Aliases for GALR3 Gene
External Ids for GALR3 Gene
Previous GeneCards Identifiers for GALR3 Gene
The neuropeptide galanin modulates a variety of physiologic processes including cognition/memory, sensory/pain processing, hormone secretion, and feeding behavior. The human galanin receptors are G protein-coupled receptors that functionally couple to their intracellular effector through distinct signaling pathways. GALR3 is found in many tissues and may be expressed as 1.4-, 2.4-, and 5-kb transcripts [provided by RefSeq, Jul 2008]
GeneCards Summary for GALR3 Gene
GALR3 (Galanin Receptor 3) is a Protein Coding gene. Among its related pathways are Peptide ligand-binding receptors and Signaling by GPCR. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and galanin receptor activity. An important paralog of this gene is GALR1.
UniProtKB/Swiss-Prot Summary for GALR3 Gene
Receptor for the hormone galanin (PubMed:25691535). Receptor for the hormone spexin-1 (PubMed:24517231).
Galanin is widely distributed in the central and peripheral nervous systems and the endocrine system. Three different galanin receptors (GAL1-3) have been identified. Disruption of galanin expression or galanin receptor signaling is seen in many multifactoral conditions.