Aliases for GAPLINC Gene

Subcategory (RNA class) for GAPLINC Gene

lncRNA

Number of RNA Genes sources:

3 / 14

Aliases for GAPLINC Gene

  • Gastric Adenocarcinoma Associated, Positive CD44 Regulator, Long Intergenic Non-Coding RNA 2 3 5
  • Gastric Adenocarcinoma Predictive Long Intergenic Noncoding RNA 2 3
  • Long Intergenic Non-Protein Coding RNA 1540 2 3
  • GAPLINC 2 168
  • LncRNA-Uc002kmd.1 3
  • TCONS_00026238 3
  • HSALNG0119710 167
  • NONHSAG023235 92
  • RP11-838N2.4 3
  • LINC01540 3

External Ids for GAPLINC Gene

Previous HGNC Symbols for GAPLINC Gene

  • LINC01540

Summaries for GAPLINC Gene

GeneCards Summary for GAPLINC Gene

GAPLINC (Gastric Adenocarcinoma Associated, Positive CD44 Regulator, Long Intergenic Non-Coding RNA) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with GAPLINC include Glioma Susceptibility 1 and Gastric Cancer.

Additional gene information for GAPLINC Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GAPLINC Gene

Genomics for GAPLINC Gene

GeneHancer (GH) Regulatory Elements for GAPLINC Gene

Promoters and enhancers for GAPLINC Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GAPLINC on UCSC Golden Path with GeneCards custom track

Genomic Locations for GAPLINC Gene

Genomic Locations for GAPLINC Gene
chr18:3,466,250-3,486,921
(GRCh38/hg38)
Size:
20,672 bases
Orientation:
Plus strand
chr18:3,466,248-3,478,976
(GRCh37/hg19)
Size:
12,729 bases
Orientation:
Plus strand

Genomic View for GAPLINC Gene

Genes around GAPLINC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GAPLINC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GAPLINC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GAPLINC Gene

Proteins for GAPLINC Gene

Post-translational modifications for GAPLINC Gene

No Post-translational modifications

No data available for DME Specific Peptides for GAPLINC Gene

Domains & Families for GAPLINC Gene

Gene Families for GAPLINC Gene

genes like me logo Genes that share domains with GAPLINC: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for GAPLINC Gene

Function for GAPLINC Gene

Phenotypes From GWAS Catalog for GAPLINC Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GAPLINC Gene

Localization for GAPLINC Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GAPLINC gene
Compartment Confidence
plasma membrane 1
cytoskeleton 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GAPLINC Gene

Pathways & Interactions for GAPLINC Gene

PathCards logo

SuperPathways for GAPLINC Gene

No Data Available
;

Gene Ontology (GO) - Biological Process for GAPLINC Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for GAPLINC Gene

Drugs & Compounds for GAPLINC Gene

No Compound Related Data Available

Transcripts for GAPLINC Gene

mRNA/cDNA for GAPLINC Gene

21 RNACentral transcripts :
2 REFSEQ mRNAs :
3 NCBI additional mRNA sequence :
4 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
7 NONCODE transcripts :
17 LncBook transcripts :
17 LNCipedia transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for GAPLINC Gene

No ASD Table

Relevant External Links for GAPLINC Gene

GeneLoc Exon Structure for
GAPLINC

Expression for GAPLINC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GAPLINC Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GAPLINC

genes like me logo Genes that share expression patterns with GAPLINC: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GAPLINC Gene

Orthologs for GAPLINC Gene

Evolution for GAPLINC Gene

ENSEMBL:
Gene Tree for GAPLINC (if available)
TreeFam:
Gene Tree for GAPLINC (if available)

No data available for Orthologs for GAPLINC Gene

Paralogs for GAPLINC Gene

No data available for Paralogs for GAPLINC Gene

Variants for GAPLINC Gene

Additional dbSNP identifiers (rs#s) for GAPLINC Gene

Additional Variant Information for GAPLINC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GAPLINC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for GAPLINC Gene

Disorders for GAPLINC Gene

MalaCards: The human disease database

(4) MalaCards diseases for GAPLINC Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
glioma susceptibility 1
  • glm1
gastric cancer
  • gastric cancer, somatic
colorectal cancer
  • crc
gastric adenocarcinoma
  • adenocarcinoma of stomach
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for GAPLINC

genes like me logo Genes that share disorders with GAPLINC: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GAPLINC Gene

Publications for GAPLINC Gene

  1. Long Non-Coding RNA ucoo2kmd.1 Regulates CD44-Dependent Cell Growth by Competing for miR-211-3p in Colorectal Cancer. (PMID: 26974151) Wu X … Zhu H (PloS one 2016) 2 3 54
  2. Hypoxia Promotes Gastric Cancer Malignancy Partly through the HIF-1α Dependent Transcriptional Activation of the Long Non-coding RNA GAPLINC. (PMID: 27729869) Liu L … Tian Z (Frontiers in physiology 2016) 2 3 54
  3. Long noncoding RNA GAPLINC regulates CD44-dependent cell invasiveness and associates with poor prognosis of gastric cancer. (PMID: 25277524) Hu Y … Fang JY (Cancer research 2014) 2 3 54
  4. GAPLINC is a predictor of poor prognosis and regulates cell migration and invasion in osteosarcoma. (PMID: 30177521) Liao S … Wang C (Bioscience reports 2018) 3 54
  5. Gastric Adenocarcinoma Predictive Long Intergenic Non-Coding RNA Promotes Tumor Occurrence and Progression in Non-Small Cell Lung Cancer via Regulation of the miR-661/eEF2K Signaling Pathway. (PMID: 30522114) Gu H … Shao H (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018) 3 54

Products for GAPLINC Gene

Sources for GAPLINC Gene