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This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dep... See more...
Aliases for GADD45A Gene
Aliases for GADD45A Gene
External Ids for GADD45A Gene
- HGNC: 4095
- Entrez Gene: 1647
- Ensembl: ENSG00000116717
- OMIM: 126335
- UniProtKB: P24522
Previous HGNC Symbols for GADD45A Gene
- DDIT1
Previous GeneCards Identifiers for GADD45A Gene
- GC01P068111
- GC01P067082
- GC01P067508
- GC01P067520
- GC01P067862
- GC01P067923
- GC01P066261
Summaries for GADD45A Gene
-
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010]
GeneCards Summary for GADD45A Gene
GADD45A (Growth Arrest And DNA Damage Inducible Alpha) is a Protein Coding gene. Diseases associated with GADD45A include Ataxia-Telangiectasia and Colorectal Cancer. Among its related pathways are ATM Pathway and Transcriptional misregulation in cancer. Gene Ontology (GO) annotations related to this gene include core promoter binding. An important paralog of this gene is GADD45B.
UniProtKB/Swiss-Prot Summary for GADD45A Gene
-
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Additional gene information for GADD45A Gene
- HGNC(4095)
- Entrez Gene(1647)
- Ensembl(ENSG00000116717)
- OMIM(126335)
- UniProtKB(P24522)
- Open Targets Platform(ENSG00000116717)
- Monarch Initiative
- Search for GADD45A at DataMed
- Search for GADD45A at HumanCyc
No data available for Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for GADD45A Gene
Genomics for GADD45A Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for GADD45A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around GADD45A on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for GADD45A
- Top Transcription factor binding sites by QIAGEN in the GADD45A gene promoter:
-
- AP-1
- ATF-2
- c-Jun
- C/EBPbeta
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for GADD45A Gene
Genomic Locations for GADD45A Gene
- chr1:67,685,201-67,688,334
- (GRCh38/hg38)
- Size:
- 3,134 bases
- Orientation:
- Plus strand
- chr1:68,150,744-68,154,021
- (GRCh37/hg19)
- Size:
- 3,278 bases
- Orientation:
- Plus strand
Genomic View for GADD45A Gene
Genes around GADD45A on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p31.3 by HGNC
- 1p31.3 by Entrez Gene
- 1p31.3 by Ensembl
GADD45A Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GADD45A Gene
Proteins for GADD45A Gene
-
Protein details for GADD45A Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P24522-GA45A_HUMAN
- Recommended name:
- Growth arrest and DNA damage-inducible protein GADD45 alpha
- Protein Accession:
- P24522
- Q5TCA7
- Q5TCA8
Protein attributes for GADD45A Gene
- Size:
- 165 amino acids
- Molecular mass:
- 18336 Da
- Quaternary structure:
-
- Interacts with MAPK14 (By similarity). Predominantly monomeric but also forms dimers and other oligomers as concentration increases. Interacts with GADD45GIP1. Interacts weakly with PCNA. Interacts with AURKA, likely to compete with dimerization.
Post-translational modifications for GADD45A Gene
Other Protein References for GADD45A Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
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- antibodies-online: Show 20 available GADD45A Antibodies ranked by validation data
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- 22 WB Antibodies (anti-mouse)
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- 1 IF Antibody (anti-mouse)
- 76 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 2 IHC Antibodies (anti-human)
- 20 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
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Signalway ELISA kits for GADD45A
No data available for DME Specific Peptides for GADD45A Gene
Domains & Families for GADD45A Gene
Gene Families for GADD45A Gene
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Predicted intracellular proteins
Protein Domains for GADD45A Gene
- InterPro:
- Blocks:
-
- Ribosomal protein L7Ae/L30e/S12e/Gadd45
- ProtoNet:
Suggested Antigen Peptide Sequences for GADD45A Gene
- GenScript: Design optimal peptide antigens:
-
- Growth arrest and DNA-damage-inducible 45 alpha (A5JUZ3_HUMAN)
- DNA damage-inducible transcript 1 protein (GA45A_HUMAN)
- cDNA, FLJ95917, Homo sapiens growth arrest and DNA-damage-inducible, alpha(GADD45A), mRNA (Q5TCA8_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P24522- Family:
-
- Belongs to the GADD45 family.
Function for GADD45A Gene
Molecular function for GADD45A Gene
- UniProtKB/Swiss-Prot Function:
- In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
- UniProtKB/Swiss-Prot Induction:
- By UV irradiation, X-rays, growth arrest and alkylating agents. The induction is mediated by some kinase(s) other than PKC.
- GENATLAS Biochemistry:
- growth arrest and DNA-damage-inducible transcript alpha,involved in UV- and methyl methanisulfonate (MMS)-induced G2 arrest,p53-responsive stress protein activating MEKK4,interacting with the four core histones,mediating G2/M checkpoint,down-regulated by cyclin B1 and Cdc25C expression,inactivating (M phase promoting factor) MPF through interaction with CDC2 but not cyclin B1,putative downregulated c-Myc target gene,modifying DNA accessibility on damaged chromatin
Phenotypes From GWAS Catalog for GADD45A Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 12052864 |
| GO:0019900 | kinase binding | IPI | 20460379 |
| GO:0042803 | protein homodimerization activity | IDA | 20460379 |
| GO:0046982 | protein heterodimerization activity | IPI | 20460379 |
| GO:0047485 | protein N-terminus binding | IDA | 20460379 |
Phenotypes for GADD45A Gene
- MGI mutant phenotypes for GADD45A:
-
inferred from 1 alleles
- nervous system phenotype
- immune system phenotype
- cardiovascular system phenotype
- cellular phenotype
- mortality/aging
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- renal/urinary system phenotype
- neoplasm
- endocrine/exocrine gland phenotype
- reproductive system phenotype
- hematopoietic system phenotype
- integument phenotype
- embryo phenotype
- GenomeRNAi human phenotypes for GADD45A:
Animal Models for GADD45A Gene
- MGI Knock Outs for GADD45A:
-
- Gadd45a Gadd45a<tm1Ajf>
Animal Model Products
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CRISPR Products
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miRNA for GADD45A Gene
- miRTarBase miRNAs that target GADD45A
-
- hsa-miR-374a-5p (MIRT005574)
- mmu-miR-301b-3p (MIRT007793)
- mmu-miR-19b-3p (MIRT012344)
- hsa-miR-504-5p (MIRT016251)
- hsa-miR-26b-5p (MIRT029880)
- hsa-miR-615-3p (MIRT039859)
- rno-miR-499-5p (MIRT054059)
- hsa-miR-135b-3p (MIRT075723)
- hsa-miR-4678 (MIRT075736)
- hsa-miR-5681b (MIRT195818)
- hsa-miR-331-5p (MIRT195820)
- hsa-miR-4282 (MIRT195823)
- hsa-miR-3613-3p (MIRT195824)
- hsa-miR-148b-3p (MIRT260128)
- hsa-miR-607 (MIRT488304)
- hsa-miR-5701 (MIRT488305)
- rno-miR-1-3p (MIRT731614)
- hsa-miR-370-3p (MIRT732493)
- hsa-miR-34a-5p (MIRT733985)
miRNA Products
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Clone Products
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Cell Line Products
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Horizon Cell Lines for GADD45A
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for GADD45A Gene
Localization for GADD45A Gene
Subcellular locations from UniProtKB/Swiss-Prot for GADD45A Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 3 |
| cytosol | 3 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| endoplasmic reticulum | 2 |
| lysosome | 2 |
| peroxisome | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
- Nuclear speckles (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA,IDA | 9827804 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005737 | cytoplasm | IBA,IDA | 9827804 |
| GO:0016607 | nuclear speck | IDA | -- |
Pathways & Interactions for GADD45A Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Endometrial cancer |
.36
|
|
| 2 | Gastric cancer |
.62
.62
|
|
| 3 | Glioma |
.49
|
.46
|
| 4 | DNA Damage Response | ||
| 5 | Cell cycle |
.58
|
.58
|
Pathways by source for GADD45A Gene
2 Sino Biological pathways for GADD45A Gene
16 BioSystems pathways for GADD45A Gene
5 Reactome pathways for GADD45A Gene
1 PharmGKB pathway for GADD45A Gene
23 KEGG pathways for GADD45A Gene
1 GeneGo (Thomson Reuters) pathway for GADD45A Gene
- DNA damage_ATM/ATR regulation of G1/S checkpoint
5 Qiagen pathways for GADD45A Gene
- ATM Pathway
- BRCA1 Pathway
- DNA Repair Mechanisms
- GADD45 Pathway
- p53 Signaling
1 Cell Signaling Technology pathway for GADD45A Gene
2 GeneTex pathways for GADD45A Gene
Interacting Proteins for GADD45A Gene
Selected Interacting proteins:
P24522-GA45A_HUMAN
ENSP00000360025
for GADD45A Gene via
UniProtKB
MINT
STRING
IID
| Symbol | External ID(s) | Details |
|---|---|---|
| AICDA | ||
| DCTN2 | ||
| GADD45GIP1 | ||
| MAP2K6 | ||
| RBPJ |
GPS-Prot Interaction Network for GADD45A
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity | TAS | 10747892 |
| GO:0000122 | negative regulation of transcription by RNA polymerase II | IMP | 23329839 |
| GO:0000185 | activation of MAPKKK activity | IDA | 9827804 |
| GO:0006281 | DNA repair | TAS | 7973727 |
| GO:0006469 | negative regulation of protein kinase activity | IEA | -- |
Transcripts for GADD45A Gene
mRNA/cDNA for GADD45A Gene
- 3 REFSEQ mRNAs :
- 7 NCBI additional mRNA sequence :
- 7 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000370985 902 nts (view in UCSC)
- ENST00000370986 1352 nts (view in UCSC)
- ENST00000460575 874 nts (view in UCSC)
- ENST00000484245 688 nts (view in UCSC)
- ENST00000617962 1093 nts (view in UCSC)
CRISPR Products
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-
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Clone Products
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- Sino Biological Human cDNA Clone for GADD45A
- Addgene plasmids for GADD45A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GADD45A
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||
| SP2: | - | - | |||||||||||||
| SP3: |
Relevant External Links for GADD45A Gene
- GeneLoc Exon Structure for
- GADD45A
Expression for GADD45A Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Gonad (Reproductive System)
- Primordial Germ Cells Primitive Gonad
