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Aliases for GATA2 Gene

Aliases for GATA2 Gene

  • GATA Binding Protein 2 2 3 5
  • GATA-Binding Protein 2 2 4
  • Endothelial Transcription Factor GATA-2 3
  • MONOMAC 3
  • IMD21 3
  • NFE1B 3
  • DCML 3

External Ids for GATA2 Gene

Previous GeneCards Identifiers for GATA2 Gene

  • GC03U990039
  • GC03M129481
  • GC03M129519
  • GC03M129680
  • GC03M128198
  • GC03M125582

Summaries for GATA2 Gene

Entrez Gene Summary for GATA2 Gene

  • This gene encodes a member of the GATA family of zinc-finger transcription factors that are named for the consensus nucleotide sequence they bind in the promoter regions of target genes. The encoded protein plays an essential role in regulating transcription of genes involved in the development and proliferation of hematopoietic and endocrine cell lineages. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

CIViC summary for GATA2 Gene

  • GATA2 is a transcription factor involved in stem cell maintenance with key roles in hematopoietic development. GATA2 mutations are associated with a variety of inherited and acquired immune disorders including myelodysplastic syndrome and acute myeloid leukemia. In addition to a role in hematopoiesis, the maintenance GATA2 expression has been implicated as a requirement in KRAS-driven non-small cell lung cancer. Preclinical models have indicated therapeutic benefit from targeting GATA2-mediated pathways in the context of KRAS-driven NSCLC.

GeneCards Summary for GATA2 Gene

GATA2 (GATA Binding Protein 2) is a Protein Coding gene. Diseases associated with GATA2 include Immunodeficiency 21 and Lymphedema, Primary, With Myelodysplasia. Among its related pathways are Adipogenesis and G-AlphaQ Signaling. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and chromatin binding. An important paralog of this gene is GATA3.

UniProtKB/Swiss-Prot for GATA2 Gene

  • Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5-AGATAG-3.

Gene Wiki entry for GATA2 Gene

Additional gene information for GATA2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GATA2 Gene

Genomics for GATA2 Gene

GeneHancer (GH) Regulatory Elements for GATA2 Gene

Promoters and enhancers for GATA2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J128481 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 650.4 +5.4 5438 11.8 HDGF PKNOX1 SMAD1 ZFP64 ARID4B SIN3A DMAP1 POLR2B ZNF143 FOS GATA2-AS1 GATA2 ISY1 TPRA1 DNAJB8 RPL32P3 DNAJB8-AS1 H1FX ENSG00000244932 TMED10P2
GH03J128407 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 27.5 +80.1 80060 10.7 HDGF PKNOX1 SMAD1 ARNT POLR2B ZNF766 FOS DEK REST SMARCB1 GATA2 DNAJB8 ENSG00000244932 RPL32P3 H1FX-AS1 TPRA1 DNAJB8-AS1 EFCC1 EEFSEC LINC01565
GH03J128079 Enhancer 1.4 FANTOM5 ENCODE dbSUPER 22.7 +412.4 412374 3.5 HDAC1 HDGF THRB RAD21 RARA YY1 ZNF366 FOS ATF7 RXRA GATA2 TPRA1 EFCC1 SEC61A1 EEFSEC DNAJB8 RUVBL1-AS1 PIR39032 RUVBL1
GH03J128074 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 15.7 +416.4 416393 3.7 PKNOX1 SMAD1 ATF1 SIN3A IRF4 ZNF766 GATA2 ARID2 ZNF207 ZNF143 RNU2-37P RUVBL1-AS1 GC03M128076 GATA2 SEC61A1 RUVBL1 DNAJB8 PIR39032
GH03J128496 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 17.8 -4.1 -4073 2.2 HDGF SIN3A ZNF48 YY1 TCF12 POLR2B ZNF213 GATA2 ARID2 ZNF143 DNAJB8 GATA2 DNAJB8-AS1 LINC01565 GATA2-AS1 TMED10P2 ABTB1 EEFSEC LOC90246
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around GATA2 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the GATA2 gene promoter:
  • p300
  • Sp1
  • Nkx2-5

Genomic Locations for GATA2 Gene

Genomic Locations for GATA2 Gene
chr3:128,479,422-128,493,187
(GRCh38/hg38)
Size:
13,766 bases
Orientation:
Minus strand
chr3:128,198,265-128,212,030
(GRCh37/hg19)
Size:
13,766 bases
Orientation:
Minus strand

Genomic View for GATA2 Gene

Genes around GATA2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GATA2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GATA2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GATA2 Gene

Proteins for GATA2 Gene

  • Protein details for GATA2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P23769-GATA2_HUMAN
    Recommended name:
    Endothelial transcription factor GATA-2
    Protein Accession:
    P23769
    Secondary Accessions:
    • D3DNB3
    • Q53YE0
    • Q96BH0
    • Q96BH8
    • Q9BUJ6

    Protein attributes for GATA2 Gene

    Size:
    480 amino acids
    Molecular mass:
    50500 Da
    Quaternary structure:
    • Interacts with BRD3 (By similarity). Interacts with AR and CCAR1.
    SequenceCaution:
    • Sequence=AAA35869.1; Type=Miscellaneous discrepancy; Note=Several sequencing errors.; Evidence={ECO:0000305};

    Alternative splice isoforms for GATA2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GATA2 Gene

Post-translational modifications for GATA2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GATA2 Gene

No data available for DME Specific Peptides for GATA2 Gene

Domains & Families for GATA2 Gene

Gene Families for GATA2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Predicted intracellular proteins
  • Transcription factors

Protein Domains for GATA2 Gene

Suggested Antigen Peptide Sequences for GATA2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GATA2: view

No data available for UniProtKB/Swiss-Prot for GATA2 Gene

Function for GATA2 Gene

Molecular function for GATA2 Gene

UniProtKB/Swiss-Prot Function:
Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5-AGATAG-3.
GENATLAS Biochemistry:
endothelial cell transcription factor,GATA sequence binding protein,expressed in immature RBC,mast cell,megakaryocyte,hematopoietic progenitor cell,endothelial cell,embryonic brain,associated with a special class of nuclear bodies. Regulating endothelin 1 (EDN1) expression. Activated by calcineurin (IGF1 induced) to promote myocyte hypertrophy

Phenotypes From GWAS Catalog for GATA2 Gene

Gene Ontology (GO) - Molecular Function for GATA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding IBA --
GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA --
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding IEA --
GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS 19274049
GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA --
genes like me logo Genes that share ontologies with GATA2: view
genes like me logo Genes that share phenotypes with GATA2: view

Human Phenotype Ontology for GATA2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for GATA2 Gene

MGI Knock Outs for GATA2:

Animal Model Products

Targeted motifs for GATA2 Gene
HOMER Transcription Factor Regulatory Elements motif GATA2
  • Consensus sequence: NCCTTATCTC Submotif: canonical Cell Type: K562 GEO ID: GSE18829

Clone Products

  • Addgene plasmids for GATA2

No data available for Enzyme Numbers (IUBMB) and Transcription Factor Targets for GATA2 Gene

Localization for GATA2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GATA2 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GATA2 gene
Compartment Confidence
nucleus 5
cytosol 3
plasma membrane 1
extracellular 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for GATA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA,IEA 27780851
GO:0005654 nucleoplasm TAS --
GO:0005667 transcription factor complex IBA --
GO:0005737 cytoplasm IDA 27780851
genes like me logo Genes that share ontologies with GATA2: view

Pathways & Interactions for GATA2 Gene

genes like me logo Genes that share pathways with GATA2: view

SIGNOR curated interactions for GATA2 Gene

Inactivates:
Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for GATA2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II IEA --
GO:0001655 urogenital system development IEA --
GO:0001709 cell fate determination IEA --
GO:0001764 neuron migration IEA --
GO:0001892 embryonic placenta development IEA --
genes like me logo Genes that share ontologies with GATA2: view

Drugs & Compounds for GATA2 Gene

(14) Drugs for GATA2 Gene - From: ClinicalTrials and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Fludarabine Approved Pharma DNA synthsis inhibitor 1231,1231
Cyclophosphamide Approved, Investigational Pharma Nitrogen mustard alkylating agent and prodrug. 3113
Alkylating Agents Pharma 5057
Antilymphocyte Serum Pharma 464
Antimetabolites Pharma 12587

(8) Additional Compounds for GATA2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with GATA2: view

Transcripts for GATA2 Gene

mRNA/cDNA for GATA2 Gene

Unigene Clusters for GATA2 Gene

GATA binding protein 2:
Representative Sequences:

Clone Products

  • Addgene plasmids for GATA2

Alternative Splicing Database (ASD) splice patterns (SP) for GATA2 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b
SP1: - - - - -
SP2: - - -
SP3: - -
SP4:
SP5: -
SP6:

Relevant External Links for GATA2 Gene

GeneLoc Exon Structure for
GATA2
ECgene alternative splicing isoforms for
GATA2

Expression for GATA2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GATA2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for GATA2 Gene

This gene is overexpressed in Fallopian Tube (x5.1), Prostate (x4.3), Bladder (x4.2), and Uterus (x4.1).

Protein differential expression in normal tissues from HIPED for GATA2 Gene

This gene is overexpressed in Platelet (46.8) and Placenta (22.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for GATA2 Gene



Protein tissue co-expression partners for GATA2 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GATA2 Gene:

GATA2

SOURCE GeneReport for Unigene cluster for GATA2 Gene:

Hs.367725

mRNA Expression by UniProt/SwissProt for GATA2 Gene:

P23769-GATA2_HUMAN
Tissue specificity: Endothelial cells.

Evidence on tissue expression from TISSUES for GATA2 Gene

  • Heart(4.5)
  • Nervous system(4.5)
  • Blood(2.4)
  • Bone marrow(2.3)
  • Kidney(2.2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for GATA2 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • immune
  • integumentary
  • lymphatic
  • nervous
  • respiratory
Regions:
Head and neck:
  • brain
  • cranial nerve
  • ear
  • eye
  • face
  • head
  • middle ear
Thorax:
  • esophagus
  • lung
Abdomen:
  • liver
  • spleen
  • stomach
Limb:
  • lower limb
General:
  • blood
  • blood vessel
  • bone marrow
  • coagulation system
  • lymph node
  • lymph vessel
  • peripheral nervous system
  • red blood cell
  • skin
  • white blood cell
genes like me logo Genes that share expression patterns with GATA2: view

Orthologs for GATA2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for GATA2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GATA2 34 33
  • 99.72 (n)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GATA2 34
  • 97 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GATA2 34
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GATA2 34 33
  • 92.5 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gata2 33
  • 90.56 (n)
mouse
(Mus musculus)
Mammalia Gata2 16 34 33
  • 90.07 (n)
cow
(Bos Taurus)
Mammalia GATA2 34 33
  • 89.35 (n)
OneToOne
chicken
(Gallus gallus)
Aves GATA2 34 33
  • 78.76 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GATA2 34
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100487142 33
  • 77.31 (n)
Str.17047 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.792 33
zebrafish
(Danio rerio)
Actinopterygii gata2a 34 33
  • 72.5 (n)
OneToMany
gata2b 34
  • 60 (a)
OneToMany
gata2 33
fruit fly
(Drosophila melanogaster)
Insecta pnr 35
  • 64 (a)
grn 34 35
  • 27 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea elt-1 34 35
  • 27 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes DAL80 34
  • 17 (a)
ManyToMany
GAT1 34
  • 15 (a)
ManyToMany
GLN3 34
  • 13 (a)
ManyToMany
GZF3 34
  • 13 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 38 (a)
OneToMany
Cin.9192 33
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.9192 33
Species where no ortholog for GATA2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GATA2 Gene

ENSEMBL:
Gene Tree for GATA2 (if available)
TreeFam:
Gene Tree for GATA2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GATA2: view image

Paralogs for GATA2 Gene

Paralogs for GATA2 Gene

(5) SIMAP similar genes for GATA2 Gene using alignment to 2 proteins:

  • GATA2_HUMAN
  • C9J965_HUMAN
genes like me logo Genes that share paralogs with GATA2: view

Variants for GATA2 Gene

Sequence variations from dbSNP and Humsavar for GATA2 Gene

SNP ID Clin Chr 03 pos Variation AA Info Type
rs1033366779 likely-benign, Dendritic cell, monocyte, B lymphocyte, and natural killer lymphocyte deficiency, Lymphedema, primary, with myelodysplasia 128,481,082(-) G/A coding_sequence_variant, synonymous_variant
rs1060500083 uncertain-significance, Dendritic cell, monocyte, B lymphocyte, and natural killer lymphocyte deficiency, Lymphedema, primary, with myelodysplasia 128,486,356(-) C/G coding_sequence_variant, missense_variant
rs1060500084 uncertain-significance, Dendritic cell, monocyte, B lymphocyte, and natural killer lymphocyte deficiency, Lymphedema, primary, with myelodysplasia, not specified 128,486,298(-) CC/AA coding_sequence_variant, missense_variant
rs1060500085 uncertain-significance, Dendritic cell, monocyte, B lymphocyte, and natural killer lymphocyte deficiency, Lymphedema, primary, with myelodysplasia 128,481,898(-) G/T coding_sequence_variant, missense_variant
rs1060500086 uncertain-significance, Dendritic cell, monocyte, B lymphocyte, and natural killer lymphocyte deficiency, Lymphedema, primary, with myelodysplasia 128,481,262(-) C/T coding_sequence_variant, missense_variant

Structural Variations from Database of Genomic Variants (DGV) for GATA2 Gene

Variant ID Type Subtype PubMed ID
nsv516926 CNV loss 19592680
nsv508241 CNV deletion 20534489
nsv508240 CNV deletion 20534489
nsv10318 CNV gain 18304495
esv2759176 CNV loss 17122850
esv2657669 CNV deletion 23128226

Variation tolerance for GATA2 Gene

Residual Variation Intolerance Score: 18.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.76; 86.69% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GATA2 Gene

Human Gene Mutation Database (HGMD)
GATA2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
GATA2

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GATA2 Gene

Disorders for GATA2 Gene

MalaCards: The human disease database

(12) MalaCards diseases for GATA2 Gene - From: HGMD, OMIM, ClinVar, GTR, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

- elite association - COSMIC cancer census association via MalaCards
Search GATA2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

GATA2_HUMAN
  • Immunodeficiency 21 (IMD21) [MIM:614172]: An immunodeficiency disease characterized by profoundly decreased or absent monocytes, B-lymphocytes, natural killer lymphocytes, and circulating and tissue dendritic cells, with little or no effect on T-cell numbers. Clinical features of DCML include susceptibility to disseminated non-tuberculous mycobacterial infections, papillomavirus infections, opportunistic fungal infections, and pulmonary alveolar proteinosis. Bone marrow hypocellularity and dysplasia of myeloid, erythroid, and megakaryocytic lineages are present in most patients, as are karyotypic abnormalities, including monosomy 7 and trisomy 8. This syndrome links susceptibility to mycobacterial, viral, and fungal infections with malignancy and can be transmitted in an autosomal dominant pattern. {ECO:0000269 PubMed:21670465}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Lymphedema, primary, with myelodysplasia (LMPM) [MIM:614038]: A chronic disabling condition characterized by swelling of the extremities due to altered lymphatic flow, associated with myelodysplasia. Patients with lymphedema suffer from recurrent local infections, and physical impairment. {ECO:0000269 PubMed:21892158}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Myelodysplastic syndrome (MDS) [MIM:614286]: A heterogeneous group of closely related clonal hematopoietic disorders. All are characterized by a hypercellular or hypocellular bone marrow with impaired morphology and maturation, dysplasia of the myeloid, megakaryocytic and/or erythroid lineages, and peripheral blood cytopenias resulting from ineffective blood cell production. Included diseases are: refractory anemia (RA), refractory anemia with ringed sideroblasts (RARS), refractory anemia with excess blasts (RAEB), refractory cytopenia with multilineage dysplasia and ringed sideroblasts (RCMD-RS); chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative disease. MDS is considered a premalignant condition in a subgroup of patients that often progresses to acute myeloid leukemia (AML). {ECO:0000269 PubMed:21892162}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Additional Disease Information for GATA2

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with GATA2: view

No data available for Genatlas for GATA2 Gene

Publications for GATA2 Gene

  1. Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells. (PMID: 1714909) Lee ME … Quertermous T (The Journal of biological chemistry 1991) 2 3 4 22 58
  2. Association study of GATA-2 transcription factor gene (GATA2) polymorphism and Parkinson's disease. (PMID: 19864173) Kurzawski M … Droździk M (Parkinsonism & related disorders 2010) 3 22 44 58
  3. Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial cells. (PMID: 1370462) Dorfman DM … Orkin SH (The Journal of biological chemistry 1992) 3 4 22 58
  4. CCAR1 promotes chromatin loading of androgen receptor (AR) transcription complex by stabilizing the association between AR and GATA2. (PMID: 23887938) Seo WY … Kim JH (Nucleic acids research 2013) 3 4 58
  5. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome. (PMID: 21670465) Hsu AP … Holland SM (Blood 2011) 3 4 58

Products for GATA2 Gene

  • Addgene plasmids for GATA2

Sources for GATA2 Gene

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