Aliases for FMNL1 Gene
External Ids for FMNL1 Gene
Previous HGNC Symbols for FMNL1 Gene
Previous GeneCards Identifiers for FMNL1 Gene
This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for FMNL1 Gene
FMNL1 (Formin Like 1) is a Protein Coding gene. Diseases associated with FMNL1 include Malignant Breast Melanoma and Cerebral Amyloid Angiopathy, Itm2b-Related, 2. Among its related pathways are Signaling by GPCR and Signaling by Rho GTPases. Gene Ontology (GO) annotations related to this gene include binding and actin filament binding. An important paralog of this gene is FMNL2.
UniProtKB/Swiss-Prot Summary for FMNL1 Gene
May play a role in the control of cell motility and survival of macrophages (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape.