FOXD3-AS1 Gene (RNA Gene)

FOXD3 Antisense RNA 1

GC01M063320
GIFtS:
15
See more...

Aliases for FOXD3-AS1 Gene

Data sources for FOXD3-AS1 Gene:

Subcategory (RNA class) for FOXD3-AS1 Gene

lncRNA

Aliases for FOXD3-AS1 Gene

External Ids for FOXD3-AS1 Gene

Summaries for FOXD3-AS1 Gene

GeneCards Summary for FOXD3-AS1 Gene

FOXD3-AS1 (FOXD3 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with FOXD3-AS1 include High Grade Glioma.

Additional gene information for FOXD3-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FOXD3-AS1 Gene

Genomics for FOXD3-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Download GeneHancer 2017 data
Promoters and enhancers for FOXD3-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH01J063319 Promoter/Enhancer 1.8 EPDnew FANTOM5 Ensembl ENCODE 250.7 +0.9 922 7.8 ZBTB10 FEZF1 MNT ETS1 BHLHE40 ZIC2 ZNF610 ZNF623 REST FOXA2 FOXD3 FOXD3-AS1 NONHSAG001697.2 lnc-FOXD3-4 ENSG00000236674 ALG6 HSALNG0004108 MIR6068
GH01J063522 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 12.6 -198.9 -198887 3.1 ZSCAN16 CHD2 TBP SP1 ZBTB10 MXD4 FEZF1 CEBPA SIX5 NR2C1 ITGB3BP EFCAB7 ALG6 FOXD3-AS1 FOXD3 ENSG00000235545 ROR1 DOCK7 ENSG00000236674 RF00017-234
GH01J063294 Enhancer 0.8 Ensembl ENCODE dbSUPER 12.3 +29.3 29340 2.2 ETS1 SP1 SIN3A CEBPB POU5F1 NANOG POLR2A LINC00466 FOXD3 FOXD3-AS1 ENSG00000236674 ALG6 piR-52966-001 ATG4C
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FOXD3-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for FOXD3-AS1 Gene

Latest Assembly
chr1:63,319,649-63,324,441
(GRCh38/hg38)
Size:
4,793 bases
Orientation:
Minus strand

Previous Assembly
chr1:63,786,555-63,790,112
(GRCh37/hg19 by Entrez Gene)
Size:
3,558 bases
Orientation:
Minus strand

chr1:63,786,555-63,790,112
(GRCh37/hg19 by Ensembl)
Size:
3,558 bases
Orientation:
Minus strand

Genomic View for FOXD3-AS1 Gene

Genes around FOXD3-AS1 on UCSC Golden Path with GeneCards custom track
FOXD3-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
FOXD3-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FOXD3-AS1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for FOXD3-AS1 Gene

Proteins for FOXD3-AS1 Gene

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Post-translational modifications for FOXD3-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for FOXD3-AS1 Gene

Domains & Families for FOXD3-AS1 Gene

Gene Families for FOXD3-AS1 Gene

HGNC:
genes like me logo Genes that share domains with FOXD3-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FOXD3-AS1 Gene

Function for FOXD3-AS1 Gene

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  6. Cell Lines for research

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FOXD3-AS1 Gene

Localization for FOXD3-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FOXD3-AS1 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FOXD3-AS1 Gene

Pathways & Interactions for FOXD3-AS1 Gene

PathCards logo

SuperPathways for FOXD3-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FOXD3-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for FOXD3-AS1 Gene

Drugs & Compounds for FOXD3-AS1 Gene

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No Compound Related Data Available

Transcripts for FOXD3-AS1 Gene

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Non-coding RNA (ncRNA) Transcripts from RNAcentral for FOXD3-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000056B1DC_9606 lncRNA 547 5

RefSeq: NR_121635,

Ensembl: ENST00000449386 (view in UCSC) ,

LNCipedia: FOXD3-AS1:6,

NONCODE: NONHSAT003668.2,

ENA: KF925351.1:1..547:ncRNA,

URS00000199FC_9606 lncRNA 472 5

Ensembl: ENST00000426393 (view in UCSC) ,

LncBook: HSALNT0008160,

LNCipedia: FOXD3-AS1:12,

NONCODE: NONHSAT003669.2,

ENA: KF925354.1:1..470:ncRNA,

URS000036F04B_9606 lncRNA 945 4

Ensembl: ENST00000418244 (view in UCSC) ,

LncBook: HSALNT0008168,

LNCipedia: FOXD3-AS1:8,

ENA: KF925352.1:1..941:ncRNA, KJ493778.1:1..941:ncRNA,

URS00001ECD7E_9606 lncRNA 499 4

Ensembl: ENST00000431294 (view in UCSC) ,

LncBook: HSALNT0008166,

LNCipedia: FOXD3-AS1:4,

ENA: KF925350.1:1..496:ncRNA,

URS00001F96A0_9606 lncRNA 494 4

RefSeq: NR_121637,

Ensembl: ENST00000427268 (view in UCSC) ,

LNCipedia: FOXD3-AS1:1,

ENA: KF925349.1:1..491:ncRNA,

FOXD3-AS1 in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for FOXD3-AS1 Gene

7 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for FOXD3-AS1 Gene

No ASD Table

Relevant External Links for FOXD3-AS1 Gene

GeneLoc Exon Structure for
FOXD3-AS1

Expression for FOXD3-AS1 Gene

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mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FOXD3-AS1 Gene

mRNA expression in normal human tissues for FOXD3-AS1 Gene
mRNA expression by GTEx for FOXD3-AS1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FOXD3-AS1

genes like me logo Genes that share expression patterns with FOXD3-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FOXD3-AS1 Gene

Orthologs for FOXD3-AS1 Gene

Evolution for FOXD3-AS1 Gene

ENSEMBL:
Gene Tree for FOXD3-AS1 (if available)
TreeFam:
Gene Tree for FOXD3-AS1 (if available)

No data available for Orthologs for FOXD3-AS1 Gene

Paralogs for FOXD3-AS1 Gene

No data available for Paralogs for FOXD3-AS1 Gene

Variants for FOXD3-AS1 Gene

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  1. SNP Genotyping and Copy Number Assays for research

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FOXD3-AS1 Gene

SNP ID Clinical significance and condition Chr 01 pos Variation AA Info Type
rs114453593 Benign: not provided 63,323,697(-) C/T
NM_012183.3(FOXD3):c.639C>T (p.Asn213=) 		SYNONYMOUS

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for FOXD3-AS1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for FOXD3-AS1 Gene

Variant ID Type Subtype PubMed ID
nsv461672 CNV gain 19166990
nsv470714 CNV gain 18288195
nsv546433 CNV gain 21841781

Additional Variant Information for FOXD3-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FOXD3-AS1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FOXD3-AS1 Gene

Disorders for FOXD3-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for FOXD3-AS1 Gene - From: LNC and COP

Disorder Aliases PubMed IDs
high grade glioma
  • glial cell tumor
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for FOXD3-AS1

Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with FOXD3-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FOXD3-AS1 Gene

Publications for FOXD3-AS1 Gene

  1. Down-regulation of long non-coding RNA FOXD3 antisense RNA 1 (FOXD3-AS1) inhibits cell proliferation, migration, and invasion in malignant glioma cells. (PMID: 27829996) Chen ZH … Jiang L (American journal of translational research 2016) 2 3 74
  2. Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150. (PMID: 28655711) Zhang D … Jin Y (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017) 2 3
  3. Inhibition of LncRNA FOXD3-AS1 suppresses the aggressive biological behaviors of thyroid cancer via elevating miR-296-5p and inactivating TGF-β1/Smads signaling pathway. (PMID: 31678422) Chen Y … Li Y (Molecular and cellular endocrinology 2020) 3
  4. LncRNA FOXD3-AS1 promotes proliferation, invasion and migration of cutaneous malignant melanoma via regulating miR-325/MAP3K2. (PMID: 31541886) Chen X … Pan Y (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019) 3
  5. Long noncoding RNA FOXD3-AS1 promotes colon adenocarcinoma progression and functions as a competing endogenous RNA to regulate SIRT1 by sponging miR-135a-5p. (PMID: 31058315) Wu Q … Ma J (Journal of cellular physiology 2019) 3

ExternalLinks

View latest publications for FOXD3-AS1 gene in Mastermind

Products for FOXD3-AS1 Gene

Sources for FOXD3-AS1 Gene