- Primordial Germ Cells Allantois
-
Eye (Sensory Organs)
- Mature Rod Cells Outer Nuclear Layer
-
Neurons
- Mature Rod Cells Outer Nuclear Layer
-
Placenta (Extraembryonic Tissues)
- Primordial Germ Cells Allantois
- Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for GADD45A Gene
This gene is overexpressed in Muscle - Skeletal (x4.3).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for GADD45A
SOURCE GeneReport for Unigene cluster for GADD45A Gene:
Hs.80409Evidence on tissue expression from TISSUES for GADD45A Gene
- Muscle(4.7)
- Lung(4.6)
- Kidney(3.5)
- Nervous system(3.4)
- Liver(3.4)
- Heart(3.2)
- Intestine(3.1)
- Spleen(2.9)
- Bone marrow(2.9)
- Skin(2.8)
- Blood(2.7)
- Thyroid gland(2.6)
- Stomach(2.4)
- Eye(2.4)
- Lymph node(2.2)
- Pancreas(2.2)
- Adrenal gland(2.1)
Primer Products
-
OriGene qPCR primer pairs for GADD45A
-
OriGene qPCR primer pairs and template standards for GADD45A
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for GADD45A Gene
Orthologs for GADD45A Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | GADD45A 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | GADD45A 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | GADD45A 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Gadd45a 30 17 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | GADD45A 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Gadd45a 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | GADD45A 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | GADD45 31 |
|
OneToOne | |
| GADD45A 30 |
|
||||
| Lizard (Anolis carolinensis) |
Reptilia | GADD45A 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | gadd45a 30 |
|
||
| Str.1971 30 |
|
||||
| Zebrafish (Danio rerio) |
Actinopterygii | gadd45aa 31 |
|
OneToMany | |
| gadd45ab 30 31 |
|
OneToMany | |||
| Dr.14374 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.4328 30 |
|
- Species where no ortholog for GADD45A was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for GADD45A Gene
- ENSEMBL:
- Gene Tree for GADD45A (if available)
- TreeFam:
- Gene Tree for GADD45A (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for GADD45A: view image
Paralogs for GADD45A Gene
Variants for GADD45A Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for GADD45A Gene
| SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 784441 | Benign: not provided | 67,686,488(+) | G/A | SYNONYMOUS_VARIANT,INTRON_VARIANT |
Residual Variation Intolerance Score:
38.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.07;
1.62% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for GADD45A Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GADD45A Gene
Disorders for GADD45A Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ataxia-telangiectasia |
|
|
| colorectal cancer |
|
|
| xeroderma pigmentosum, variant type |
|
|
| pancreatic cancer |
|
|
| lung cancer |
|
Search GADD45A in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for GADD45A
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for GADD45A Gene
Publications for GADD45A Gene
- Induction by ionizing radiation of the gadd45 gene in cultured human cells: lack of mediation by protein kinase C. (PMID: 1990262) Papathanasiou MA … Fornace AJ (Molecular and cellular biology 1991) 2 3 4 23
- Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen. (PMID: 7973727) Smith ML … Fornace AJ (Science (New York, N.Y.) 1994) 3 4 23
- Analysis of the mammalian gadd45 gene and its response to DNA damage. (PMID: 8226988) Hollander MC … Fornace AJ (The Journal of biological chemistry 1993) 2 3 4
- GADD45A binds R-loops and recruits TET1 to CpG island promoters. (PMID: 30617255) Arab K … Niehrs C (Nature genetics 2019) 2 3
- Solution structure of human growth arrest and DNA damage 45alpha (Gadd45alpha) and its interactions with proliferating cell nuclear antigen (PCNA) and Aurora A kinase. (PMID: 20460379) Sánchez R … Blanco FJ (The Journal of biological chemistry 2010) 3 4
ExternalLinks
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- VectorBuilder Viral vectors for GADD45A (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for GADD45A (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for GADD45A CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for GADD45A
- Addgene plasmids for GADD45A
- antibodies-online: Show 20 available GADD45A Antibodies ranked by validation data
- Compare Top GADD45A Antibodies
- Recommended
- 22 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 1 IF Antibody (anti-mouse)
- 76 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 2 IF Antibodies (anti-human)
- 2 IHC Antibodies (anti-human)
- 20 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- antibodies-online: Show 13 available GADD45A Elisa Kits ranked by validation data
- Compare Top GADD45A Elisa Kits
- antibodies-online: Show 17 available GADD45A Proteins ranked by validation data
- Compare Top GADD45A Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for GADD45A
- Search Santa Cruz Biotechnology (SCBT) for GADD45A siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for GADD45A
- Search for GADD45A Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for GADD45A
- Horizon Cell Lines for GADD45A
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for GADD45A
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for GADD45A
- Search GeneCopoeia for miRNA 3'UTR Target clone products for GADD45A
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for GADD45A
Sources for GADD45A Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB