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This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015] See more...
Aliases for FMN1 Gene
Aliases for FMN1 Gene
External Ids for FMN1 Gene
- HGNC: 3768
- Entrez Gene: 342184
- Ensembl: ENSG00000248905
- OMIM: 136535
- UniProtKB: Q68DA7
Previous HGNC Symbols for FMN1 Gene
- LD
- FMN
Previous GeneCards Identifiers for FMN1 Gene
- GC15M030854
- GC15M033066
- GC15M009919
- GC15M033059
Summaries for FMN1 Gene
-
This gene belongs to the formin homology family and encodes a protein that has a role in the formation of adherens junction and the polymerization of linear actin cables. The homologous gene in mouse is associated with limb deformity. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]
GeneCards Summary for FMN1 Gene
FMN1 (Formin 1) is a Protein Coding gene. Diseases associated with FMN1 include Renal Hypoplasia and Thoracic Outlet Syndrome. Among its related pathways are E-cadherin signaling in keratinocytes and Cell adhesion_Cadherin-mediated cell adhesion. Gene Ontology (GO) annotations related to this gene include actin binding and microtubule binding.
UniProtKB/Swiss-Prot Summary for FMN1 Gene
-
Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
Additional gene information for FMN1 Gene
- Monarch Initiative
- Search for FMN1 at DataMed
- Search for FMN1 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FMN1 Gene
Genomics for FMN1 Gene
GeneHancer (GH) Regulatory Elements for FMN1 Gene
Promoters and enhancers for FMN1 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH15J033194 | Promoter/Enhancer | 1.7 | EPDnew Ensembl ENCODE CraniofacialAtlas | 759.4 | -0.2 | -216 | 1.6 | SP1 FOS L3MBTL2 MNT ZNF148 IKZF1 GLIS2 CREB1 PKNOX1 PRDM10 | FMN1 LOC105370759 lnc-RYR3-1 | |
| GH15J033066 | Promoter/Enhancer | 1.6 | EPDnew Ensembl ENCODE CraniofacialAtlas | 768.9 | +127.0 | 127049 | 5.9 | TCF7L2 ZNF217 MNT ELF3 NCOA3 MAFK SP7 CEBPG KAT8 CREB1 | FMN1 lnc-GOLGA8O-9 ENSG00000212415 piR-53063-072 | |
| GH15J033209 | Promoter/Enhancer | 1.1 | EPDnew FANTOM5 Ensembl ENCODE | 755.7 | -15.6 | -15617 | 1.2 | POLR2A ZBTB17 | FMN1 RF00017-1743 FJ601684-125 LOC105370759 | |
| GH15J033170 | Promoter | 0.3 | EPDnew | 750.3 | +24.2 | 24181 | 0.1 | FMN1 HSALNG0104897 | ||
| GH15J033021 | Enhancer | 1 | Ensembl ENCODE CraniofacialAtlas dbSUPER | 25.8 | +171.8 | 171760 | 2.4 | CTCF RAD21 PRDM10 SCRT2 SCRT1 SMC3 ATF2 | FMN1 ENSG00000212415 ENSG00000241818 SCG5 piR-53063-072 lnc-GOLGA8O-9 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around FMN1 on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the FMN1 gene promoter:
-
- AP-1
- c-Jun
- STAT3
- TBP
- TFIID
Genomic Locations for FMN1 Gene
Genomic Locations for FMN1 Gene
- chr15:32,765,544-33,194,784
- (GRCh38/hg38)
- Size:
- 429,241 bases
- Orientation:
- Minus strand
- chr15:33,057,747-33,486,897
- (GRCh37/hg19)
- Size:
- 429,151 bases
- Orientation:
- Minus strand
Genomic View for FMN1 Gene
Genes around FMN1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q13.3 by HGNC
- 15q13.3 by Entrez Gene
- 15q13.3 by Ensembl
FMN1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FMN1 Gene
Proteins for FMN1 Gene
-
Protein details for FMN1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q68DA7-FMN1_HUMAN
- Recommended name:
- Formin-1
- Protein Accession:
- Q68DA7
- Q3B7I6
- Q3ZAR4
- Q6ZSY1
Protein attributes for FMN1 Gene
- Size:
- 1419 amino acids
- Molecular mass:
- 157578 Da
- Quaternary structure:
-
- Interacts with alpha-catenin and may interact with tubulin.
Protein Expression for FMN1 Gene
Post-translational modifications for FMN1 Gene
- Phosphorylated on serine and possibly threonine residues.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for FMN1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- NSJ Bioreagents Formin Antibody / FMN1
- Atlas Antibodies Anti-FMN1 Antibody (HPA005465) and Anti-FMN1 Antibody (HPA046786)
- Creative Diagnostics Anti-FMN1 monoclonal antibody, Anti-FMN1 monoclonal antibody, clone 5G5, and Anti-FMN1 (full length) polyclonal antibody
- Creative Biolabs Mouse Anti-FMN1 Recombinant Antibody (4F4)
-
Custom Antibody ServicesOriGene Antibodies for FMN1
- Novus Biologicals Antibodies for FMN1
-
Abcam antibodies for FMN1
- Invitrogen Antibodies for FMN1 (AFLGC-FMN1)
-
Biorbyt antibodies for FMN1
-
Boster Bio Antibodies for FMN1
-
Santa Cruz Biotechnology (SCBT) Antibodies for FMN1
Protein Products
- Atlas Antibodies PrEST Antigen FMN1 (APrEST70054) and PrEST Antigen FMN1 (APrEST70053)
- Creative Biomart Recombinant Human FMN1 cell lysate
-
OriGene Purified Proteins for FMN1
- Search Origene for MassSpec and Protein Over-expression Lysates for FMN1
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-
Abcam proteins for FMN1
Assay Products
- antibodies-online: Show 6 available FMN1 Elisa Kits ranked by validation data
- Compare Top FMN1 Elisa Kits
-
Quality Products:
No data available for DME Specific Peptides for FMN1 Gene
Domains & Families for FMN1 Gene
Gene Families for FMN1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for FMN1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FMN1 Gene
- GenScript: Design optimal peptide antigens:
-
- Limb deformity protein homolog (FMN1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q68DA7- Family:
-
- Belongs to the formin homology family. Cappuccino subfamily.
Function for FMN1 Gene
Molecular function for FMN1 Gene
- UniProtKB/Swiss-Prot Function:
- Plays a role in the formation of adherens junction and the polymerization of linear actin cables.
Phenotypes From GWAS Catalog for FMN1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003779 | actin binding | IBA | 21873635 |
| GO:0008017 | microtubule binding | IBA | 21873635 |
| GO:0017124 | SH3 domain binding | IEA | -- |
Phenotypes for FMN1 Gene
- MGI mutant phenotypes for FMN1:
- inferred from 12 alleles
- GenomeRNAi human phenotypes for FMN1:
-
- Decreased focal adhesion (FA) area, decreased FA length, decreased FA mean intensity, increased number of small and round FAs, increased FA abundance
- Decreased ionizing radiation sensitivity
- Increased cell migration
- Decreased cell migration
- Increased vaccinia virus (VACV) infection
- Synthetic lethal with Ras
- Increased Sindbis virus (SINV) infection
- Lamellipodia cells
Animal Models for FMN1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
-
OriGene CRISPR knockouts for FMN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FMN1
- genomics-online: gRNA clones - Search for available FMN1 gRNA products
- Overview of 97 available FMN1 gene related products
- Applied Biological Materials (abm): CRISPR Clones for FMN1 - Select products 50% OFF >
- * FMN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * FMN1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for FMN1
miRNA for FMN1 Gene
- miRTarBase miRNAs that target FMN1
-
- hsa-mir-136-3p (MIRT440635)
- hsa-mir-493-3p (MIRT440636)
- hsa-mir-432-5p (MIRT440637)
- hsa-mir-340-5p (MIRT563811)
- hsa-mir-219b-3p (MIRT563812)
- hsa-mir-92b-3p (MIRT563813)
- hsa-mir-92a-3p (MIRT563814)
- hsa-mir-367-3p (MIRT563815)
- hsa-mir-363-3p (MIRT563816)
- hsa-mir-25-3p (MIRT563817)
- hsa-mir-32-5p (MIRT563818)
- hsa-mir-6504-3p (MIRT563819)
- hsa-mir-513c-3p (MIRT563820)
- hsa-mir-513a-3p (MIRT563821)
- hsa-mir-3606-3p (MIRT563822)
- hsa-mir-5698 (MIRT636511)
- hsa-mir-143-5p (MIRT636512)
- hsa-mir-3907 (MIRT636513)
- hsa-mir-4430 (MIRT636514)
- hsa-mir-3652 (MIRT636515)
- hsa-mir-122-5p (MIRT636516)
- hsa-mir-504-3p (MIRT636517)
- hsa-mir-3135b (MIRT636518)
- hsa-mir-6499-3p (MIRT636519)
- hsa-mir-4638-5p (MIRT636520)
- hsa-mir-1307-3p (MIRT636521)
- hsa-mir-6833-3p (MIRT658130)
- hsa-mir-4768-5p (MIRT658131)
- hsa-mir-6873-3p (MIRT658132)
- hsa-mir-6515-3p (MIRT658133)
- hsa-mir-1236-3p (MIRT658134)
- hsa-mir-6777-3p (MIRT658135)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for FMN1
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- Overview of 97 available FMN1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for FMN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FMN1
- genomics-online: cdna clones - Search for available FMN1 CDNA products
- Overview of 97 available FMN1 gene related products
- orf clones - Search for available FMN1 ORF products
- Overview of 97 available FMN1 gene related products
- Applied Biological Materials (abm): Clones for FMN1 - Select products 50% OFF >
- * FMN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * FMN1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Cell Line Products
-
Horizon Cell Lines for FMN1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FMN1 Gene
Localization for FMN1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FMN1 Gene
- Nucleus. Cytoplasm. Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Localization to the adherens junctions is alpha-catenin-dependent. Also localizes to F-actin bundles originating from adherens junctions and to microtubules (By similarity). {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 4 |
| cytoskeleton | 4 |
| nucleus | 3 |
| endoplasmic reticulum | 3 |
| endosome | 1 |
| golgi apparatus | 1 |
- Cytosol (3)
- Nucleoplasm (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IBA | 21873635 |
| GO:0005737 | cytoplasm | IBA | 21873635 |
| GO:0005789 | endoplasmic reticulum membrane | IBA | 21873635 |
| GO:0005884 | actin filament | IEA | -- |
| GO:0005886 | plasma membrane | IEA | -- |
Pathways & Interactions for FMN1 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cell adhesion_Cadherin-mediated cell adhesion | ||
| 2 | E-cadherin signaling in keratinocytes | ||
Pathways by source for FMN1 Gene
1 BioSystems pathway for FMN1 Gene
1 GeneGo (Thomson Reuters) pathway for FMN1 Gene
Interacting Proteins for FMN1 Gene
GPS-Prot Interaction Network for FMN1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0010467 | gene expression | IEA | -- |
| GO:0030838 | positive regulation of actin filament polymerization | IEA | -- |
| GO:0035136 | forelimb morphogenesis | IEA | -- |
| GO:0035137 | hindlimb morphogenesis | IEA | -- |
| GO:0045010 | actin nucleation | IEA | -- |
No data available for SIGNOR curated interactions for FMN1 Gene
Drugs & Compounds for FMN1 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
- Atlas Antibodies PrEST Antigen FMN1 (APrEST70054) and PrEST Antigen FMN1 (APrEST70053)
- Creative Biomart Recombinant Human FMN1 cell lysate
Transcripts for FMN1 Gene
mRNA/cDNA for FMN1 Gene
- (4) REFSEQ mRNAs :
- (11) Additional mRNA sequences :
- (88) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000334528 12355 bps (ENST00000334528.13)
- ENST00000561249 4251 bps (ENST00000561249.5)
- ENST00000559047 4260 bps (ENST00000559047.5)
- ENST00000558882 570 bps (ENST00000558882.1)
- ENST00000559610 393 bps (ENST00000559610.1)
CRISPR Products
-
OriGene CRISPR knockouts for FMN1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FMN1
- genomics-online: gRNA clones - Search for available FMN1 gRNA products
- Overview of 97 available FMN1 gene related products
- Applied Biological Materials (abm): CRISPR Clones for FMN1 - Select products 50% OFF >
- * FMN1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * FMN1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
Santa Cruz Biotechnology (SCBT) CRISPR for FMN1
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for FMN1
- Browse OriGene Inhibitory RNA Products For FMN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FMN1
- genomics-online: shRNA clones - Search for available FMN1 shRNA products
- Overview of 97 available FMN1 gene related products
Clone Products
- Sino Biological Human cDNA Clone for FMN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FMN1
- genomics-online: cdna clones - Search for available FMN1 CDNA products
- Overview of 97 available FMN1 gene related products
- orf clones - Search for available FMN1 ORF products
- Overview of 97 available FMN1 gene related products
- Applied Biological Materials (abm): Clones for FMN1 - Select products 50% OFF >
- * FMN1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * FMN1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
Expression for FMN1 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Eye (Sensory Organs)
- Type1 Off Cone Bipolar Cells Inner Nuclear Layer
-
Neurons
- Type1 Off Cone Bipolar Cells Inner Nuclear Layer
This gene is overexpressed in Retina (49.7) and Peripheral blood mononuclear cells (8.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FMN1 Gene
NURSA nuclear receptor signaling pathways regulating expression of FMN1 Gene:
FMN1SOURCE GeneReport for Unigene cluster for FMN1 Gene:
Hs.657649Evidence on tissue expression from TISSUES for FMN1 Gene
- Nervous system(4.4)
- Eye(4.1)
- Liver(4.1)
- Skin(2.8)
Primer Products
-
OriGene qPCR primer pairs for FMN1
- genomics-online: primer clones - Search for available FMN1 Primer products
- Overview of 97 available FMN1 gene related products
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FMN1 Gene
Orthologs for FMN1 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FMN1 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | -- 33 |
|
OneToMany | |
| -- 33 |
|
OneToMany | |||
| mouse (Mus musculus) |
Mammalia | Fmn1 17 33 32 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FMN1 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Fmn1 32 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | FMN1 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | FMN1 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | FMN1 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | fmn1 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | FMN1 (4 of 4) 33 |
|
OneToMany | |
| FMN1 (2 of 4) 33 |
|
OneToMany | |||
| FMN1 (3 of 4) 33 |
|
OneToMany | |||
| fmn1 33 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | capu 33 |
|
OneToMany |
- Species where no ortholog for FMN1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for FMN1 Gene
- ENSEMBL:
- Gene Tree for FMN1 (if available)
- TreeFam:
- Gene Tree for FMN1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for FMN1: view image
Paralogs for FMN1 Gene
(2) SIMAP similar genes for FMN1 Gene using alignment to 6 proteins:
- FMN1_HUMAN
- H0YL93_HUMAN
- H0YLM7_HUMAN
- H0YM30_HUMAN
- H0YMP0_HUMAN
- L8EC76_HUMAN
Pseudogenes.org Pseudogenes for FMN1 Gene
No data available for Paralogs for FMN1 Gene
Variants for FMN1 Gene
| SNP ID | Clin | Chr 15 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs111822533 | likely-benign, not specified | 33,067,775(-) | G/C/T | coding_sequence_variant, genic_downstream_transcript_variant, intron_variant, missense_variant | |
| rs114851360 | likely-benign, not specified | 32,774,309(-) | C/T | 3_prime_UTR_variant, genic_downstream_transcript_variant | |
| rs139446870 | likely-benign, not specified | 32,910,491(-) | C/T | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant | |
| rs144234543 | likely-benign, not specified | 32,969,387(-) | C/A/T | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant, stop_gained | |
| rs199592529 | likely-benign, not specified | 32,964,244(-) | G/A | coding_sequence_variant, genic_downstream_transcript_variant, missense_variant |
Residual Variation Intolerance Score:
87.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
17.56;
98.25% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FMN1 Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FMN1 Gene
Disorders for FMN1 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| renal hypoplasia |
|
|
| thoracic outlet syndrome |
|
|
| auditory neuropathy, autosomal dominant, 1 |
|
|
| sarcomatosis |
|
|
| cerebral amyloid angiopathy, itm2b-related, 2 |
|
|
Search FMN1 in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for FMN1
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for FMN1 Gene
Publications for FMN1 Gene
- A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs. (PMID: 1673046) Maas RL … Leder P (American journal of human genetics 1991) 2 3 4 23 56
- Identification and characterization of the human FMN1 gene in silico. (PMID: 15202026) Katoh M … Katoh M (International journal of molecular medicine 2004) 3 4 23 56
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 43 56
- Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. (PMID: 20023658) Mangold E … Nöthen MM (Nature genetics 2010) 3 43 56
- [A study of the single nucleotide polymorphism in seven genes (GHR, IGFBP3, IGFR1, IRS1, FMN1, ANXA2, TaGLN) in ethnic Russians and in patients with prostate cancer]. (PMID: 20540360) Lisitskaia KV … Shishkin SS (Molekuliarnaia genetika, mikrobiologiia i virusologiia 2010) 3 43 56
ExternalLinks
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- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Invitrogen Antibodies for FMN1 (AFLGC-FMN1)
- antibodies-online: Show 3 available FMN1 Antibodies ranked by validation data
- Compare Top FMN1 Antibodies
- antibodies-online: Show 6 available FMN1 Elisa Kits ranked by validation data
- Compare Top FMN1 Elisa Kits
- Quality Products:
- antibodies-online: Show 4 available FMN1 Proteins ranked by validation data
- Compare Top FMN1 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for FMN1
- Search Santa Cruz Biotechnology (SCBT) for FMN1 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FMN1
- Horizon Cell Lines for FMN1
- genomics-online: cdna clones - Search for available FMN1 CDNA products
- Overview of 97 available FMN1 gene related products
- orf clones - Search for available FMN1 ORF products
- Overview of 97 available FMN1 gene related products
- genomics-online: gRNA clones - Search for available FMN1 gRNA products
- Overview of 97 available FMN1 gene related products
- genomics-online: primer clones - Search for available FMN1 Primer products
- Overview of 97 available FMN1 gene related products
- genomics-online: shRNA clones - Search for available FMN1 shRNA products
- Overview of 97 available FMN1 gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FMN1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FMN1
- Search GeneCopoeia for miRNA 3'UTR Target clone products for FMN1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FMN1
- Boster Bio Antibodies for FMN1
- Browse Boster Bio ELISA Kits
- Biorbyt antibodies for FMN1
Sources for FMN1 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
- (83) MaxQB
- (84) IUPHAR
- (85) BioGPS
- (86) Illumina
- (87) COMPARTMENTS
- (88) HOMER
- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
- (94) NONCODE
- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
- (102) SCBT
- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
- (108) NIH Rare Diseases
- (109) Orphanet
- (110) UMLS
- (111) GTR
- (112) Disease Ontology
- (113) Genetics Home Reference
- (114) MeSH
- (115) MedlinePlus
- (116) CDC
- (117) NINDS
- (118) NCBI Bookshelf
- (119) ClinVar
- (120) Gene Damage Index
- (121) HPO
- (122) UDN
- (123) VISTA
- (124) FANTOM5
- (125) ENCODE
- (126) ProSci
- (127) Horizon
- (128) NURSA
- (129) IID
- (130) VectorBuilder
- (131) SNPedia
- (132) BRCA Exchange
- (133) CIViC
- (134) ProteoGenix
- (135) dbSUPER
- (136) TISSUES
- (137) Gene ORGANizer
- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
- (145) UCNEbase
- (146) EPDnew
- (147) Applied Biosystems
- (148) GlyConnect
- (149) Aminode
- (150) GeneCopoeia
- (151) GPS-Prot
- (152) RNACentral
- (153) LncRNADisease
- (154) LOVD
- (155) miR2Disease
- (156) DiseaseEnhancer
- (157) Boster Bio
- (158) Biorbyt
- (159) Biocompare
- (160) Mastermind
- (161) CTD^2 Dashboard
- (162) CraniofacialAtlas
- (163) GeneImprint
- (164) Synthego
- (165) Bio Basic
- (166) ENA
- (167) GtRNAdb
- (168) LncBase
- (169) LncBook
- (170) LNCipedia
- (171) LncRNAdb
- (172) Modomics
- (173) PDBe
- (174) Rfam
- (175) SILVA
- (176) snOPY
- (177) SRPDB
- (178) GENCODE
- (179) TarBase
- (180) MyBioSource