Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GALNT18 Gene

Aliases for GALNT18 Gene

  • Polypeptide N-Acetylgalactosaminyltransferase 18 2 3 4 5
  • Polypeptide GalNAc Transferase 18 2 3 4
  • UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase-Like 4 2 3
  • UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 18 2 3
  • UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 4 3 4
  • Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 4 3 4
  • Protein-UDP Acetylgalactosaminyltransferase-Like Protein 4 3 4
  • Polypeptide GalNAc Transferase-Like Protein 4 3 4
  • Pp-GaNTase-Like Protein 4 3 4
  • GalNAc-T-Like Protein 4 3 4
  • GalNAc-T18 3 4
  • GALNTL4 3 4
  • UDP-N-Acetyl-Alpha-D-Galactosamine:Polypeptide N-Acetylgalactosaminyltransferase 15 3
  • Putative Polypeptide N-Acetylgalactosaminyltransferase-Like Protein 4 3
  • GalNAc-Transferase 18 3
  • EC 2.4.1.41 4
  • GalNAc-T15 3
  • GALNACT18 3
  • GALNT15 3

External Ids for GALNT18 Gene

Previous HGNC Symbols for GALNT18 Gene

  • GALNTL4

Summaries for GALNT18 Gene

GeneCards Summary for GALNT18 Gene

GALNT18 (Polypeptide N-Acetylgalactosaminyltransferase 18) is a Protein Coding gene. Among its related pathways are O-linked glycosylation and Mucin type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and polypeptide N-acetylgalactosaminyltransferase activity. An important paralog of this gene is GALNT9.

UniProtKB/Swiss-Prot for GALNT18 Gene

  • Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.

Additional gene information for GALNT18 Gene

No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GALNT18 Gene

Genomics for GALNT18 Gene

GeneHancer (GH) Regulatory Elements for GALNT18 Gene

Promoters and enhancers for GALNT18 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J011619 Promoter/Enhancer 2.2 EPDnew FANTOM5 Ensembl ENCODE 654.7 +1.3 1326 5 SP1 NKRF FOS MYC POLR2A RELA IKZF1 GLIS2 PKNOX1 ZBTB8A GALNT18 CTR9 ENSG00000255462
GH11J011577 Enhancer 0.8 Ensembl dbSUPER 19 +42.1 42144 6.6 SP1 RXRA YY1 POLR2A NR2F2 RAD21 HNF4A MAX HNF4G NR2F6 GALNT18 ENSG00000255462
GH11J011659 Enhancer 0.5 Ensembl 21.6 -39.0 -39017 3.1 CTCF IKZF2 RELA SCRT2 ZNF10 ELF1 POLR2A GALNT18 MIR4299 ENSG00000280288
GH11J011583 Enhancer 0.9 Ensembl ENCODE dbSUPER 12 +37.3 37340 1.8 PRDM1 IKZF1 ZNF692 SP1 FOS FOSL2 JUND GALNT18 ENSG00000255462
GH11J011567 Enhancer 1.1 Ensembl ENCODE dbSUPER 10.1 +53.0 53033 4.4 ZNF600 PRDM10 ZNF692 PKNOX1 SCRT2 SCRT1 NR2F2 USF2 ZNF189 ZFP69B ENSG00000255462 GALNT18 GC11P011552
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GALNT18 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GALNT18 Gene

Genomic Locations for GALNT18 Gene
chr11:11,270,874-11,622,045
(GRCh38/hg38)
Size:
351,172 bases
Orientation:
Minus strand
chr11:11,292,421-11,643,561
(GRCh37/hg19)
Size:
351,141 bases
Orientation:
Minus strand

Genomic View for GALNT18 Gene

Genes around GALNT18 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GALNT18 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GALNT18 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GALNT18 Gene

Proteins for GALNT18 Gene

  • Protein details for GALNT18 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P9A2-GLT18_HUMAN
    Recommended name:
    Polypeptide N-acetylgalactosaminyltransferase 18
    Protein Accession:
    Q6P9A2
    Secondary Accessions:
    • O95903
    • Q8NDY9

    Protein attributes for GALNT18 Gene

    Size:
    607 amino acids
    Molecular mass:
    69561 Da
    Cofactor:
    Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAD20062.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for GALNT18 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GALNT18 Gene

Post-translational modifications for GALNT18 Gene

  • Glycosylation at isoforms=195, isoforms=146, and isoforms=320
  • Modification sites at PhosphoSitePlus

Other Protein References for GALNT18 Gene

No data available for DME Specific Peptides for GALNT18 Gene

Domains & Families for GALNT18 Gene

Gene Families for GALNT18 Gene

Suggested Antigen Peptide Sequences for GALNT18 Gene

GenScript: Design optimal peptide antigens:
  • UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase-like protein 4 (GLTL4_HUMAN)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4 (Q58A54_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q6P9A2

UniProtKB/Swiss-Prot:

GLT18_HUMAN :
  • There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
  • Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Domain:
  • There are two conserved domains in the glycosyltransferase region: the N-terminal domain (domain A, also called GT1 motif), which is probably involved in manganese coordination and substrate binding and the C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is probably involved in catalytic reaction and UDP-Gal binding.
  • The ricin B-type lectin domain binds to GalNAc and contributes to the glycopeptide specificity.
Family:
  • Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
genes like me logo Genes that share domains with GALNT18: view

Function for GALNT18 Gene

Molecular function for GALNT18 Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=L-seryl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-seryl-[protein] + H(+) + UDP; Xref=Rhea:RHEA:23956, Rhea:RHEA-COMP:9863, Rhea:RHEA-COMP:12788, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:53604, ChEBI:CHEBI:58223, ChEBI:CHEBI:67138; EC=2.4.1.41;.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=L-threonyl-[protein] + UDP-N-acetyl-alpha-D-galactosamine = 3-O-[N-acetyl-alpha-D-galactosaminyl]-L-threonyl-[protein] + H(+) + UDP; Xref=Rhea:RHEA:52424, Rhea:RHEA-COMP:11060, Rhea:RHEA-COMP:11689, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013, ChEBI:CHEBI:58223, ChEBI:CHEBI:67138, ChEBI:CHEBI:87075; EC=2.4.1.41;.

Enzyme Numbers (IUBMB) for GALNT18 Gene

Phenotypes From GWAS Catalog for GALNT18 Gene

Gene Ontology (GO) - Molecular Function for GALNT18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity IEA,IDA 22186971
GO:0016740 transferase activity IEA --
GO:0016757 transferase activity, transferring glycosyl groups IEA --
GO:0030246 carbohydrate binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with GALNT18: view
genes like me logo Genes that share phenotypes with GALNT18: view

Animal Models for GALNT18 Gene

MGI Knock Outs for GALNT18:

Animal Model Products

CRISPR Products

miRNA for GALNT18 Gene

miRTarBase miRNAs that target GALNT18

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GALNT18

Clone Products

  • Applied Biological Materials (abm): Clones for GALNT18 - Now 50% OFF >
  • * GALNT18 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * GALNT18 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GALNT18 Gene

Localization for GALNT18 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GALNT18 Gene

Golgi apparatus membrane; Single-pass type II membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GALNT18 gene
Compartment Confidence
golgi apparatus 4
plasma membrane 2
mitochondrion 2
peroxisome 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for GALNT18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000139 Golgi membrane IEA --
GO:0005575 cellular_component ND --
GO:0005794 Golgi apparatus IBA 21873635
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with GALNT18: view

Pathways & Interactions for GALNT18 Gene

genes like me logo Genes that share pathways with GALNT18: view

Pathways by source for GALNT18 Gene

UniProtKB/Swiss-Prot Q6P9A2-GLT18_HUMAN

  • Pathway: Protein modification; protein glycosylation.

Gene Ontology (GO) - Biological Process for GALNT18 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006486 protein glycosylation IEA --
GO:0006493 protein O-linked glycosylation IDA 22186971
genes like me logo Genes that share ontologies with GALNT18: view

No data available for SIGNOR curated interactions for GALNT18 Gene

Drugs & Compounds for GALNT18 Gene

(5) Drugs for GALNT18 Gene - From: PharmGKB and HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Cisplatin Approved Pharma Inhibits DNA synthesis,chemotherapy drug, Potent pro-apoptotic anticancer agent; activates caspase-3, Platinum 3185
tocilizumab Approved Pharma Immunotherapies 0
Calcium Approved Nutra 7611
Manganese Approved Nutra 41
Uridine 5'-diphosphate Experimental Pharma 0

(3) Additional Compounds for GALNT18 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Lactosamine
  • 2-amino-2-Deoxy-4-O-beta-D-galactopyranosyl-D-glucose
  • 2-amino-2-Deoxy-4-O-beta-delta-galactopyranosyl-delta-glucose
  • beta-D-Galactopyranosyl-(1->4)-2-amino-2-deoxy-D-glucose
  • beta-D-Galactopyranosyl-(1->4)-D-glucosamine
  • beta-delta-Galactopyranosyl-(1->4)-2-amino-2-deoxy-delta-glucose
13000-25-4
UDP-N-acetyl-alpha-D-galactosamine
  • (2R,3R,4R,5R,6R)-3-(acetylamino)-4,5-Dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name)
  • URIDINE-diphosphATE-N-acetylgalactosamine
  • (2R,3R,4R,5R,6R)-3-(acetylamino)-4,5-Dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphoric acid (non-preferred name)
  • UDP-N-Acetyl-a-D-galactosamine
  • UDP-N-Acetyl-α-D-galactosamine
Uridine diphosphate-N-acetylgalactosamine
  • UDP-N-Acetyl-D-galactosamine
  • UDP-N-Acetyl-delta-galactosamine
  • UDP-N-Acetylgalactosamine
  • Uridine 5'-diphospho-N-acetylgalactosamine
  • Uridine diphosphate-N-acetyl-D-galactosamine
7277-98-7
genes like me logo Genes that share compounds with GALNT18: view

Transcripts for GALNT18 Gene

mRNA/cDNA for GALNT18 Gene

(2) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(45) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for GALNT18 Gene

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GALNT18

Clone Products

  • Applied Biological Materials (abm): Clones for GALNT18 - Now 50% OFF >
  • * GALNT18 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * GALNT18 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for GALNT18 Gene

No ASD Table

Relevant External Links for GALNT18 Gene

GeneLoc Exon Structure for
GALNT18
ECgene alternative splicing isoforms for
GALNT18

Expression for GALNT18 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GALNT18 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for GALNT18 Gene

This gene is overexpressed in Testis (43.8) and Urine (20.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GALNT18 Gene



Protein tissue co-expression partners for GALNT18 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GALNT18 Gene:

GALNT18

SOURCE GeneReport for Unigene cluster for GALNT18 Gene:

Hs.655152

Evidence on tissue expression from TISSUES for GALNT18 Gene

  • Nervous system(4.5)
genes like me logo Genes that share expression patterns with GALNT18: view

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GALNT18 Gene

Orthologs for GALNT18 Gene

This gene was present in the common ancestor of animals.

Orthologs for GALNT18 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GALNT18 35
  • 100 (a)
OneToOne
GALNTL4 34
  • 99.76 (n)
cow
(Bos Taurus)
Mammalia GALNTL4 35 34
  • 93.08 (n)
OneToOne
dog
(Canis familiaris)
Mammalia GALNT18 35 34
  • 92.81 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GALNT18 35
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Galnt18 17 35 34
  • 91.82 (n)
rat
(Rattus norvegicus)
Mammalia Galnt18 34
  • 91.21 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 91 (a)
OneToMany
-- 35
  • 67 (a)
OneToMany
chicken
(Gallus gallus)
Aves GALNTL4 35 34
  • 78.75 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 90 (a)
OneToMany
-- 35
  • 85 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii galnt18b 35 34
  • 75.86 (n)
OneToMany
galnt18a 35
  • 64 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG7579 35
  • 28 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea gly-8 35
  • 29 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 28 (a)
ManyToMany
Species where no ortholog for GALNT18 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for GALNT18 Gene

ENSEMBL:
Gene Tree for GALNT18 (if available)
TreeFam:
Gene Tree for GALNT18 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for GALNT18: view image

Paralogs for GALNT18 Gene

Variants for GALNT18 Gene

Sequence variations from dbSNP and Humsavar for GALNT18 Gene

SNP ID Clin Chr 11 pos Variation AA Info Type
rs1000006104 -- 11,457,176(-) C/G/T genic_upstream_transcript_variant, intron_variant
rs1000006998 -- 11,454,939(-) A/G genic_upstream_transcript_variant, intron_variant
rs1000019140 -- 11,378,304(-) C/A intron_variant
rs1000045723 -- 11,575,127(-) A/C genic_upstream_transcript_variant, intron_variant
rs1000049232 -- 11,382,498(-) T/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for GALNT18 Gene

Variant ID Type Subtype PubMed ID
dgv1645n54 CNV loss 21841781
dgv1646n54 CNV loss 21841781
dgv1647n54 CNV loss 21841781
dgv1648n54 CNV loss 21841781
dgv1649n54 CNV loss 21841781
dgv1650n54 CNV loss 21841781
dgv1651n54 CNV loss 21841781
dgv21e180 CNV loss 20482838
dgv586n106 CNV deletion 24896259
dgv587n106 CNV deletion 24896259
esv1000870 CNV deletion 20482838
esv1001378 CNV insertion 20482838
esv1225155 CNV deletion 17803354
esv22181 CNV loss 19812545
esv24877 CNV loss 19812545
esv2619721 CNV insertion 19546169
esv2671588 CNV deletion 23128226
esv2676595 CNV deletion 23128226
esv2744107 CNV deletion 23290073
esv2744109 CNV deletion 23290073
esv2744110 CNV deletion 23290073
esv2744111 CNV deletion 23290073
esv2744112 CNV deletion 23290073
esv2759804 CNV loss 17122850
esv29788 CNV gain 19812545
esv3258607 CNV deletion 24192839
esv32920 CNV gain+loss 17666407
esv34098 CNV loss 18971310
esv3427984 CNV duplication 20981092
esv3547320 CNV deletion 23714750
esv3579368 CNV loss 25503493
esv3625372 CNV loss 21293372
esv3625373 CNV loss 21293372
esv3625374 CNV loss 21293372
esv3625375 CNV loss 21293372
esv5536 CNV gain 19470904
esv6523 CNV loss 19470904
esv990208 CNV deletion 20482838
nsv1070938 CNV deletion 25765185
nsv1078363 CNV deletion 25765185
nsv442221 CNV loss 18776908
nsv474009 CNV novel sequence insertion 20440878
nsv474509 CNV novel sequence insertion 20440878
nsv475909 CNV novel sequence insertion 20440878
nsv476839 CNV novel sequence insertion 20440878
nsv478121 CNV novel sequence insertion 20440878
nsv483000 CNV loss 15286789
nsv508618 CNV deletion 20534489
nsv509389 CNV insertion 20534489
nsv518823 CNV loss 19592680
nsv519371 CNV loss 19592680
nsv522669 CNV loss 19592680
nsv523052 CNV loss 19592680
nsv524019 CNV loss 19592680
nsv528861 CNV loss 19592680
nsv553480 CNV loss 21841781
nsv553493 CNV loss 21841781
nsv553509 CNV gain+loss 21841781
nsv7678 CNV deletion 18451855
nsv832064 CNV gain 17160897
nsv832065 CNV gain 17160897
nsv957886 CNV deletion 24416366
nsv975884 CNV duplication 23825009

Variation tolerance for GALNT18 Gene

Residual Variation Intolerance Score: 8.04% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.73; 32.84% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for GALNT18 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GALNT18
Human Gene Mutation Database (HGMD)
GALNT18

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GALNT18 Gene

Disorders for GALNT18 Gene

Additional Disease Information for GALNT18

No disorders were found for GALNT18 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GALNT18 Gene

Publications for GALNT18 Gene

  1. UDP-N-acetyl-α-D-galactosamine:polypeptide N-acetylgalactosaminyltransferases: completion of the family tree. (PMID: 22186971) Raman J … Tabak LA (Glycobiology 2012) 2 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 58
  4. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. (PMID: 28611215) Fei T … Brown M (Proceedings of the National Academy of Sciences of the United States of America 2017) 3 58
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin EL … Gygi SP (Cell 2015) 3 58

Products for GALNT18 Gene

Sources for GALNT18 Gene

Content
Loading form....