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GALNTL6 (Polypeptide N-Acetylgalactosaminyltransferase Like 6) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and Metabolism of proteins. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and polypeptide N-acetylgalactosaminyltransferase activity. An important paralog of this gene is GALNT10.
GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
---|---|---|---|---|---|---|---|---|---|---|
GH04J171812 | Promoter | 1.3 | EPDnew Ensembl CraniofacialAtlas | 258.2 | +1.5 | 1547 | 3.2 | L3MBTL2 EZH2 RAD21 ZNF579 CBFA2T3 | GALNTL6 HSALNG0038559 LOC441052 piR-50443-300 | |
GH04J171853 | Enhancer | 0.2 | Ensembl | 5.9 | +39.8 | 39847 | 0.6 | GALNTL6 piR-50443-300 piR-37309-005 | ||
GH04J171852 | Enhancer | 0.2 | FANTOM5 | 3.2 | +40.8 | 40761 | 0.3 | GALNTL6 piR-50443-300 piR-37309-005 | ||
GH04J171817 | Enhancer | 0.3 | Ensembl | 0.4 | +5.1 | 5147 | 0.8 | SPI1 | LOC441052 GALNTL6 piR-50443-300 | |
GH04J171879 | Enhancer | 0.4 | Ensembl ENCODE | 0.2 | +68.0 | 68003 | 1.4 | JUND | piR-50443-300 GALNTL6 piR-37309-005 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity | IEA,IDA | 22186971 |
GO:0016740 | transferase activity | IEA | -- |
GO:0016757 | transferase activity, transferring glycosyl groups | IEA | -- |
GO:0030246 | carbohydrate binding | IEA | -- |
GO:0046872 | metal ion binding | IEA | -- |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0000139 | Golgi membrane | IEA | -- |
GO:0005794 | Golgi apparatus | IEA,IBA | 21873635 |
GO:0016020 | membrane | IEA | -- |
GO:0016021 | integral component of membrane | IEA | -- |
SuperPathway | Contained pathways | ||
---|---|---|---|
1 | Mucin type O-glycan biosynthesis | ||
2 | Metabolism of proteins | ||
3 | O-linked glycosylation | ||
4 | Metabolism |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006486 | protein glycosylation | IEA | -- |
GO:0018215 | protein phosphopantetheinylation | IEA | -- |
GO:0018243 | protein O-linked glycosylation via threonine | IDA | 22186971 |
Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
---|---|---|---|---|---|---|
Lactosamine |
|
13000-25-4 |
|
|||
UDP-N-acetyl-alpha-D-galactosamine |
|
|
||||
Uridine diphosphate-N-acetylgalactosamine |
|
7277-98-7 |
|
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | GALNTL6 30 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | GALNTL6 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | GALNTL6 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | GALNTL6 30 31 |
|
OneToOne | |
Mouse (Mus musculus) |
Mammalia | Galntl6 30 17 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Galntl6 30 |
|
||
Cow (Bos Taurus) |
Mammalia | GALNTL6 30 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | GALNTL6 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | GALNTL6 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | galntl6 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | GALNTL6 31 |
|
OneToOne | |
si:ch211-15e22.3 30 |
|
||||
Fruit Fly (Drosophila melanogaster) |
Insecta | pgant6 31 |
|
ManyToMany | |
pgant4 31 |
|
ManyToMany | |||
pgant8 31 |
|
ManyToMany | |||
CG31776 31 |
|
ManyToMany | |||
Worm (Caenorhabditis elegans) |
Secernentea | gly-10 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
No disorders were found for GALNTL6 Gene.