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Aliases for GAGE2E Gene

Aliases for GAGE2E Gene

  • G Antigen 2E 2 3 4 5
  • GAGE-2E 3 4
  • GAGE8 3

External Ids for GAGE2E Gene

Previous GeneCards Identifiers for GAGE2E Gene

  • GC0XU900863
  • GC0XP049087
  • GC0XP049091
  • GC0XP049199
  • GC0XP049207
  • GC0XP049210
  • GC0XP049224
  • GC0XP049227
  • GC0XP049238
  • GC0XP049248
  • GC0XP049254
  • GC0XP049259
  • GC0XP049264
  • GC0XP049562

Summaries for GAGE2E Gene

GeneCards Summary for GAGE2E Gene

GAGE2E (G Antigen 2E) is a Protein Coding gene. An important paralog of this gene is GAGE12F.

Additional gene information for GAGE2E Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GAGE2E Gene

Genomics for GAGE2E Gene

GeneHancer (GH) Regulatory Elements for GAGE2E Gene

Promoters and enhancers for GAGE2E Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ049341 Promoter 0.6 Ensembl 600.7 +0.4 409 0.4 RB1 GAGE12B GAGE2E GAGE12C
GH0XJ049532 Promoter 0.5 EPDnew 0.1 +191.0 190971 0.1 GAGE12C GAGE2E
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GAGE2E on UCSC Golden Path with GeneCards custom track

Genomic Locations for GAGE2E Gene

Genomic Locations for GAGE2E Gene
4,731 bases
Plus strand
7,317 bases
Plus strand

Genomic View for GAGE2E Gene

Genes around GAGE2E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GAGE2E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GAGE2E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for RefSeq DNA sequence for GAGE2E Gene

Proteins for GAGE2E Gene

  • Protein details for GAGE2E Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    G antigen 2E
    Protein Accession:
    Secondary Accessions:
    • A0A087WUD6
    • A6NFB1

    Protein attributes for GAGE2E Gene

    110 amino acids
    Molecular mass:
    12217 Da
    Quaternary structure:
    No Data Available
    • This gene belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.
    • Sequence=CAI95421.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for GAGE2E Gene

Post-translational modifications for GAGE2E Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE2E Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GAGE2E Gene

Domains & Families for GAGE2E Gene

Gene Families for GAGE2E Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GAGE2E Gene


Suggested Antigen Peptide Sequences for GAGE2E Gene

GenScript: Design optimal peptide antigens:
  • G antigen 2E (GAG2E_HUMAN)

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GAGE family.
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE2E: view

Function for GAGE2E Gene

Phenotypes for GAGE2E Gene

GenomeRNAi human phenotypes for GAGE2E:
genes like me logo Genes that share phenotypes with GAGE2E: view

Animal Model Products

CRISPR Products

miRNA for GAGE2E Gene

miRTarBase miRNAs that target GAGE2E

Clone Products

  • Applied Biological Materials (abm): Clones for GAGE2E - Now 50% OFF >
  • * GAGE2E as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * GAGE2E tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GAGE2E Gene

Localization for GAGE2E Gene

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (1)
  • Golgi apparatus (1)
  • Plasma membrane (1)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GAGE2E Gene

Pathways & Interactions for GAGE2E Gene

PathCards logo

SuperPathways for GAGE2E Gene

No Data Available

Interacting Proteins for GAGE2E Gene

Selected Interacting proteins: Q4V326-GAG2E_HUMAN for GAGE2E Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for GAGE2E Gene


No data available for Pathways by source and SIGNOR curated interactions for GAGE2E Gene

Drugs & Compounds for GAGE2E Gene

No Compound Related Data Available

Transcripts for GAGE2E Gene

mRNA/cDNA for GAGE2E Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(29) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for GAGE2E Gene

G antigen 2E:
Representative Sequences:

CRISPR Products

Clone Products

  • Applied Biological Materials (abm): Clones for GAGE2E - Now 50% OFF >
  • * GAGE2E as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
  • * GAGE2E tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE2E Gene

No ASD Table

Relevant External Links for GAGE2E Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GAGE2E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GAGE2E Gene

mRNA differential expression in normal tissues according to GTEx for GAGE2E Gene

This gene is overexpressed in Testis (x52.2).

NURSA nuclear receptor signaling pathways regulating expression of GAGE2E Gene:


SOURCE GeneReport for Unigene cluster for GAGE2E Gene:


Evidence on tissue expression from TISSUES for GAGE2E Gene

  • Eye(2.4)
genes like me logo Genes that share expression patterns with GAGE2E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GAGE2E Gene

Orthologs for GAGE2E Gene

Evolution for GAGE2E Gene

Gene Tree for GAGE2E (if available)
Gene Tree for GAGE2E (if available)

No data available for Orthologs for GAGE2E Gene

Paralogs for GAGE2E Gene

(26) SIMAP similar genes for GAGE2E Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with GAGE2E: view

Variants for GAGE2E Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE2E Gene

Variant ID Type Subtype PubMed ID
esv3399100 CNV duplication 20981092
esv3408787 CNV duplication 20981092
nsv1129077 CNV duplication 24896259
nsv515202 CNV gain 21397061
nsv6897 CNV insertion 18451855

Additional Variant Information for GAGE2E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for GAGE2E Gene

Disorders for GAGE2E Gene

Additional Disease Information for GAGE2E

No disorders were found for GAGE2E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE2E Gene

Publications for GAGE2E Gene

  1. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff MF … Ditzel HJ (Tissue antigens 2008) 3 4 58
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 58
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual JF … Vidal M (Nature 2005) 3 58
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 58

Products for GAGE2E Gene

Sources for GAGE2E Gene

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