Aliases for GAGE12B Gene

Aliases for GAGE12B Gene

  • G Antigen 12B 2 3 5
  • G Antigen 12B/C/D/E 3 4
  • GAGE-12B 3 4
  • OTTHUMG00000024142 2
  • GAGE-12C 4
  • GAGE-12D 4
  • GAGE-12E 4
  • GAGE12B 5

External Ids for GAGE12B Gene

Previous GeneCards Identifiers for GAGE12B Gene

  • GC00U922119
  • GC0XP049116
  • GC0XP049196
  • GC0XP049187
  • GC0XP049188
  • GC0XP049316
  • GC0XP049318
  • GC0XP049295
  • GC0XP049529
  • GC0XP049343
  • GC0XP049349

Summaries for GAGE12B Gene

GeneCards Summary for GAGE12B Gene

GAGE12B (G Antigen 12B) is a Protein Coding gene.

Additional gene information for GAGE12B Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GAGE12B Gene

Genomics for GAGE12B Gene

Genomic Locations for GAGE12B Gene

Genomic Locations for GAGE12B Gene
188,803 bases
Plus strand
117 bases
Plus strand

Genomic View for GAGE12B Gene

Genes around GAGE12B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GAGE12B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GAGE12B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GAGE12B Gene

No data available for GeneHancer (GH) Regulatory Elements for GAGE12B Gene

Proteins for GAGE12B Gene

  • Protein details for GAGE12B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    G antigen 12B/C/D/E
    Protein Accession:
    Secondary Accessions:
    • A6NHF1
    • B7ZL74

    Protein attributes for GAGE12B Gene

    117 amino acids
    Molecular mass:
    12925 Da
    Quaternary structure:
    No Data Available
    • This gene belongs to a multigene family expressed in a large variety of tumors whereas in normal tissues, expression is restricted to germ cells. These genes organized in clustered repeats, have a high degree of predicted sequence identity, but differ by scattered single nucleotide substitution. Their sequences contain either the antigenic peptide YYWPRPRRY or YRPRPRRY which is recognized by cytotoxic T-cells.

neXtProt entry for GAGE12B Gene

Post-translational modifications for GAGE12B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GAGE12B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GAGE12B Gene

Domains & Families for GAGE12B Gene

Gene Families for GAGE12B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for GAGE12B Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GAGE family.
  • Belongs to the GAGE family.
genes like me logo Genes that share domains with GAGE12B: view

No data available for Suggested Antigen Peptide Sequences for GAGE12B Gene

Function for GAGE12B Gene

Gene Ontology (GO) - Molecular Function for GAGE12B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with GAGE12B: view

Animal Model Products

CRISPR Products

miRNA for GAGE12B Gene

miRTarBase miRNAs that target GAGE12B

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GAGE12B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GAGE12B Gene

Localization for GAGE12B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GAGE12B Gene

Pathways & Interactions for GAGE12B Gene

PathCards logo

SuperPathways for GAGE12B Gene

No Data Available

Interacting Proteins for GAGE12B Gene

Gene Ontology (GO) - Biological Process for GAGE12B Gene


No data available for Pathways by source and SIGNOR curated interactions for GAGE12B Gene

Drugs & Compounds for GAGE12B Gene

No Compound Related Data Available

Transcripts for GAGE12B Gene

mRNA/cDNA for GAGE12B Gene

3 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GAGE12B

Alternative Splicing Database (ASD) splice patterns (SP) for GAGE12B Gene

No ASD Table

Relevant External Links for GAGE12B Gene

GeneLoc Exon Structure for

Expression for GAGE12B Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GAGE12B Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GAGE12B

SOURCE GeneReport for Unigene cluster for GAGE12B Gene:

genes like me logo Genes that share expression patterns with GAGE12B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GAGE12B Gene

Orthologs for GAGE12B Gene

Evolution for GAGE12B Gene

Gene Tree for GAGE12B (if available)
Gene Tree for GAGE12B (if available)

No data available for Orthologs for GAGE12B Gene

Paralogs for GAGE12B Gene

(23) SIMAP similar genes for GAGE12B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with GAGE12B: view

No data available for Paralogs for GAGE12B Gene

Variants for GAGE12B Gene

Additional dbSNP identifiers (rs#s) for GAGE12B Gene

Structural Variations from Database of Genomic Variants (DGV) for GAGE12B Gene

Variant ID Type Subtype PubMed ID
dgv4237n106 CNV duplication 24896259
esv28941 CNV gain+loss 19812545
esv3363500 CNV duplication 20981092
esv3364710 CNV duplication 20981092
esv3373509 CNV duplication 20981092
esv3374855 CNV duplication 20981092
esv3393529 CNV duplication 20981092
esv3434123 CNV duplication 20981092
esv3435089 CNV duplication 20981092
esv3445396 CNV duplication 20981092
esv3446455 CNV duplication 20981092
esv3450031 CNV duplication 20981092
esv3451132 CNV duplication 20981092
nsv1075724 CNV deletion 25765185
nsv1075725 CNV deletion 25765185
nsv1076708 CNV duplication 25765185
nsv1129078 CNV duplication 24896259
nsv1141677 CNV duplication 24896259
nsv1151845 CNV duplication 26484159
nsv820429 CNV deletion 20802225
nsv953412 CNV duplication 24416366

Additional Variant Information for GAGE12B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for GAGE12B Gene

Disorders for GAGE12B Gene

Additional Disease Information for GAGE12B

No disorders were found for GAGE12B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GAGE12B Gene

Publications for GAGE12B Gene

  1. An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members. (PMID: 18179644) Gjerstorff MF … Ditzel HJ (Tissue antigens 2008) 3 4
  2. A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220. (PMID: 28625976) Hou P … Huang J (Cancer research 2017) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3
  4. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4

Products for GAGE12B Gene

Sources for GAGE12B Gene