Aliases for GABRR1 Gene
- Gamma-Aminobutyric Acid Type A Receptor Rho1 Subunit 2 3 5
- Gamma-Aminobutyric Acid (GABA) Receptor, Rho 1 2 3
- GABA(A) Receptor Subunit Rho-1 3 4
- GABA(A) Receptor, Rho 1 2 3
- GABA(C) Receptor 3 4
- BA135P14.1 (Gamma-Aminobutyric Acid (GABA) Receptor, Rho 1) 3
- Gamma-Aminobutyric Acid (GABA) A Receptor, Rho-1 3
- Gamma-Aminobutyric Acid (GABA) A Receptor, Rho 1 2
- Gamma-Aminobutyric Acid Receptor Subunit Rho-1 3
External Ids for GABRR1 Gene
Previous GeneCards Identifiers for GABRR1 Gene
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
GeneCards Summary for GABRR1 Gene
GABRR1 (Gamma-Aminobutyric Acid Type A Receptor Rho1 Subunit) is a Protein Coding gene. Among its related pathways are GABA receptor activation and Transmission across Chemical Synapses. Gene Ontology (GO) annotations related to this gene include chloride channel activity and GABA-A receptor activity. An important paralog of this gene is GABRR2.
UniProtKB/Swiss-Prot for GABRR1 Gene
GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission.
GABAA-rho receptors, previously known as GABAC receptors, are Cys-loop ionotropic ligand-gated ion channels mediating the fast synaptic inhibitory effects of GABA. Despite differing in pharmacology, physiology and biochemistry, they are viewed as a subclass of GABAA receptors.