Aliases for GBP3 Gene
External Ids for GBP3 Gene
Previous GeneCards Identifiers for GBP3 Gene
This gene encodes a member of the guanylate-binding protein (GBP) family. GBPs specifically bind guanine nucleotides (GMP, GDP, and GTP) and contain two of the three consensus motifs found in typical GTP-binding proteins. The encoded protein interacts with a member of the germinal center kinase family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2017]
GeneCards Summary for GBP3 Gene
GBP3 (Guanylate Binding Protein 3) is a Protein Coding gene. Diseases associated with GBP3 include Retinitis Pigmentosa 7. Among its related pathways are Innate Immune System and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GBP1.
UniProtKB/Swiss-Prot Summary for GBP3 Gene
Exhibits antiviral activity against influenza virus.