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Aliases for GACAT3 Gene

Subcategory (RNA class) for GACAT3 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for GACAT3 Gene

  • Gastric Cancer Associated Transcript 3 2 3 5
  • Gastric Cancer Associated Transcript 3 (Non-Protein Coding) 2 3
  • Long Intergenic Non-Protein Coding RNA 1458 2 3
  • LncRNA-AC130710 3
  • LINC01458 3

External Ids for GACAT3 Gene

Previous HGNC Symbols for GACAT3 Gene

  • LINC01458

Summaries for GACAT3 Gene

GeneCards Summary for GACAT3 Gene

GACAT3 (Gastric Cancer Associated Transcript 3) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with GACAT3 include Gastric Cancer and Ovarian Cancer.

Additional gene information for GACAT3 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GACAT3 Gene

Genomics for GACAT3 Gene

GeneHancer (GH) Regulatory Elements for GACAT3 Gene

Promoters and enhancers for GACAT3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02J016012 Enhancer 0.8 FANTOM5 ENCODE 600.7 -0.7 -701 1.9 MYC ZNF512B POLR2A ZNF217 DPF2 CTCF SMARCE1 GACAT3 NBAS ENSG00000226764 RN7SL104P GC02M015984
GH02J016005 Enhancer 1 Ensembl ENCODE 0.4 -7.7 -7727 2.8 ELF3 CEBPG AHR TFE3 SP1 ZNF384 ZNF644 RXRA CEBPA GATAD2A GACAT3 ENSG00000226764 RN7SL104P GC02M015984
GH02J016051 Enhancer 1 Ensembl ENCODE dbSUPER 0.3 +36.6 36573 2.6 PPARG FOXA2 CREM TFAP4 NFIL3 BCL6 SMAD4 KDM1A TEAD3 ELF1 ENSG00000226764 GACAT3 GC02M015984
GH02J016067 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.2 +55.7 55691 3.5 ELF3 CEBPG RERE ZNF24 MAFK SP5 ZNF384 ZNF644 KAT8 HMG20B ENSG00000226764 ENSG00000236989 GACAT3 GC02M015984
GH02J016029 Enhancer 0.7 Ensembl dbSUPER 0.4 +17.3 17333 2.3 RXRA FOXA2 KLF4 RAD21 HNF4A BCL6 FOXA1 GACAT3 ENSG00000226764 GC02M015984
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around GACAT3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GACAT3 Gene

Genomic Locations for GACAT3 Gene
chr2:16,013,928-16,086,307
(GRCh38/hg38)
Size:
72,380 bases
Orientation:
Plus strand
chr2:16,190,549-16,225,923
(GRCh37/hg19)
Size:
35,375 bases
Orientation:
Plus strand

Genomic View for GACAT3 Gene

Genes around GACAT3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GACAT3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GACAT3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GACAT3 Gene

Proteins for GACAT3 Gene

Post-translational modifications for GACAT3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for GACAT3 Gene

Domains & Families for GACAT3 Gene

Gene Families for GACAT3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GACAT3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GACAT3 Gene

Function for GACAT3 Gene

Phenotypes From GWAS Catalog for GACAT3 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GACAT3 Gene

Localization for GACAT3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for GACAT3 Gene

Pathways & Interactions for GACAT3 Gene

PathCards logo

SuperPathways for GACAT3 Gene

No Data Available

Interacting Proteins for GACAT3 Gene

Gene Ontology (GO) - Biological Process for GACAT3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GACAT3 Gene

Drugs & Compounds for GACAT3 Gene

No Compound Related Data Available

Transcripts for GACAT3 Gene

mRNA/cDNA for GACAT3 Gene

(2) Additional mRNA sequences :
(7) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
(3) RNA Central transcripts :

Alternative Splicing Database (ASD) splice patterns (SP) for GACAT3 Gene

No ASD Table

Relevant External Links for GACAT3 Gene

GeneLoc Exon Structure for
GACAT3
ECgene alternative splicing isoforms for
GACAT3

Expression for GACAT3 Gene

NURSA nuclear receptor signaling pathways regulating expression of GACAT3 Gene:

GACAT3
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GACAT3 Gene

Orthologs for GACAT3 Gene

Evolution for GACAT3 Gene

ENSEMBL:
Gene Tree for GACAT3 (if available)
TreeFam:
Gene Tree for GACAT3 (if available)

No data available for Orthologs for GACAT3 Gene

Paralogs for GACAT3 Gene

No data available for Paralogs for GACAT3 Gene

Variants for GACAT3 Gene

Sequence variations from dbSNP and Humsavar for GACAT3 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000000911 -- 16,064,681(+) T/C intron_variant
rs1000033498 -- 16,065,004(+) G/A intron_variant
rs1000035853 -- 16,080,237(+) A/G intron_variant
rs1000133649 -- 16,049,879(+) G/A upstream_transcript_variant
rs1000184420 -- 16,076,744(+) C/T intron_variant

Additional Variant Information for GACAT3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GACAT3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for GACAT3 Gene

Disorders for GACAT3 Gene

MalaCards: The human disease database

(2) MalaCards diseases for GACAT3 Gene - From: LncRNADisease, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
gastric cancer
  • gastric cancer, somatic
ovarian cancer
  • ovarian cancer, somatic
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for GACAT3

genes like me logo Genes that share disorders with GACAT3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for GACAT3 Gene

Publications for GACAT3 Gene

  1. lncRNA-AC130710 targeting by miR-129-5p is upregulated in gastric cancer and associates with poor prognosis. (PMID: 24969565) Xu C … Guo J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014) 2 3 58
  2. Long noncoding RNA HMlincRNA717 and AC130710 have been officially named as gastric cancer associated transcript 2 (GACAT2) and GACAT3, respectively. (PMID: 25077925) Chen S … Guo J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014) 2 3 58
  3. LncRNA GACAT3 promotes gastric cancer progression by negatively regulating miR-497 expression. (PMID: 29091858) Feng L … Rao M (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018) 3 58
  4. LncRNA GACAT3 predicts poor prognosis and promotes cell proliferation in breast cancer through regulation of miR-497/CCND2. (PMID: 29945347) Zhong H … Wang C (Cancer biomarkers : section A of Disease markers 2018) 3 58
  5. LncRNA GACAT3 acts as a competing endogenous RNA of HMGA1 and alleviates cucurbitacin B-induced apoptosis of gastric cancer cells. (PMID: 30098426) Lin Y … Qiu X (Gene 2018) 3 58

Products for GACAT3 Gene

Sources for GACAT3 Gene

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