Aliases for FMR1-AS1 Gene

Subcategory (RNA class) for FMR1-AS1 Gene

lncRNA

Number of RNA Genes sources:

3 / 17

Aliases for FMR1-AS1 Gene

  • FMR1 Antisense RNA 1 2 3 5
  • FMR1-AS1 2 5 165
  • FMR1 Antisense RNA 1 (Non-Protein Coding) 2 3
  • FMR1 Antisense RNA 1 (Head To Head) 2 3
  • ASFMR1 2 3
  • FMR4 2 3
  • Antisense Fragile X Mental Retardation Protein Variant A 3
  • Antisense Fragile X Mental Retardation Protein 2
  • FMR1 Antisense RNA (Non-Protein Coding) 2
  • NONHSAG055480.2 91
  • HSALNG0140560 164
  • FMR1-AS 3
  • FMR1AS 3

External Ids for FMR1-AS1 Gene

Previous HGNC Symbols for FMR1-AS1 Gene

  • FMR1AS
  • FMR1-AS

Previous GeneCards Identifiers for FMR1-AS1 Gene

  • GC0XM146993

Summaries for FMR1-AS1 Gene

GeneCards Summary for FMR1-AS1 Gene

FMR1-AS1 (FMR1 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with FMR1-AS1 include Fragile X Tremor/Ataxia Syndrome and Cerebellar Atrophy, Developmental Delay, And Seizures.

Gene Wiki entry for FMR1-AS1 Gene

Rfam classification for FMR1-AS1 Gene

  • FMR1 antisense RNA 1 conserved region 2
  • FMR1 antisense RNA 1 conserved region 1

Additional gene information for FMR1-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary and piRNA Summary for FMR1-AS1 Gene

Genomics for FMR1-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for FMR1-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ147908 Promoter/Enhancer 2 EPDnew Ensembl ENCODE CraniofacialAtlas 0.4 +9.6 9563 7.7 CREB1 PRDM10 TFE3 ZNF512 ZNF692 TARDBP FOXA1 PRDM1 ZIC2 RBFOX2 ENSG00000274086 FMR1 KC894604 FMR1-AS1 FMR1NB
GH0XJ147917 Enhancer 0.6 ENCODE 0.7 +4.1 4116 2 GABPA PKNOX1 ZBTB40 ELF1 JUNB ZNF384 BATF GABPB1 ETV6 CREM ENSG00000227083 FMR1-AS1 FMR1 FMR1NB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FMR1-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for FMR1-AS1 Gene

Genomic Locations for FMR1-AS1 Gene
chrX:147,904,604-147,922,158
(GRCh38/hg38)
Size:
17,555 bases
Orientation:
Minus strand
chrX:146,990,949-147,003,676
(GRCh37/hg19)
Size:
12,728 bases
Orientation:
Minus strand

Genomic View for FMR1-AS1 Gene

Genes around FMR1-AS1 on UCSC Golden Path with GeneCards custom track
FMR1-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
FMR1-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FMR1-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FMR1-AS1 Gene

Proteins for FMR1-AS1 Gene

Post-translational modifications for FMR1-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for FMR1-AS1 Gene

Domains & Families for FMR1-AS1 Gene

Gene Families for FMR1-AS1 Gene

Suggested Antigen Peptide Sequences for FMR1-AS1 Gene

GenScript: Design optimal peptide antigens:
  • Antisense fragile X mental retardation protein variant E (A8TMB7_HUMAN)
genes like me logo Genes that share domains with FMR1-AS1: view

No data available for Protein Domains , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FMR1-AS1 Gene

Function for FMR1-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FMR1-AS1 Gene

Localization for FMR1-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FMR1-AS1 gene
Compartment Confidence
plasma membrane 1
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FMR1-AS1 Gene

Pathways & Interactions for FMR1-AS1 Gene

PathCards logo

SuperPathways for FMR1-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for FMR1-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0043066 negative regulation of apoptotic process IEA --
genes like me logo Genes that share ontologies with FMR1-AS1: view

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for FMR1-AS1 Gene

Drugs & Compounds for FMR1-AS1 Gene

No Compound Related Data Available

Transcripts for FMR1-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for FMR1-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS00008121A2_9606 lncRNA 2387 3

HGNC: 39081,

RefSeq: NR_024499,

LNCipedia: FMR1-AS1:8,

URS0000812191_9606 lncRNA 2005 3

RefSeq: NR_024501,

Ensembl: ENST00000594922 (view in UCSC) ,

LNCipedia: FMR1-AS1:9,

URS000081217E_9606 lncRNA 1845 3

RefSeq: NR_024502,

Ensembl: ENST00000596112 (view in UCSC) ,

LNCipedia: FMR1-AS1:10,

URS000081210B_9606 lncRNA 1741 3

RefSeq: NR_024503,

Ensembl: ENST00000598667 (view in UCSC) ,

LNCipedia: FMR1-AS1:7,

URS000075A3E9_9606 lncRNA 3026 2

LNCipedia: FMR1-AS1:5,

NONCODE: NONHSAT138910.2,

FMR1-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for FMR1-AS1 Gene

10 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for FMR1-AS1 Gene

No ASD Table

Relevant External Links for FMR1-AS1 Gene

GeneLoc Exon Structure for
FMR1-AS1

Expression for FMR1-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for FMR1-AS1 Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FMR1-AS1

SOURCE GeneReport for Unigene cluster for FMR1-AS1 Gene:

Hs.561999
genes like me logo Genes that share expression patterns with FMR1-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FMR1-AS1 Gene

Orthologs for FMR1-AS1 Gene

Evolution for FMR1-AS1 Gene

ENSEMBL:
Gene Tree for FMR1-AS1 (if available)
TreeFam:
Gene Tree for FMR1-AS1 (if available)

No data available for Orthologs for FMR1-AS1 Gene

Paralogs for FMR1-AS1 Gene

No data available for Paralogs for FMR1-AS1 Gene

Variants for FMR1-AS1 Gene

Additional dbSNP identifiers (rs#s) for FMR1-AS1 Gene

Structural Variations from Database of Genomic Variants (DGV) for FMR1-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv2506e212 CNV loss 25503493
esv3574912 CNV loss 25503493
nsv7141 CNV deletion 18451855

Additional Variant Information for FMR1-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FMR1-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP and Variation tolerance for FMR1-AS1 Gene

Disorders for FMR1-AS1 Gene

MalaCards: The human disease database

(8) MalaCards diseases for FMR1-AS1 Gene - From: LncRNADisease, DISEASES, and GeneCards

- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for FMR1-AS1

genes like me logo Genes that share disorders with FMR1-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FMR1-AS1 Gene

Publications for FMR1-AS1 Gene

  1. A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. (PMID: 18213394) Khalil AM … Wahlestedt C (PloS one 2008) 2 3
  2. An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals. (PMID: 17921506) Ladd PD … Filippova GN (Human molecular genetics 2007) 2 3
  3. Exosomal FMR1-AS1 facilitates maintaining cancer stem-like cell dynamic equilibrium via TLR7/NFκB/c-Myc signaling in female esophageal carcinoma. (PMID: 30736860) Li W … Zhou Y (Molecular cancer 2019) 3
  4. The long non-coding RNA FMR4 promotes proliferation of human neural precursor cells and epigenetic regulation of gene expression in trans. (PMID: 27001315) Peschansky VJ … Wahlestedt C (Molecular and cellular neurosciences 2016) 3
  5. Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome. (PMID: 24005575) Pastori C … Wahlestedt C (Human genetics 2014) 3

Products for FMR1-AS1 Gene

Sources for FMR1-AS1 Gene