Aliases for GABARAPL1 Gene
External Ids for GABARAPL1 Gene
Previous GeneCards Identifiers for GABARAPL1 Gene
GeneCards Summary for GABARAPL1 Gene
GABARAPL1 (GABA Type A Receptor Associated Protein Like 1) is a Protein Coding gene. Diseases associated with GABARAPL1 include Amyotrophic Lateral Sclerosis Type 14 and Nemaline Myopathy 1. Among its related pathways are Cellular Senescence (REACTOME) and NOD-like receptor signaling pathway. Gene Ontology (GO) annotations related to this gene include microtubule binding and GABA receptor binding. An important paralog of this gene is GABARAP.
UniProtKB/Swiss-Prot Summary for GABARAPL1 Gene
Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.