Free for academic non-profit institutions. Other users need a Commercial license
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergi... See more...
Aliases for FOXJ1 Gene
Aliases for FOXJ1 Gene
External Ids for FOXJ1 Gene
- HGNC: 3816
- Entrez Gene: 2302
- Ensembl: ENSG00000129654
- OMIM: 602291
- UniProtKB: Q92949
Previous HGNC Symbols for FOXJ1 Gene
- FKHL13
Previous GeneCards Identifiers for FOXJ1 Gene
- GC17M073990
- GC17M077124
- GC17M074596
- GC17M074729
- GC17M071644
- GC17M074132
- GC17M069561
Summaries for FOXJ1 Gene
-
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009]
GeneCards Summary for FOXJ1 Gene
FOXJ1 (Forkhead Box J1) is a Protein Coding gene. Diseases associated with FOXJ1 include Ciliary Dyskinesia, Primary, 43 and Primary Ciliary Dyskinesia. Among its related pathways are Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. Gene Ontology (GO) annotations related to this gene include DNA-binding transcription factor activity and DNA-binding transcription factor activity, RNA polymerase II-specific. An important paralog of this gene is FOXK2.
UniProtKB/Swiss-Prot Summary for FOXJ1 Gene
-
Transcription factor specifically required for the formation of motile cilia (PubMed:31630787). Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T). Activates the transcription of a variety of ciliary proteins in the developing brain and lung.
Additional gene information for FOXJ1 Gene
- HGNC(3816)
- Entrez Gene(2302)
- Ensembl(ENSG00000129654)
- OMIM(602291)
- UniProtKB(Q92949)
- Open Targets Platform(ENSG00000129654)
- Search for FOXJ1 at DataMed
- Search for FOXJ1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FOXJ1 Gene
Genomics for FOXJ1 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for FOXJ1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around FOXJ1 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FOXJ1
- Top Transcription factor binding sites by QIAGEN in the FOXJ1 gene promoter:
-
- FOXO1
- FOXO1a
- FOXO4
- NF-kappaB1
- Nkx5-1
- RREB-1
Genomic Locations for FOXJ1 Gene
Genomic Locations for FOXJ1 Gene
- chr17:76,136,333-76,141,245
- (GRCh38/hg38)
- Size:
- 4,913 bases
- Orientation:
- Minus strand
- chr17:74,132,414-74,137,380
- (GRCh37/hg19)
- Size:
- 4,967 bases
- Orientation:
- Minus strand
Genomic View for FOXJ1 Gene
Genes around FOXJ1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q25.1 by HGNC
- 17q25.1 by Entrez Gene
- 17q25.1 by Ensembl
FOXJ1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FOXJ1 Gene
Proteins for FOXJ1 Gene
-
Protein details for FOXJ1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q92949-FOXJ1_HUMAN
- Recommended name:
- Forkhead box protein J1
- Protein Accession:
- Q92949
- O00630
Protein attributes for FOXJ1 Gene
- Size:
- 421 amino acids
- Molecular mass:
- 45247 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for FOXJ1 Gene
Other Protein References for FOXJ1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences HFH-4 / FOXJ1 Antibody
- Novus Biologicals Antibodies for FOXJ1
-
Abcam antibodies for FOXJ1
- Invitrogen Antibodies for FOXJ1 (AFLGC-FOXJ1)
- antibodies-online: Show 13 available FOXJ1 Antibodies ranked by validation data
- Compare Top FOXJ1 Antibodies
-
Recommended
- 20 WB Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 1 IHC (p) Antibody (anti-mouse)
- 19 WB Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- 39 WB Antibodies (anti-human)
- 6 FACS Antibodies (anti-human)
- 4 IHC (p) Antibodies (anti-human)
- 2 IHC Antibodies (anti-human)
- 1 ICC Antibody (anti-human)
-
Biorbyt antibodies for FOXJ1
-
Santa Cruz Biotechnology (SCBT) Antibodies for FOXJ1
- Sino Biological Antibodies for FOXJ1
Protein Products
-
OriGene Purified Proteins for FOXJ1
- Search Origene for MassSpec and Protein Over-expression Lysates for FOXJ1
- Origene Custom Protein Services for FOXJ1
-
Abcam proteins for FOXJ1
Assay Products
- RayBiotech Custom Human FoxJ1 ELISA
- antibodies-online: Show 6 available FOXJ1 Elisa Kits ranked by validation data
- Compare Top FOXJ1 Elisa Kits
-
Quality Products:
-
Boster Bio ELISA Kits for FOXJ1
No data available for DME Specific Peptides for FOXJ1 Gene
Domains & Families for FOXJ1 Gene
Gene Families for FOXJ1 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Disease related genes
- Predicted intracellular proteins
- Transcription factors
Protein Domains for FOXJ1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FOXJ1 Gene
- GenScript: Design optimal peptide antigens:
-
- Hepatocyte nuclear factor 3 forkhead homolog 4 (FOXJ1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q92949- Family:
-
- Belongs to the FOXJ1 family.
Function for FOXJ1 Gene
Molecular function for FOXJ1 Gene
- UniProtKB/Swiss-Prot Function:
- Transcription factor specifically required for the formation of motile cilia (PubMed:31630787). Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T). Activates the transcription of a variety of ciliary proteins in the developing brain and lung.
- GENATLAS Biochemistry:
- transcription factor-like 13,with a Drosophila homeo forkhead DNA binding domain,mouse hepatocyte nuclear factor 3 homolog,expression confined to cilia/flagella producing cells
Phenotypes From GWAS Catalog for FOXJ1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000976 | transcription regulatory region sequence-specific DNA binding | IDA | 9096351 |
| GO:0000978 | RNA polymerase II proximal promoter sequence-specific DNA binding | IEA | -- |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific | ISM | 19274049 |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific | ISS | -- |
| GO:0003677 | DNA binding | NAS | 9073514 |
Phenotypes for FOXJ1 Gene
- MGI mutant phenotypes for FOXJ1:
- inferred from 6 alleles
- GenomeRNAi human phenotypes for FOXJ1:
Animal Models for FOXJ1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for FOXJ1 - Select products 50% OFF >
- * FOXJ1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for FOXJ1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FOXJ1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FOXJ1
miRNA for FOXJ1 Gene
- miRTarBase miRNAs that target FOXJ1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FOXJ1
- Browse OriGene Inhibitory RNA Products For FOXJ1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FOXJ1
Clone Products
- Applied Biological Materials (abm): Clones for FOXJ1 - Select products 50% OFF >
- * FOXJ1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for FOXJ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FOXJ1
Cell Line Products
-
Horizon Cell Lines for FOXJ1
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for FOXJ1 Gene
Localization for FOXJ1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FOXJ1 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| plasma membrane | 2 |
| extracellular | 2 |
| cytoskeleton | 2 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| endosome | 1 |
| cytosol | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000790 | nuclear chromatin | ISA | -- |
| GO:0005634 | nucleus | IEA,IDA | 17008636 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for FOXJ1 Gene
Pathways & Interactions for FOXJ1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers | ||
Pathways by source for FOXJ1 Gene
1 R&D Systems pathway for FOXJ1 Gene
Interacting Proteins for FOXJ1 Gene
Selected Interacting proteins:
Q92949-FOXJ1_HUMAN
ENSP00000323880
for FOXJ1 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for FOXJ1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000122 | negative regulation of transcription by RNA polymerase II | ISS | -- |
| GO:0002508 | central tolerance induction | ISS | -- |
| GO:0002635 | negative regulation of germinal center formation | ISS | -- |
| GO:0002897 | positive regulation of central B cell tolerance induction | ISS | -- |
| GO:0002924 | negative regulation of humoral immune response mediated by circulating immunoglobulin | ISS | -- |
No data available for SIGNOR curated interactions for FOXJ1 Gene
Transcripts for FOXJ1 Gene
mRNA/cDNA for FOXJ1 Gene
- 1 REFSEQ mRNAs :
- 4 NCBI additional mRNA sequence :
- 1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000322957 2587 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for FOXJ1 - Select products 50% OFF >
- * FOXJ1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for FOXJ1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FOXJ1
-
Santa Cruz Biotechnology (SCBT) CRISPR for FOXJ1
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FOXJ1
- Browse OriGene Inhibitory RNA Products For FOXJ1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FOXJ1
Clone Products
- Applied Biological Materials (abm): Clones for FOXJ1 - Select products 50% OFF >
- * FOXJ1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for FOXJ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FOXJ1
Relevant External Links for FOXJ1 Gene
- GeneLoc Exon Structure for
- FOXJ1
Expression for FOXJ1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Lung (Respiratory System)
- Clara Cells Respiratory Bronchioles
- Cilliated Cells Respiratory Bronchioles
- Clara Cells Trachea
- Cilliated Cells Trachea
- Non-neuroendocrine Cells Stem Bronchi
-
Brain (Nervous System)
- Myelinating Oligodendrocyte Cells Forebrain White Matter
- Mature Choroid Plexus Cells Choroid Plexus
- Choroid Plexus Progenitor Cells Choroid Plexus
- Choroid Plexus
- Midbrain tegmentum
-
Epithelial Cells
- Clara Cells Respiratory Bronchioles
- Cilliated Cells Respiratory Bronchioles
- Mature Choroid Plexus Cells Choroid Plexus
- Non-neuroendocrine Cells Stem Bronchi
- Lung epithelial-like cells(Van Haute L et. al. 2009)
- Neural Tube (Nervous System)
-
Glial Cells
- Myelinating Oligodendrocyte Cells Forebrain White Matter
- Gut Tube (Gastrointestinal Tract)
-
Testis (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for FOXJ1 Gene
This gene is overexpressed in Fallopian Tube (x9.2), Testis (x7.5), Cervix - Endocervix (x6.7), Brain - Caudate (basal ganglia) (x4.1), and Brain - Hypothalamus (x4.0).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FOXJ1
SOURCE GeneReport for Unigene cluster for FOXJ1 Gene:
Hs.651204mRNA Expression by UniProt/SwissProt for FOXJ1 Gene:
Q92949-FOXJ1_HUMAN
Tissue specificity:
Testis, oviduct, lung and brain cortex.
Evidence on tissue expression from TISSUES for FOXJ1 Gene
- Lung(4.6)
- Nervous system(4.4)
- Skin(2.3)
- Blood(2)
- Intestine(2)
Primer Products
-
OriGene qPCR primer pairs for FOXJ1
-
OriGene qPCR primer pairs and template standards for FOXJ1
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for FOXJ1 Gene
Orthologs for FOXJ1 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | FOXJ1 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | FOXJ1 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | FOXJ1 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | FOXJ1 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Foxj1 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Foxj1 30 |
|
||
| Platypus (Ornithorhynchus anatinus) |
Mammalia | FOXJ1 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | FOXJ1 30 |
|
||
| Lizard (Anolis carolinensis) |
Reptilia | FOXJ1 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | foxj1 30 |
|
||
| Str.533 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | foxJ1' 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | foxj1a 30 31 |
|
OneToOne | |
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | FKH1 31 |
|
ManyToMany | |
| FKH2 31 33 |
|
ManyToMany |
- Species where no ortholog for FOXJ1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for FOXJ1 Gene
- ENSEMBL:
- Gene Tree for FOXJ1 (if available)
- TreeFam:
- Gene Tree for FOXJ1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for FOXJ1: view image
Paralogs for FOXJ1 Gene
Paralogs for FOXJ1 Gene
- FOXK2 5
- FOXK1 5
- FOXD3 5
- FOXD1 5
- FOXA2 5
- FOXC1 5
- FOXJ3 5
- FOXI2 5
- FOXM1 5
- FOXD2 5
- FOXA1 5
- FOXC2 5
- FOXN1 5
- FOXI3 5
- FOXO1 5
- FOXL1 5
- FOXQ1 5
- FOXO4 5
- FOXL2 5
- FOXJ2 5
- FOXB1 5
- FOXE3 5
- FOXD4L1 5
- FOXO3 5
- FOXE1 5
- FOXS1 5
- ENSG00000285708 5
- FOXF1 5
- FOXA3 5
- FOXD4 5
- FOXB2 5
- FOXP1 5
- FOXL3 5
- FOXD4L6 5
- FOXD4L5 5
- FOXO6 5
- FOXH1 5
- FOXD4L4 5
- FOXD4L3 5
- FOXP3 5
- FOXR1 5
- FOXR2 5
- FOXO3B 5
Variants for FOXJ1 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FOXJ1 Gene
| SNP ID | Clinical significance and condition | Chr 17 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 800278 | Pathogenic: CILIARY DYSKINESIA, PRIMARY, 43 | 76,137,718(-) | C/A | NONSENSE | |
| 800279 | Pathogenic: CILIARY DYSKINESIA, PRIMARY, 43 | 76,137,747(-) | G/GTGCT | FRAMESHIFT_VARIANT | |
| 800280 | Pathogenic: CILIARY DYSKINESIA, PRIMARY, 43 | 76,137,793(-) | G/A | NONSENSE | |
| 800281 | Pathogenic: CILIARY DYSKINESIA, PRIMARY, 43 | 76,137,651(-) | TC/T | FRAMESHIFT_VARIANT |
Residual Variation Intolerance Score:
85.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.09;
38.21% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FOXJ1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FOXJ1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FOXJ1 Gene
Disorders for FOXJ1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| ciliary dyskinesia, primary, 43 |
|
|
| primary ciliary dyskinesia |
|
|
| obstructive hydrocephalus |
|
|
| rhinitis |
|
|
| allergic rhinitis |
|
|
Search FOXJ1 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FOXJ1_HUMAN- Allergic rhinitis (ALRH) [MIM:607154]: A common disease with complex inheritance characterized by mucosal inflammation caused by allergen exposure. {ECO:0000269 PubMed:16518568}. Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry.
- Ciliary dyskinesia, primary, 43 (CILD43) [MIM:618699]: A form of primary ciliary dyskinesia, a disorder characterized by abnormalities of motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to defects in the respiratory cilia. Patients with this disorder also develop significant obstructive hydrocephalus. Other more variable features include infertility and about a 50% chance of situs inversus or other left-right asymmetry defects. CILD43 inheritance is autosomal dominant. {ECO:0000269 PubMed:31630787}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Additional Disease Information for FOXJ1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for Genatlas for FOXJ1 Gene
Publications for FOXJ1 Gene
- Identification of single nucleotide polymorphisms in FOXJ1 and their association with allergic rhinitis. (PMID: 16518568) Li CS … Chung HT (Journal of human genetics 2006) 2 3 4 41
- The human hepatocyte nuclear factor 3/fork head gene FKHL13: genomic structure and pattern of expression. (PMID: 9073514) Murphy DB … Thies U (Genomics 1997) 2 3 4 23
- A human forkhead/winged-helix transcription factor expressed in developing pulmonary and renal epithelium. (PMID: 9530170) Pelletier GJ … Hackett BP (The American journal of physiology 1998) 3 4 23
- De Novo Mutations in FOXJ1 Result in a Motile Ciliopathy with Hydrocephalus and Randomization of Left/Right Body Asymmetry. (PMID: 31630787) Wallmeier J … Omran H (American journal of human genetics 2019) 3 4
- Association of FOXJ1 polymorphisms with systemic lupus erythematosus and rheumatoid arthritis in Korean population. (PMID: 18160851) Li CS … Chae SC (Experimental & molecular medicine 2007) 3 41
ExternalLinks
Products for FOXJ1 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FOXJ1
- Search Origene for MassSpec and Protein Over-expression Lysates for FOXJ1
- Origene Custom Protein Services for FOXJ1
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FOXJ1
- Browse OriGene Inhibitory RNA Products For FOXJ1
- OriGene qPCR primer pairs for FOXJ1
- OriGene qPCR primer pairs and template standards for FOXJ1
- OriGene CRISPR knockouts for FOXJ1
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FOXJ1
- Sino Biological Human cDNA Clone for FOXJ1
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Sino Biological Antibodies for FOXJ1
- Browse Sino Biological Assays
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for FOXJ1
- Novus Biologicals proteins and lysates for FOXJ1
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for FOXJ1
- Abcam proteins for FOXJ1
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for FOXJ1 (AFLGC-FOXJ1)
- VectorBuilder Custom and pre-made DNA vectors for FOXJ1 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for FOXJ1 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for FOXJ1 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for FOXJ1 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for FOXJ1
- antibodies-online: Show 13 available FOXJ1 Antibodies ranked by validation data
- Compare Top FOXJ1 Antibodies
- Recommended
- 20 WB Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 1 IHC (p) Antibody (anti-mouse)
- 19 WB Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- 39 WB Antibodies (anti-human)
- 6 FACS Antibodies (anti-human)
- 4 IHC (p) Antibodies (anti-human)
- 2 IHC Antibodies (anti-human)
- 1 ICC Antibody (anti-human)
- antibodies-online: Show 6 available FOXJ1 Elisa Kits ranked by validation data
- Compare Top FOXJ1 Elisa Kits
- Quality Products:
- antibodies-online: Show 6 available FOXJ1 Proteins ranked by validation data
- Compare Top FOXJ1 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for FOXJ1
- Search Santa Cruz Biotechnology (SCBT) for FOXJ1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FOXJ1
- Horizon Cell Lines for FOXJ1
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FOXJ1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FOXJ1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for FOXJ1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FOXJ1
- Biorbyt antibodies for FOXJ1
Sources for FOXJ1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB