Aliases for FXYD2 Gene
External Ids for FXYD2 Gene
Previous HGNC Symbols for FXYD2 Gene
Previous GeneCards Identifiers for FXYD2 Gene
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes the sodium/potassium-transporting ATPase subunit gamma. Mutations in this gene have been associated with Renal Hypomagnesemia-2. Alternatively spliced transcript variants have been described. Read-through transcripts have been observed between this locus and the upstream FXYD domain-containing ion transport regulator 6 (FXYD6, GeneID 53826) locus.[provided by RefSeq, Feb 2011]
GeneCards Summary for FXYD2 Gene
FXYD2 (FXYD Domain Containing Ion Transport Regulator 2) is a Protein Coding gene. Diseases associated with FXYD2 include Hypomagnesemia 2, Renal and Primary Hypomagnesemia. Among its related pathways are Collagen chain trimerization and Cardiac muscle contraction. Gene Ontology (GO) annotations related to this gene include transporter activity and sodium channel regulator activity. An important paralog of this gene is FXYD6-FXYD2.
UniProtKB/Swiss-Prot Summary for FXYD2 Gene
May be involved in forming the receptor site for cardiac glycoside binding or may modulate the transport function of the sodium ATPase.