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This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013] See more...
Aliases for GBP2 Gene
Aliases for GBP2 Gene
External Ids for GBP2 Gene
- HGNC: 4183
- NCBI Entrez Gene: 2634
- Ensembl: ENSG00000162645
- OMIM®: 600412
- UniProtKB/Swiss-Prot: P32456
Previous GeneCards Identifiers for GBP2 Gene
- GC01M090050
- GC01M088741
- GC01M088908
- GC01M089038
- GC01M089283
- GC01M089344
- GC01M089345
- GC01M089571
- GC01M087690
Summaries for GBP2 Gene
-
This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas. [provided by RefSeq, Jul 2013]
GeneCards Summary for GBP2 Gene
GBP2 (Guanylate Binding Protein 2) is a Protein Coding gene. Among its related pathways are Innate Immune System and Interferon gamma signaling. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GBP3.
UniProtKB/Swiss-Prot Summary for GBP2 Gene
-
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832). Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).
Additional gene information for GBP2 Gene
- HGNC (4183)
- NCBI Entrez Gene (2634)
- Ensembl (ENSG00000162645)
- OMIM® (600412)
- UniProtKB/Swiss-Prot (P32456)
- Open Targets Platform(ENSG00000162645)
- Search for GBP2 at DataMed
- Search for GBP2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GBP2 Gene
Genomics for GBP2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GBP2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GBP2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GBP2
- Top Transcription factor binding sites by QIAGEN in the GBP2 gene promoter:
-
- AML1a
Genomic Locations for GBP2 Gene
Latest Assembly
- chr1:89,106,132-89,150,456
- (GRCh38/hg38)
- Size:
- 44,325 bases
- Orientation:
- Minus strand
Previous Assembly
- chr1:89,571,815-89,591,797
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 19,983 bases
- Orientation:
- Minus strand
- chr1:89,571,815-89,616,139
- (GRCh37/hg19 by Ensembl)
- Size:
- 44,325 bases
- Orientation:
- Minus strand
Genomic View for GBP2 Gene
Genes around GBP2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p22.2 by HGNC
- 1p22.2 by Entrez Gene
- 1p22.2 by Ensembl
GBP2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GBP2 Gene
Proteins for GBP2 Gene
-
Protein details for GBP2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P32456-GBP2_HUMAN
- Recommended name:
- Guanylate-binding protein 2
- Protein Accession:
- P32456
- Q6GPH0
- Q6IAU2
- Q86TB0
Protein attributes for GBP2 Gene
- Size:
- 591 amino acids
- Molecular mass:
- 67209 Da
- Quaternary structure:
-
- Homodimer; homodimerization occurs upon GTP-binding and is required for the association with membranous structures. Heterodimer with other family members, including GBP1, GBP3, GBP4 and GBP5.
Protein Expression for GBP2 Gene
Post-translational modifications for GBP2 Gene
- Isoprenylation is required for proper subcellular location.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for GBP2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences GBP2 Monoclonal Antibody
- G Biosciences Immunotag™ GBP2 Antibody
- HUABIO GBP2 Antibody (ER2001-12)
- BioLegend FBXL5 Antibody (672604) and FBXL5 Antibody (672603)
-
Custom Antibody ServicesOriGene Antibodies for GBP2
- Novus Biologicals Antibodies for GBP2
-
Abcam antibodies for GBP2
- Invitrogen Antibodies for GBP2 (AFLGC-GBP2)
-
Boster Bio Antibodies for GBP2
-
Custom Antibody ServicesProSci Antibodies for GBP2
-
Santa Cruz Biotechnology (SCBT) Antibodies for GBP2
- Sino Biological Antibodies for GBP2
Protein products for research
-
OriGene Purified Proteins for GBP2
- Search Origene for MassSpec and Protein Over-expression Lysates for GBP2
- Origene Custom Protein Services for GBP2
- Sino Biological Recombinant Proteins for GBP2
- Sino Biological Cell Lysates for GBP2
-
Abcam proteins for GBP2
Assay products for research
- antibodies-online: Search results for available GBP2 related products ranked by validation data
No data available for DME Specific Peptides for GBP2 Gene
Domains & Families for GBP2 Gene
Gene Families for GBP2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for GBP2 Gene
- InterPro:
- Blocks:
-
- Guanylate-binding protein
- ProtoNet:
Suggested Antigen Peptide Sequences for GBP2 Gene
- GenScript: Design optimal peptide antigens:
-
- Guanine nucleotide-binding protein 2 (GBP2_HUMAN)
- GBP2 protein (Q8TCE5_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P32456UniProtKB/Swiss-Prot:
GBP2_HUMAN :- Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
- Family:
-
- Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3 GTPase family. GB1 subfamily.
Function for GBP2 Gene
Molecular function for GBP2 Gene
- UniProtKB/Swiss-Prot Function:
- Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP (PubMed:8706832). Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes (By similarity).
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565, ChEBI:CHEBI:43474, ChEBI:CHEBI:58189; Evidence={ECO:0000269|PubMed:8706832};.
- UniProtKB/Swiss-Prot Induction:
- By IFNG/IFN-gamma during macrophage activation, and by TNF and IL1B.
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- Kinetic parameters: KM=313 uM for GTP {ECO:0000269|PubMed:8706832};
Enzyme Numbers (IUBMB) for GBP2 Gene
Phenotypes From GWAS Catalog for GBP2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003924 | GTPase activity | IBA | 21873635 |
| GO:0005515 | protein binding | IPI | 18985028 |
| GO:0005525 | GTP binding | TAS,IBA | 21873635 |
| GO:0016787 | hydrolase activity | IEA | -- |
Phenotypes for GBP2 Gene
- MGI mutant phenotypes for GBP2:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for GBP2:
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GBP2 - Starting at $85 >
- * GBP2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GBP2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for GBP2
miRNA for GBP2 Gene
- miRTarBase miRNAs that target GBP2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GBP2
- Browse OriGene Inhibitory RNA Products For GBP2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GBP2
Clone products for research
- Applied Biological Materials (abm): Clones for GBP2 - Starting at $45 >
- * GBP2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GBP2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP2
Cell Lines for research
-
Horizon Cell Lines for GBP2
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GBP2 Gene
Localization for GBP2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GBP2 Gene
- Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane. Lipid-anchor. Note=GBP2-GBP5 dimers localize to the Golgi apparatus. {ECO:0000269 PubMed:21151871}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 5 |
| golgi apparatus | 5 |
| cytoskeleton | 4 |
| plasma membrane | 2 |
| extracellular | 2 |
| mitochondrion | 2 |
| endoplasmic reticulum | 2 |
| endosome | 2 |
| lysosome | 2 |
| peroxisome | 1 |
- Cytosol (3)
- Nucleoplasm (1)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | -- |
| GO:0005634 | nucleus | IDA | 17266443 |
| GO:0005654 | nucleoplasm | IDA | -- |
| GO:0005737 | cytoplasm | IEA,IDA | 21151871 |
| GO:0005794 | Golgi apparatus | IEA,IDA | 17266443 |
Pathways & Interactions for GBP2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Interferon gamma signaling | ||
| 2 | NOD-like receptor signaling pathway | ||
| 3 | Cytokine Signaling in Immune system | ||
| 4 | Innate Immune System |
.61
|
|
| 5 | Immune response IFN alpha/beta signaling pathway | ||
Pathways by source for GBP2 Gene
5 Reactome pathways for GBP2 Gene
1 KEGG pathway for GBP2 Gene
Interacting Proteins for GBP2 Gene
Selected Interacting proteins:
P32456-GBP2_HUMAN
ENSP00000359497
for GBP2 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for GBP2
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006955 | immune response | TAS | 1715024 |
| GO:0034504 | protein localization to nucleus | IDA | 21151871 |
| GO:0042832 | defense response to protozoan | IBA | 21873635 |
| GO:0050830 | defense response to Gram-positive bacterium | IBA | 21873635 |
| GO:0060333 | interferon-gamma-mediated signaling pathway | TAS | -- |
No data available for SIGNOR curated interactions for GBP2 Gene
Drugs & Compounds for GBP2 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Guanosine triphosphate | Experimental | Pharma | 0 |
Transcripts for GBP2 Gene
mRNA/cDNA for GBP2 Gene
- 1 REFSEQ mRNAs :
- 17 NCBI additional mRNA sequence :
- 4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000370466 4088 nts (view in UCSC)
- ENST00000463660 3461 nts (view in UCSC)
- ENST00000464839 3687 nts (view in UCSC)
- ENST00000493802 794 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GBP2 - Starting at $85 >
- * GBP2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GBP2
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP2
-
Santa Cruz Biotechnology (SCBT) CRISPR for GBP2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GBP2
- Browse OriGene Inhibitory RNA Products For GBP2
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GBP2
Clone products for research
- Applied Biological Materials (abm): Clones for GBP2 - Starting at $45 >
- * GBP2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GBP2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP2
Relevant External Links for GBP2 Gene
- GeneLoc Exon Structure for
- GBP2
Expression for GBP2 Gene
mRNA differential expression in normal tissues according to GTEx for GBP2 Gene
This gene is overexpressed in Whole Blood (x9.1).
This gene is overexpressed in Spleen (19.0), Lymph node (7.0), and Peripheral blood mononuclear cells (6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GBP2 Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GBP2
SOURCE GeneReport for Unigene cluster for GBP2 Gene:
Hs.386567Evidence on tissue expression from TISSUES for GBP2 Gene
- Nervous system(4.7)
- Skin(4.5)
- Blood(3.4)
- Spleen(3)
- Intestine(2.9)
- Lymph node(2.8)
- Lung(2.6)
- Liver(2.3)
- Muscle(2.3)
- Heart(2.3)
- Kidney(2.2)
- Bone marrow(2.1)
Primer products for research
-
OriGene qPCR primer pairs for GBP2
-
OriGene qPCR primer pairs and template standards for GBP2
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GBP2 Gene
Orthologs for GBP2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GBP2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GBP2 30 |
|
||
| -- 31 |
|
OneToMany | |||
| -- 31 |
|
OneToMany | |||
| Rat (Rattus norvegicus) |
Mammalia | Gbp2 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Gbp2 30 17 31 |
|
OneToMany | |
| Gbp2b 31 |
|
OneToMany | |||
| Oppossum (Monodelphis domestica) |
Mammalia | -- 31 |
|
ManyToMany | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
ManyToMany | |
| Chicken (Gallus gallus) |
Aves | GBP 30 |
|
||
| -- 31 |
|
ManyToMany | |||
| African clawed frog (Xenopus laevis) |
Amphibia | LOC398692 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | si:ch211-209n20.1 31 |
|
ManyToMany |
- Species where no ortholog for GBP2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- Dog (Canis familiaris)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Lizard (Anolis carolinensis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for GBP2 Gene
- ENSEMBL:
- Gene Tree for GBP2 (if available)
- TreeFam:
- Gene Tree for GBP2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GBP2: view image
Paralogs for GBP2 Gene
Variants for GBP2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GBP2 Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs386352304 | Uncertain Significance: not provided | 89,120,286(-) |
A/C NM_004120.5(GBP2):c.321T>G (p.Gly107=) |
SYNONYMOUS | |
| rs1803632 | - |
p.Pro285Ala |
|||
| rs2230336 | - |
p.Ser281Pro |
|||
| rs2230338 | - |
p.Ser303Gly |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
56.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.45;
28.36% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GBP2 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GBP2 Gene
Disorders for GBP2 Gene
Additional Disease Information for GBP2
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for GBP2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GBP2 Gene
Publications for GBP2 Gene
- Interferon-induced guanylate-binding proteins lack an N(T)KXD consensus motif and bind GMP in addition to GDP and GTP. (PMID: 1715024) Cheng YS … Staeheli P (Molecular and cellular biology 1991) 2 3 4
- Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner. (PMID: 21151871) Britzen-Laurent N … Stürzl M (PloS one 2010) 3 4
- Guanylate-binding protein 2 mRNA in peripheral blood leukocytes of liver transplant recipients as a marker for acute cellular rejection. (PMID: 19912588) Kobayashi S … Mori M (Transplant international : official journal of the European Society for Organ Transplantation 2010) 3 23
- Interferon-inducible guanylate binding protein (GBP)-2: a novel p53-regulated tumor marker in esophageal squamous cell carcinomas. (PMID: 19003964) Guimarães DP … Hainaut P (International journal of cancer 2009) 3 23
- Unique features of different members of the human guanylate-binding protein family. (PMID: 17266443) Tripal P … Stürzl M (Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2007) 3 4
ExternalLinks
Products for GBP2 Gene
- Custom Antibody ServicesOriGene Antibodies for GBP2
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for GBP2
- Search Origene for MassSpec and Protein Over-expression Lysates for GBP2
- Origene Custom Protein Services for GBP2
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- Browse OriGene Inhibitory RNA Products For GBP2
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- OriGene qPCR primer pairs and template standards for GBP2
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- Sino Biological Antibodies for GBP2
- Browse Sino Biological Assays
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- Browse Antibodies
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for GBP2
- Novus Biologicals proteins and lysates for GBP2
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for GBP2
- Abcam proteins for GBP2
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for GBP2 (AFLGC-GBP2)
- VectorBuilder Custom and pre-made DNA vectors for GBP2 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for GBP2 (ie. lentivirus, AAV, adenovirus)
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- VectorBuilder Virus packaging for GBP2 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for GBP2
- antibodies-online: Show 42 available GBP2 Antibodies ranked by validation data
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- antibodies-online: Search results for available GBP2 related products ranked by validation data
- antibodies-online: Show 13 available GBP2 Proteins ranked by validation data
- Compare Top GBP2 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for GBP2
- Search Santa Cruz Biotechnology (SCBT) for GBP2 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for GBP2
- Custom Antibody ServicesProSci Antibodies for GBP2
- Search for GBP2 Proteins at ProSci
- Horizon Cell Lines for GBP2
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GBP2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GBP2
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- Boster Bio Antibodies for GBP2
- Browse Boster Bio ELISA Kits
Sources for GBP2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB