Aliases for GAL3ST4 Gene
External Ids for GAL3ST4 Gene
Previous GeneCards Identifiers for GAL3ST4 Gene
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates. [provided by RefSeq, Jul 2008]
GeneCards Summary for GAL3ST4 Gene
GAL3ST4 (Galactose-3-O-Sulfotransferase 4) is a Protein Coding gene. Diseases associated with GAL3ST4 include Fanconi Anemia, Complementation Group G and Scoliosis. Among its related pathways are Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include galactosylceramide sulfotransferase activity and proteoglycan sulfotransferase activity. An important paralog of this gene is GAL3ST2.
UniProtKB/Swiss-Prot Summary for GAL3ST4 Gene
Catalyzes the transfer of sulfate to beta-1,3-linked galactose residues in O-linked glycoproteins. Good substrates include asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc.