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This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 and type 2 (Galbeta 1-3/1-4GlcNAc-R) oligosaccharides with similar efficiencies, and on core 1 glycans. This enzyme has been i... See more...
Aliases for GAL3ST2 Gene
Aliases for GAL3ST2 Gene
External Ids for GAL3ST2 Gene
- HGNC: 24869
- NCBI Entrez Gene: 64090
- Ensembl: ENSG00000154252
- OMIM®: 608237
- UniProtKB/Swiss-Prot: Q9H3Q3
Previous GeneCards Identifiers for GAL3ST2 Gene
- GC11M068343
- GC11M067490
- GC11M066059
- GC11M065585
- GC02P243038
- GC02P242436
- GC02P242364
- GC02P242716
- GC02P234469
Summaries for GAL3ST2 Gene
-
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the hydroxyl at C-3 of nonreducing beta-galactosyl residues, and it can act on both type 1 and type 2 (Galbeta 1-3/1-4GlcNAc-R) oligosaccharides with similar efficiencies, and on core 1 glycans. This enzyme has been implicated in tumor metastasis processes. This gene is different from the GAL3ST3 gene located on chromosome 11, which has also been referred to as GAL3ST2 and encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 2. [provided by RefSeq, Jul 2008]
GeneCards Summary for GAL3ST2 Gene
GAL3ST2 (Galactose-3-O-Sulfotransferase 2) is a Protein Coding gene. Among its related pathways are Cytochrome P450 - arranged by substrate type. Gene Ontology (GO) annotations related to this gene include sulfotransferase activity and galactosylceramide sulfotransferase activity. An important paralog of this gene is GAL3ST4.
UniProtKB/Swiss-Prot Summary for GAL3ST2 Gene
-
Transfers a sulfate group to the hydroxyl group at C3 of non-reducing beta-galactosyl residues. Acts both on type 1 (Gal-beta-1,3-GlcNAc) and type 2 (Gal-beta-1,4-GlcNAc) chains with similar efficiency.
Additional gene information for GAL3ST2 Gene
- HGNC (24869)
- NCBI Entrez Gene (64090)
- Ensembl (ENSG00000154252)
- OMIM® (608237)
- UniProtKB/Swiss-Prot (Q9H3Q3)
- Open Targets Platform(ENSG00000154252)
- Monarch Initiative
- Search for GAL3ST2 at DataMed
- Search for GAL3ST2 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GAL3ST2 Gene
Genomics for GAL3ST2 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GAL3ST2 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GAL3ST2 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GAL3ST2
- Top Transcription factor binding sites by QIAGEN in the GAL3ST2 gene promoter:
-
- C/EBPalpha
- E4BP4
- Hlf
Genomic Locations for GAL3ST2 Gene
Latest Assembly
- chr2:241,776,822-241,804,287
- (GRCh38/hg38)
- Size:
- 27,466 bases
- Orientation:
- Plus strand
Previous Assembly
- chr2:242,716,237-242,743,702
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 27,466 bases
- Orientation:
- Plus strand
- chr2:242,716,240-242,743,623
- (GRCh37/hg19 by Ensembl)
- Size:
- 27,384 bases
- Orientation:
- Plus strand
Genomic View for GAL3ST2 Gene
Genes around GAL3ST2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q37.3 by HGNC
- 2q37.3 by Entrez Gene
- 2q37.3 by Ensembl
GAL3ST2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GAL3ST2 Gene
Proteins for GAL3ST2 Gene
-
Protein details for GAL3ST2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9H3Q3-G3ST2_HUMAN
- Recommended name:
- Galactose-3-O-sulfotransferase 2
- Protein Accession:
- Q9H3Q3
- Q17RK0
- Q57Z52
Protein attributes for GAL3ST2 Gene
- Size:
- 398 amino acids
- Molecular mass:
- 46110 Da
- Quaternary structure:
- No Data Available
Protein Expression for GAL3ST2 Gene
Post-translational modifications for GAL3ST2 Gene
Other Protein References for GAL3ST2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- Novus Biologicals Antibodies for GAL3ST2
- Invitrogen Antibodies for GAL3ST2 (AFLGC-Gal3st2)
- antibodies-online: Show 4 available GAL3ST2 Antibodies ranked by validation data
-
Biorbyt antibodies for GAL3ST2
Protein products for research
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for GAL3ST2
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- Novus Biologicals proteins for GAL3ST2
- antibodies-online: Show 4 available GAL3ST2 Proteins ranked by validation data
- Compare Top GAL3ST2 Proteins
-
Quality Products:
Assay products for research
No data available for DME Specific Peptides for GAL3ST2 Gene
Domains & Families for GAL3ST2 Gene
Gene Families for GAL3ST2 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for GAL3ST2 Gene
- InterPro:
- Blocks:
-
- Galactose-3-O-sulfotransferase
- ProtoNet:
Suggested Antigen Peptide Sequences for GAL3ST2 Gene
- GenScript: Design optimal peptide antigens:
-
- Glycoprotein beta-Gal 3'-sulfotransferase 2 (G3ST2_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9H3Q3- Family:
-
- Belongs to the galactose-3-O-sulfotransferase family.
Function for GAL3ST2 Gene
Molecular function for GAL3ST2 Gene
- UniProtKB/Swiss-Prot Function:
- Transfers a sulfate group to the hydroxyl group at C3 of non-reducing beta-galactosyl residues. Acts both on type 1 (Gal-beta-1,3-GlcNAc) and type 2 (Gal-beta-1,4-GlcNAc) chains with similar efficiency.
- UniProtKB/Swiss-Prot BiophysicochemicalProperties:
- pH dependence: Optimum pH is 6.0-6.5.;
- UniProtKB/Swiss-Prot EnzymeRegulation:
- Strongly inhibited by Cu(2+) and Zn(2+).
Enzyme Numbers (IUBMB) for GAL3ST2 Gene
Phenotypes From GWAS Catalog for GAL3ST2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001733 | galactosylceramide sulfotransferase activity | IEA | -- |
| GO:0005515 | protein binding | IPI | 25416956 |
| GO:0008146 | sulfotransferase activity | IDA | 11029462 |
| GO:0016740 | transferase activity | IEA | -- |
| GO:0050694 | galactose 3-O-sulfotransferase activity | IBA | 21873635 |
Phenotypes for GAL3ST2 Gene
- GenomeRNAi human phenotypes for GAL3ST2:
-
- Increased vaccinia virus (VACV) infection
- Decreased viability
- no effect
- Decreased viability ratio
- Dynamic nuclei (hole, folded or small irregular)
- shRNA abundance <= 25%
- Decreased viability (cell death)
- No cells
- Decreased shRNA abundance
- Increased IL-8 secretion
- Decreased infection with West Nile virus (WNV)
- Decreased West Nile virus (WNV) infection
- Downregulation of RLR pathway after Sendai virus (SeV) infection
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GAL3ST2 - Starting at $85 >
- * GAL3ST2 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
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-
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miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GAL3ST2
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Clone products for research
- Applied Biological Materials (abm): Clones for GAL3ST2 - Starting at $45 >
- * GAL3ST2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GAL3ST2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GAL3ST2
Cell Lines for research
-
Horizon Cell Lines for GAL3ST2
No data available for Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GAL3ST2 Gene
Localization for GAL3ST2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GAL3ST2 Gene
- Golgi apparatus, Golgi stack membrane. Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| golgi apparatus | 4 |
| extracellular | 2 |
| endoplasmic reticulum | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IEA | -- |
| GO:0016020 | membrane | TAS | 11029462 |
| GO:0016021 | integral component of membrane | IEA | -- |
| GO:0032580 | Golgi cisterna membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for GAL3ST2 Gene
Pathways & Interactions for GAL3ST2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytochrome P450 - arranged by substrate type | ||
Pathways by source for GAL3ST2 Gene
1 BioSystems pathway for GAL3ST2 Gene
UniProtKB/Swiss-Prot Q9H3Q3-G3ST2_HUMAN
- Pathway: Protein modification; carbohydrate sulfation.
Interacting Proteins for GAL3ST2 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0008150 | biological_process | ND | -- |
| GO:0009101 | glycoprotein biosynthetic process | IBA | 21873635 |
| GO:0009247 | glycolipid biosynthetic process | IEA | -- |
No data available for SIGNOR curated interactions for GAL3ST2 Gene
Transcripts for GAL3ST2 Gene
mRNA/cDNA for GAL3ST2 Gene
- 1 REFSEQ mRNAs :
- 3 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000192314 1452 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for GAL3ST2 - Starting at $85 >
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- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for GAL3ST2
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-
Santa Cruz Biotechnology (SCBT) CRISPR for GAL3ST2
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for GAL3ST2
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Clone products for research
- Applied Biological Materials (abm): Clones for GAL3ST2 - Starting at $45 >
- * GAL3ST2 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for GAL3ST2
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GAL3ST2
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8a | · | 8b | ^ | 9 | ^ | 10a | · | 10b | · | 10c | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | 12b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||
| SP9: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP10: | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||
| SP11: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||
| SP12: | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP13: |
Relevant External Links for GAL3ST2 Gene
- GeneLoc Exon Structure for
- GAL3ST2
Expression for GAL3ST2 Gene
mRNA differential expression in normal tissues according to GTEx for GAL3ST2 Gene
This gene is overexpressed in Colon - Transverse (x21.4).
This gene is overexpressed in Oral epithelium (63.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for GAL3ST2 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GAL3ST2
SOURCE GeneReport for Unigene cluster for GAL3ST2 Gene:
Hs.632556mRNA Expression by UniProt/SwissProt for GAL3ST2 Gene:
Q9H3Q3-G3ST2_HUMAN
Tissue specificity:
Ubiquitous. Detected in heart, stomach, colon, liver and spleen, in epithelial cells lining the lower to middle layer of the crypts in colonic mucosa, hepatocytes surrounding the central vein of the liver, extravillous cytotrophoblasts in the basal plate of the septum of the placenta, renal tubules of the kidney, and neuronal cells of the cerebral cortex.
Evidence on tissue expression from TISSUES for GAL3ST2 Gene
- Intestine(4.3)
Primer products for research
-
OriGene qPCR primer pairs for GAL3ST2
Gene Expression Assays for research
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for GAL3ST2 Gene
Orthologs for GAL3ST2 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GAL3ST2 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | GAL3ST2 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GAL3ST2 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Gm9994 30 31 |
|
OneToMany | |
| Gal3st2 17 31 |
|
OneToMany | |||
| Gm6086 31 |
|
OneToMany | |||
| Gal3st2b 17 |
|
||||
| Gal3st2c 17 |
|
||||
| Rat (Rattus norvegicus) |
Mammalia | Gal3st2 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | GAL3ST2 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | -- 31 |
|
OneToMany | |
| -- 31 |
|
OneToMany | |||
| Chicken (Gallus gallus) |
Aves | GAL3ST2 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | GAL3ST2 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | LOC556126 30 |
|
||
| CABZ01079005.1 31 |
|
ManyToMany | |||
| si:dkey-246m18.2 31 |
|
ManyToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
ManyToMany | |
| -- 31 |
|
ManyToMany | |||
| -- 31 |
|
ManyToMany |
- Species where no ortholog for GAL3ST2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for GAL3ST2 Gene
- ENSEMBL:
- Gene Tree for GAL3ST2 (if available)
- TreeFam:
- Gene Tree for GAL3ST2 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GAL3ST2: view image
Paralogs for GAL3ST2 Gene
Variants for GAL3ST2 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GAL3ST2 Gene
| SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs372108744 | Likely Pathogenic: not provided | 241,801,858(+) |
C/T NM_022134.3(GAL3ST2):c.197C>T (p.Thr66Met) |
MISSENSE | |
| rs78620448 | Conflicting Interpretations: not specified; not provided | 241,776,985(+) |
G/A NM_022134.3(GAL3ST2):c.29+1G>A |
SPLICE_DONOR | |
| rs12469459 | - |
p.Met4Leu |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv165e55 | CNV | loss | 17911159 |
| dgv4200n100 | CNV | loss | 25217958 |
| dgv4201n100 | CNV | gain | 25217958 |
| esv3594840 | CNV | loss | 21293372 |
| esv3594841 | CNV | loss | 21293372 |
| esv3594842 | CNV | gain | 21293372 |
| esv3893578 | CNV | loss | 25118596 |
| nsv1002941 | CNV | gain | 25217958 |
| nsv1006733 | CNV | gain | 25217958 |
| nsv10232 | CNV | gain+loss | 18304495 |
| nsv584982 | CNV | loss | 21841781 |
| nsv955300 | CNV | deletion | 24416366 |
| nsv955301 | CNV | deletion | 24416366 |
| nsv997984 | CNV | gain | 25217958 |
Residual Variation Intolerance Score:
90.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
5.73;
73.29% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GAL3ST2 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GAL3ST2 Gene
Disorders for GAL3ST2 Gene
Additional Disease Information for GAL3ST2
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No disorders were found for GAL3ST2 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAL3ST2 Gene
Publications for GAL3ST2 Gene
- Molecular cloning and characterization of a human beta-Gal-3'-sulfotransferase that acts on both type 1 and type 2 (Gal beta 1-3/1-4GlcNAc-R) oligosaccharides. (PMID: 11029462) Honke K … Taniguchi N (The Journal of biological chemistry 2001) 2 3 4 23
- Gal3ST-2 involved in tumor metastasis process by regulation of adhesion ability to selectins and expression of integrins. (PMID: 15921657) Shi BZ … Wu XZ (Biochemical and biophysical research communications 2005) 3 23
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- AMPK Interactome Reveals New Function in Non-homologous End Joining DNA Repair. (PMID: 31900314) Chen Z … Chen J (Molecular & cellular proteomics : MCP 2020) 3
- E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins. (PMID: 29676528) Khanna R … Parnaik VK (The FEBS journal 2018) 3
ExternalLinks
Products for GAL3ST2 Gene
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- High-throughput Antibody Production Service
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- Novus Biologicals proteins for GAL3ST2
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- Invitrogen Antibodies for GAL3ST2 (AFLGC-Gal3st2)
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- antibodies-online: Show 4 available GAL3ST2 Antibodies ranked by validation data
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- Quality Products:
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- Biorbyt antibodies for GAL3ST2
Sources for GAL3ST2 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB