Aliases for FUT4 Gene
External Ids for FUT4 Gene
Previous HGNC Symbols for FUT4 Gene
Previous GeneCards Identifiers for FUT4 Gene
The product of this gene transfers fucose to N-acetyllactosamine polysaccharides to generate fucosylated carbohydrate structures. It catalyzes the synthesis of the non-sialylated antigen, Lewis x (CD15). [provided by RefSeq, Jan 2009]
GeneCards Summary for FUT4 Gene
FUT4 (Fucosyltransferase 4) is a Protein Coding gene. Diseases associated with FUT4 include Colon Adenocarcinoma and Liver Lymphoma. Among its related pathways are Wnt / Hedgehog / Notch and Mannose type O-glycan biosynthesis. Gene Ontology (GO) annotations related to this gene include fucosyltransferase activity and alpha-(1->3)-fucosyltransferase activity. An important paralog of this gene is FUT7.
UniProtKB/Swiss-Prot for FUT4 Gene
May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens.