Aliases for FSTL1 Gene
External Ids for FSTL1 Gene
Previous GeneCards Identifiers for FSTL1 Gene
This gene encodes a protein with similarity to follistatin, an activin-binding protein. It contains an FS module, a follistatin-like sequence containing 10 conserved cysteine residues. This gene product is thought to be an autoantigen associated with rheumatoid arthritis. [provided by RefSeq, Jul 2008]
GeneCards Summary for FSTL1 Gene
FSTL1 (Follistatin Like 1) is a Protein Coding gene. Diseases associated with FSTL1 include Rheumatoid Arthritis and Arthritis. Among its related pathways are Signaling by GPCR and Signaling by BMP. Gene Ontology (GO) annotations related to this gene include calcium ion binding and heparin binding. An important paralog of this gene is FSTL4.
UniProtKB/Swiss-Prot Summary for FSTL1 Gene
Promotes endothelial cell survival, migration and differentiation into network structures in an AKT-dependent manner. Also promotes survival of cardiac myocytes.