hsa-miR-340-3p (MIRT671906)
- hsa-miR-4752 (MIRT717882)
- hsa-miR-6833-5p (MIRT717883)
- hsa-miR-6874-5p (MIRT717884)
- hsa-miR-7847-3p (MIRT717885)
- hsa-miR-6500-5p (MIRT717886)
- hsa-miR-4633-3p (MIRT717887)
- hsa-miR-558 (MIRT717888)
- hsa-miR-942-5p (MIRT717889)
- hsa-miR-1236-3p (MIRT717890)
- hsa-miR-6515-3p (MIRT717891)
- hsa-miR-6758-3p (MIRT717892)
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GBP4
- Browse OriGene Inhibitory RNA Products For GBP4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GBP4
Clone products for research
- Applied Biological Materials (abm): Clones for GBP4 - Starting at $45 >
- * GBP4 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GBP4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP4
Cell Lines for research
-
Horizon Cell Lines for GBP4
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GBP4 Gene
Localization for GBP4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GBP4 Gene
- Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Golgi apparatus membrane. Note=Heterodimers with GBP1, GBP2 and GBP5 localize in the compartment of the prenylated GBPs: with GBP1 in a vesicle-like compartment, with GBP2, around the nucleus and with GBP-5, at the Golgi apparatus. {ECO:0000269 PubMed:21151871}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| plasma membrane | 4 |
| golgi apparatus | 4 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| lysosome | 1 |
| peroxisome | 0 |
- Golgi apparatus (3)
- Plasma membrane (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | -- |
| GO:0005634 | nucleus | IEA,IDA | 17266443 |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0005794 | Golgi apparatus | IEA,IDA | -- |
| GO:0005829 | cytosol | IDA | 21151871 |
Pathways & Interactions for GBP4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Interferon gamma signaling | ||
| 2 | NOD-like receptor signaling pathway | ||
| 3 | Cytokine Signaling in Immune system | ||
| 4 | Innate Immune System |
.61
|
|
Pathways by source for GBP4 Gene
4 Reactome pathways for GBP4 Gene
1 KEGG pathway for GBP4 Gene
Interacting Proteins for GBP4 Gene
GPS-Prot Interaction Network for GBP4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0042832 | defense response to protozoan | IBA | 21873635 |
| GO:0050830 | defense response to Gram-positive bacterium | IBA | 21873635 |
| GO:0071346 | cellular response to interferon-gamma | IBA,IEP | 17266443 |
No data available for SIGNOR curated interactions for GBP4 Gene
Drugs & Compounds for GBP4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for GBP4 Gene
mRNA/cDNA for GBP4 Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000355754 6141 nts (view in UCSC)
- ENST00000471938 768 nts (view in UCSC)
- ENST00000481397 457 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GBP4 - Starting at $85 >
- * GBP4 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GBP4
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP4
-
Santa Cruz Biotechnology (SCBT) CRISPR for GBP4
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GBP4
- Browse OriGene Inhibitory RNA Products For GBP4
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GBP4
Clone products for research
- Applied Biological Materials (abm): Clones for GBP4 - Starting at $45 >
- * GBP4 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GBP4
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP4
Relevant External Links for GBP4 Gene
- GeneLoc Exon Structure for
- GBP4
Expression for GBP4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
This gene is overexpressed in Lymph node (20.7) and Heart (12.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GBP4 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GBP4
SOURCE GeneReport for Unigene cluster for GBP4 Gene:
Hs.409925Evidence on tissue expression from TISSUES for GBP4 Gene
- Spleen(4.4)
- Nervous system(4.3)
- Lymph node(2.2)
- Lung(2.1)
Primer products for research
-
OriGene qPCR primer pairs for GBP4
-
OriGene qPCR primer pairs and template standards for GBP4
Gene Expression Assays for research
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GBP4 Gene
Orthologs for GBP4 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GBP4 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Gbp3 30 17 31 |
|
ManyToMany | |
| Gbp7 31 |
|
ManyToMany | |||
| Rat (Rattus norvegicus) |
Mammalia | Gbp4 30 |
|
||
| Cow (Bos Taurus) |
Mammalia | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| BT.37579 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| GBP4 31 |
|
ManyToMany | |||
| GBP6 31 |
|
ManyToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany | |||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| Chicken (Gallus gallus) |
Aves | -- 31 |
|
ManyToMany | |
| Lizard (Anolis carolinensis) |
Reptilia | -- 31 |
|
ManyToMany | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | LOC100496810 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | gbp2 31 |
|
ManyToMany |
- Species where no ortholog for GBP4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for GBP4 Gene
- ENSEMBL:
- Gene Tree for GBP4 (if available)
- TreeFam:
- Gene Tree for GBP4 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GBP4: view image
Paralogs for GBP4 Gene
Variants for GBP4 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GBP4 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs61738489 | Benign: not provided | 89,191,291(-) |
G/A NM_052941.5(GBP4):c.886C>T (p.Leu296=) |
SYNONYMOUS | |
| rs1142886 | - |
p.Met542Ile |
|||
| rs1142888 | - |
p.Met545Leu |
|||
| rs1142889 | - |
p.Met545Ile |
|||
| rs1142890 | - |
p.Glu546Lys |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
96.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.04;
60.55% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GBP4 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GBP4 Gene
Disorders for GBP4 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| high pressure neurological syndrome |
|
|
| osteopetrosis, autosomal dominant 2 |
|
|
Search GBP4 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for GBP4
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for GBP4 Gene
Publications for GBP4 Gene
- Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner. (PMID: 21151871) Britzen-Laurent N … Stürzl M (PloS one 2010) 3 4
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 41
- Unique features of different members of the human guanylate-binding protein family. (PMID: 17266443) Tripal P … Stürzl M (Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2007) 3 4
- In silico genomic analysis of the human and murine guanylate-binding protein (GBP) gene clusters. (PMID: 16689661) Olszewski MA … Vestal DJ (Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2006) 2 3
- Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei. (PMID: 30021884) Fasci D … Heck AJR (Molecular & cellular proteomics : MCP 2018) 3
ExternalLinks
Products for GBP4 Gene
- Custom Antibody ServicesOriGene Antibodies for GBP4
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- antibodies-online: Show 36 available GBP4 Antibodies ranked by validation data
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- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for GBP4
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- Biorbyt antibodies for GBP4
Sources for GBP4 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB