Aliases for FNDC4 Gene
Fibronectin Type III Domain Containing 4
Fibronectin Type III Domain-Containing Protein 4 3
Fibronectin Type III Repeat-Containing Protein 1 3
External Ids for FNDC4 Gene
Previous GeneCards Identifiers for FNDC4 Gene
FNDC4 (Fibronectin Type III Domain Containing 4) is a Protein Coding gene.
Diseases associated with FNDC4 include Fuchs' Endothelial Dystrophy.
An important paralog of this gene is FNDC5.
Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
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Entrez Gene Summary ,
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for FNDC4 Gene