Aliases for GAREM1 Gene
External Ids for GAREM1 Gene
Previous HGNC Symbols for GAREM1 Gene
This gene encodes an adaptor protein which functions in the epidermal growth factor (EGF) receptor-mediated signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for GAREM1 Gene
GAREM1 (GRB2 Associated Regulator Of MAPK1 Subtype 1) is a Protein Coding gene. Diseases associated with GAREM1 include Renal-Hepatic-Pancreatic Dysplasia. An important paralog of this gene is GAREM2.
UniProtKB/Swiss-Prot Summary for GAREM1 Gene
[Isoform 1]: Acts as an adapter protein that plays a role in intracellular signaling cascades triggered either by the cell surface activated epidermal growth factor receptor and/or cytoplasmic protein tyrosine kinases. Promotes activation of the MAPK/ERK signaling pathway. Plays a role in the regulation of cell proliferation.