The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] See more...

Aliases for FXR1 Gene

Aliases for FXR1 Gene

  • FMR1 Autosomal Homolog 1 2 3 5
  • Fragile X Mental Retardation Syndrome-Related Protein 1 3 4
  • Fragile X Mental Retardation, Autosomal Homolog 1 2 3
  • MYOPMIL 3
  • MYORIBF 3
  • HFXR1p 4
  • FXR1P 3
  • FXR1 5

External Ids for FXR1 Gene

Previous GeneCards Identifiers for FXR1 Gene

  • GC03P177391
  • GC03P181474
  • GC03P182032
  • GC03P181951
  • GC03P182113
  • GC03P180585
  • GC03P178034

Summaries for FXR1 Gene

Entrez Gene Summary for FXR1 Gene

  • The protein encoded by this gene is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

GeneCards Summary for FXR1 Gene

FXR1 (FMR1 Autosomal Homolog 1) is a Protein Coding gene. Diseases associated with FXR1 include Myopathy, Congenital, With Respiratory Insufficiency And Bone Fractures and Myopathy, Congenital Proximal, With Minicore Lesions. Among its related pathways are RNA transport and Translational Control. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and RNA binding. An important paralog of this gene is FXR2.

UniProtKB/Swiss-Prot Summary for FXR1 Gene

  • RNA-binding protein required for embryonic and postnatal development of muscle tissue (PubMed:30770808). May regulate intracellular transport and local translation of certain mRNAs (By similarity).

Gene Wiki entry for FXR1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FXR1 Gene

Genomics for FXR1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FXR1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J180910 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 250.3 +45.0 44999 4.5 BCLAF1 ZNF207 POLR2A NFIC ZIC2 ZBTB10 YY1 CTCF SMAD5 SIN3A NONHSAG036778.2 FXR1 DNAJC19 ENSG00000242068 CCDC39 HSALNG0031025
GH03J180870 Promoter/Enhancer 1.1 Ensembl ENCODE 0.7 +2.8 2822 3.5 POLR2A ZNF316 NFE2 TAF1 L3MBTL2 ZNF680 CBX3 MGA EMSY E2F1 LOC101928882 piR-35581 CCDC39 ENSG00000242068 FXR1 LOC105374240 lnc-TTC14-3 DNAJC19
GH03J180988 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.1 +121.5 121460 2.8 SP1 ZNF207 MYC IKZF1 ZNF600 POLR2A CEBPA ATF3 BRCA1 YY1 DNAJC19 SOX2-OT lnc-DNAJC19-5 TTC14 ENSG00000242068 lnc-TTC14-1 FXR1
GH03J180855 Enhancer 0.6 Ensembl ENCODE 0.4 -12.8 -12809 0.7 CTCF RAD21 TRIM22 FXR1 LOC105374240 LOC101928882 FLYWCH1P1 CCDC39
GH03J181289 Enhancer 0.2 FANTOM5 1.2 +421.8 421783 0.3 SOX2 DNAJC19 FXR1 HSALNG0031037 hsa-miR-5095-355 JN711430 SOX2-OT
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FXR1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FXR1

Top Transcription factor binding sites by QIAGEN in the FXR1 gene promoter:
  • Arnt
  • ATF6
  • COMP1
  • GR
  • GR-alpha
  • RP58
  • SREBP-1a
  • SREBP-1b
  • SREBP-1c
  • USF2

Genomic Locations for FXR1 Gene

Latest Assembly
chr3:180,868,141-180,982,753
(GRCh38/hg38)
Size:
114,613 bases
Orientation:
Plus strand

Previous Assembly
chr3:180,630,458-180,700,541
(GRCh37/hg19 by Entrez Gene)
Size:
70,084 bases
Orientation:
Plus strand

chr3:180,585,929-180,700,541
(GRCh37/hg19 by Ensembl)
Size:
114,613 bases
Orientation:
Plus strand

Genomic View for FXR1 Gene

Genes around FXR1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FXR1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FXR1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FXR1 Gene

Proteins for FXR1 Gene

  • Protein details for FXR1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51114-FXR1_HUMAN
    Recommended name:
    Fragile X mental retardation syndrome-related protein 1
    Protein Accession:
    P51114
    Secondary Accessions:
    • A8K9B8
    • Q7Z450
    • Q8N6R8

    Protein attributes for FXR1 Gene

    Size:
    621 amino acids
    Molecular mass:
    69721 Da
    Quaternary structure:
    • Interacts with FMR1 (PubMed:8668200, PubMed:7489725, PubMed:11157796). Interacts with FRX2 (PubMed:7489725). Interacts with TDRD3 (PubMed:18664458). Interacts with HABP4 (PubMed:21771594). Interacts with CYFIP2 but not with CYFIP1 (By similarity).
    • (Microbial infection) Interacts with Sindbis virus non-structural protein 3 (via C-terminus); this interaction inhibits the formation of host stress granules on viral mRNAs and the nsp3-FXR1 complexes bind viral RNAs and probably orchestrate the assembly of viral replication complexes.

    Three dimensional structures from OCA and Proteopedia for FXR1 Gene

    Alternative splice isoforms for FXR1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FXR1 Gene

Post-translational modifications for FXR1 Gene

  • Arg-445 is dimethylated, probably to asymmetric dimethylarginine.
  • Ubiquitination at Lys179, Lys207, and Lys246
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for FXR1 Gene

Domains & Families for FXR1 Gene

Gene Families for FXR1 Gene

Human Protein Atlas (HPA):
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for FXR1 Gene

Suggested Antigen Peptide Sequences for FXR1 Gene

GenScript: Design optimal peptide antigens:
  • cDNA FLJ58644, highly similar to Fragile X mental retardation syndrome-related protein 1 (B4DXZ6_HUMAN)
  • Fragile X mental retardation syndrome-related protein 1 (FXR1_HUMAN)
  • FXR1 protein (Q14341_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P51114

UniProtKB/Swiss-Prot:

FXR1_HUMAN :
  • The tandem Agenet-like domains preferentially recognize trimethylated histone peptides.
  • Belongs to the FMR1 family.
Domain:
  • The tandem Agenet-like domains preferentially recognize trimethylated histone peptides.
Family:
  • Belongs to the FMR1 family.
genes like me logo Genes that share domains with FXR1: view

Function for FXR1 Gene

Molecular function for FXR1 Gene

UniProtKB/Swiss-Prot Function:
RNA-binding protein required for embryonic and postnatal development of muscle tissue (PubMed:30770808). May regulate intracellular transport and local translation of certain mRNAs (By similarity).
GENATLAS Biochemistry:
cytoplasmic RNA binding protein (70kDa) homologous to FMR1 and FXR2 (see symbols),homodimerizing and heterodimerizing with them,expressed in fetal and adult brain testis,putative target for the autoimmune response,with several alternatively spliced isoforms

Phenotypes From GWAS Catalog for FXR1 Gene

Gene Ontology (GO) - Molecular Function for FXR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0003723 RNA binding IEA,HDA 22658674
GO:0003729 mRNA binding IEA --
GO:0003730 mRNA 3'-UTR binding IBA 21873635
GO:0005515 protein binding IPI 7489725
genes like me logo Genes that share ontologies with FXR1: view
genes like me logo Genes that share phenotypes with FXR1: view

Human Phenotype Ontology for FXR1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for FXR1 Gene

MGI Knock Outs for FXR1:
  • Fxr1 Fxr1<tm1.2Dln>
  • Fxr1 Fxr1<tm1Drad>

miRNA for FXR1 Gene

miRTarBase miRNAs that target FXR1

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FXR1

Clone products for research

  • Addgene plasmids for FXR1

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for FXR1 Gene

Localization for FXR1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FXR1 Gene

Cytoplasm, cytosol. Note=Adjacent to Z-lines in muscles. {ECO:0000250 UniProtKB:Q61584}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FXR1 gene
Compartment Confidence
nucleus 5
cytosol 5
cytoskeleton 2
mitochondrion 2
plasma membrane 1
extracellular 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for FXR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
GO:0005730 nucleolus TAS 10888599
GO:0005737 cytoplasm IEA,IMP 30770808
GO:0005829 cytosol IDA 30770808
GO:0005844 polysome TAS,IBA 21873635
genes like me logo Genes that share ontologies with FXR1: view

Pathways & Interactions for FXR1 Gene

genes like me logo Genes that share pathways with FXR1: view

Pathways by source for FXR1 Gene

2 Cell Signaling Technology pathways for FXR1 Gene

Gene Ontology (GO) - Biological Process for FXR1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000381 regulation of alternative mRNA splicing, via spliceosome IBA 21873635
GO:0001934 positive regulation of protein phosphorylation IBA 21873635
GO:0006417 regulation of translation IEA --
GO:0006915 apoptotic process TAS 9642279
GO:0007275 multicellular organism development IEA --
genes like me logo Genes that share ontologies with FXR1: view

No data available for SIGNOR curated interactions for FXR1 Gene

Drugs & Compounds for FXR1 Gene

No Compound Related Data Available

Transcripts for FXR1 Gene

mRNA/cDNA for FXR1 Gene

4 REFSEQ mRNAs :
21 NCBI additional mRNA sequence :
22 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FXR1

Clone products for research

  • Addgene plasmids for FXR1

Alternative Splicing Database (ASD) splice patterns (SP) for FXR1 Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b ^ 16a · 16b ^ 17a ·
SP1: -
SP2: -
SP3: -
SP4: - -
SP5: -
SP6: - - -
SP7: - -
SP8: - -
SP9:
SP10: - -
SP11:
SP12: -
SP13: -

ExUns: 17b ^ 18a · 18b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10: -
SP11:
SP12:
SP13:

Relevant External Links for FXR1 Gene

GeneLoc Exon Structure for
FXR1

Expression for FXR1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FXR1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FXR1 Gene

This gene is overexpressed in Muscle - Skeletal (x8.1).

Protein differential expression in normal tissues from HIPED for FXR1 Gene

This gene is overexpressed in Lung (27.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FXR1 Gene



Protein tissue co-expression partners for FXR1 Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FXR1

SOURCE GeneReport for Unigene cluster for FXR1 Gene:

Hs.478407

mRNA Expression by UniProt/SwissProt for FXR1 Gene:

P51114-FXR1_HUMAN
Tissue specificity: Expressed in all tissues examined including heart, brain, kidney and testis.

Evidence on tissue expression from TISSUES for FXR1 Gene

  • Nervous system(5)
  • Liver(4.5)
  • Muscle(3.4)
  • Heart(3.1)
  • Lung(3)
  • Kidney(2.8)
  • Skin(2.5)
  • Spleen(2.3)
  • Bone marrow(2.2)
  • Intestine(2.2)
  • Adrenal gland(2.1)
  • Lymph node(2.1)
genes like me logo Genes that share expression patterns with FXR1: view

Primer products for research

No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for FXR1 Gene

Orthologs for FXR1 Gene

This gene was present in the common ancestor of animals.

Orthologs for FXR1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia FXR1 29 30
  • 99.89 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia FXR1 29 30
  • 96.56 (n)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia FXR1 30
  • 96 (a)
OneToOne
Dog
(Canis familiaris)
Mammalia FXR1 29 30
  • 95.97 (n)
OneToOne
Mouse
(Mus musculus)
Mammalia Fxr1 29 16 30
  • 94.95 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Fxr1 29
  • 94.62 (n)
Oppossum
(Monodelphis domestica)
Mammalia FXR1 30
  • 88 (a)
OneToOne
Chicken
(Gallus gallus)
Aves FXR1 29 30
  • 82.93 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia FXR1 30
  • 83 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia fxr1 29
  • 79.45 (n)
Str.6155 29
Zebrafish
(Danio rerio)
Actinopterygii fxr1 29 30
  • 68.74 (n)
OneToOne
wufd18c10 29
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10011 29
Fruit Fly
(Drosophila melanogaster)
Insecta Fmr1 30 31
  • 31 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 48 (a)
OneToMany
Species where no ortholog for FXR1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for FXR1 Gene

ENSEMBL:
Gene Tree for FXR1 (if available)
TreeFam:
Gene Tree for FXR1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for FXR1: view image
Alliance of Genome Resources:
Additional Orthologs for FXR1

Paralogs for FXR1 Gene

Paralogs for FXR1 Gene

(2) SIMAP similar genes for FXR1 Gene using alignment to 12 proteins:

  • FXR1_HUMAN
  • B4DXZ6_HUMAN
  • C9IZ22_HUMAN
  • C9J5B4_HUMAN
  • C9JAJ4_HUMAN
  • C9JY20_HUMAN
  • C9JYQ6_HUMAN
  • C9JZE0_HUMAN
  • E7EU85_HUMAN
  • E9PFF5_HUMAN
  • H7C4S4_HUMAN
  • Q14341_HUMAN

Pseudogenes.org Pseudogenes for FXR1 Gene

genes like me logo Genes that share paralogs with FXR1: view

Variants for FXR1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FXR1 Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
986379 Uncertain Significance: Congenital myopathy 180,947,913(+) A/G
NM_005087.4(FXR1):c.247A>G (p.Lys83Glu)
MISSENSE_VARIANT,FIVE_PRIME_UTR
986381 Uncertain Significance: Congenital myopathy 180,948,422(+) A/G
NM_005087.4(FXR1):c.346A>G (p.Asn116Asp)
MISSENSE
996580 Likely Pathogenic: Intellectual disability 180,976,198(+) T/A
NM_005087.4(FXR1):c.1772T>A (p.Ile591Asn)
MISSENSE_VARIANT,THREE_PRIME_UTR
rs1577005361 Pathogenic: Myopathy, congenital, with respiratory insufficiency and bone fractures 180,971,145(+) TAGAC/T
NM_005087.4(FXR1):c.1603+790_1603+793del
INTRON
rs1805578 Benign: not provided 180,912,712(+) C/T
NM_005087.4(FXR1):c.27C>T (p.Arg9=)
SYNONYMOUS_VARIANT,FIVE_PRIME_UTR

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for FXR1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for FXR1 Gene

Variant ID Type Subtype PubMed ID
esv3598875 CNV gain 21293372
esv3598878 CNV loss 21293372
esv3598879 CNV gain 21293372
nsv1147853 CNV insertion 26484159

Variation tolerance for FXR1 Gene

Residual Variation Intolerance Score: 10.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.01; 20.79% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FXR1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FXR1
Leiden Open Variation Database (LOVD)
FXR1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FXR1 Gene

Disorders for FXR1 Gene

MalaCards: The human disease database

(13) MalaCards diseases for FXR1 Gene - From: OMI, CVR, COP, and GCD

- elite association - COSMIC cancer census association via MalaCards
Search FXR1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

FXR1_HUMAN
  • Myopathy, congenital, with respiratory insufficiency and bone fractures (MYORIBF) [MIM:618822]: An autosomal recessive muscular disorder characterized by severe hypotonia apparent at birth, poor feeding, ulnar deviation of the hands, laterally deviated feet, fractures of the long bones, respiratory insufficiency due to muscle weakness, and death in infancy. {ECO:0000269 PubMed:30770808}. Note=The disease is caused by variants affecting the gene represented in this entry.
  • Myopathy, congenital proximal, with minicore lesions (MYOPMIL) [MIM:618823]: An autosomal recessive, slowly progressive muscular disorder characterized by primarily proximal muscle weakness, neonatal hypotonia leading to delayed motor development, mildly delayed walking in childhood, and difficulty running or climbing. Cardiac function is unaffected, but most patients have obstructive sleep apnea. Muscle biopsy shows type 1 fiber predominance with disorganized Z-lines and minicores that disrupt the myofibrillar striation pattern. {ECO:0000269 PubMed:30770808}. Note=The disease is caused by variants affecting the gene represented in this entry.

Additional Disease Information for FXR1

genes like me logo Genes that share disorders with FXR1: view

No data available for Genatlas for FXR1 Gene

Publications for FXR1 Gene

  1. FXR1, an autosomal homolog of the fragile X mental retardation gene. (PMID: 7781595) Siomi MC … Dreyfuss G (The EMBO journal 1995) 2 3 4 22
  2. Recessive mutations in muscle-specific isoforms of FXR1 cause congenital multi-minicore myopathy. (PMID: 30770808) Estañ MC … Ruiz-Perez VL (Nature communications 2019) 3 4 72
  3. Evidence that fragile X mental retardation protein is a negative regulator of translation. (PMID: 11157796) Laggerbauer B … Fischer U (Human molecular genetics 2001) 3 4 22
  4. The fragile-X-related gene FXR1 is a human autoantigen processed during apoptosis. (PMID: 9642279) Bolívar J … Valdivia MM (The Journal of biological chemistry 1998) 2 3 22
  5. Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them. (PMID: 8668200) Siomi MC … Dreyfuss G (Molecular and cellular biology 1996) 3 4 22

Products for FXR1 Gene

Sources for FXR1 Gene