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Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawal... See more...
Aliases for FLT3LG Gene
Aliases for FLT3LG Gene
External Ids for FLT3LG Gene
- HGNC: 3766
- Entrez Gene: 2323
- Ensembl: ENSG00000090554
- OMIM: 600007
- UniProtKB: P49771
Previous GeneCards Identifiers for FLT3LG Gene
- GC19P050635
- GC19P050345
- GC19P054653
- GC19P054669
- GC19P049977
- GC19P046355
Summaries for FLT3LG Gene
-
Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).[supplied by OMIM, Jan 2011]
GeneCards Summary for FLT3LG Gene
FLT3LG (Fms Related Receptor Tyrosine Kinase 3 Ligand) is a Protein Coding gene. Diseases associated with FLT3LG include Aplastic Anemia and Severe Combined Immunodeficiency. Among its related pathways are Hematopoietic cell lineage and Ras signaling pathway. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and cytokine activity.
UniProtKB/Swiss-Prot Summary for FLT3LG Gene
-
Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
Additional gene information for FLT3LG Gene
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FLT3LG Gene
Genomics for FLT3LG Gene
GeneHancer (GH) Regulatory Elements for FLT3LG Gene
Promoters and enhancers for FLT3LG Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around FLT3LG on UCSC Golden Path with GeneCards custom track
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FLT3LG
- Top Transcription factor binding sites by QIAGEN in the FLT3LG gene promoter:
-
- AP-2alpha
- AP-2alphaA
- AP-2beta
- AP-2gamma
- AP-4
- c-Ets-1
- NF-kappaB
- NF-kappaB1
- RelA
- TBP
Genomic Locations for FLT3LG Gene
Genomic Locations for FLT3LG Gene
- chr19:49,474,172-49,486,234
- (GRCh38/hg38)
- Size:
- 12,063 bases
- Orientation:
- Plus strand
- chr19:49,977,464-49,989,488
- (GRCh37/hg19)
- Size:
- 12,025 bases
- Orientation:
- Plus strand
Genomic View for FLT3LG Gene
Genes around FLT3LG on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.33 by HGNC
- 19q13.33 by Entrez Gene
- 19q13.33 by Ensembl
FLT3LG Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FLT3LG Gene
Proteins for FLT3LG Gene
-
Protein details for FLT3LG Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P49771-FLT3L_HUMAN
- Recommended name:
- Fms-related tyrosine kinase 3 ligand
- Protein Accession:
- P49771
- A0AVC2
- B9EGH2
- Q05C96
Protein attributes for FLT3LG Gene
- Size:
- 235 amino acids
- Molecular mass:
- 26416 Da
- Quaternary structure:
-
- Homodimer (isoform 2).
Post-translational modifications for FLT3LG Gene
Other Protein References for FLT3LG Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- G Biosciences Immunotag™ FLT3LG Antibody
- Creative Diagnostics Anti-FLT3L monoclonal antibody, clone 50527
- Creative Biolabs Recombinant Anti-Human FLT3LG Antibody
-
Custom Antibody ServicesOriGene Antibodies for FLT3LG
- Novus Biologicals Antibodies for FLT3LG
-
Abcam antibodies for FLT3LG
- Invitrogen Antibodies for FLT3LG (AFLGC-FLT3LG)
-
Biorbyt antibodies for FLT3LG
-
Custom Antibody ServicesProSci Antibodies for FLT3LG
-
Santa Cruz Biotechnology (SCBT) Antibodies for FLT3LG
- Sino Biological Antibodies for FLT3LG
Protein Products
- Creative Biomart Recombinant Human Fms-related Tyrosine Kinase 3 Ligand
- Search Origene for MassSpec and Protein Over-expression Lysates for FLT3LG
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- Sino Biological Recombinant Proteins for FLT3LG
- Sino Biological Cell Lysates for FLT3LG
- ProSpec Recombinant Proteins for FLT3LG
-
ProSci Proteins for FLT3LG
- fms-related tyrosine kinase 3 ligand [90-300]
- fms related tyrosine kinase 3 ligand [91-779]
- fms-related tyrosine kinase 3 ligand [40-286]
- fms-related tyrosine kinase 3 ligand [96-321]
- fms-related tyrosine kinase 3 ligand [96-322]
- fms-related tyrosine kinase 3 ligand [40-590]
- FMS-like tyrosine kinase 3 ligand [40-443]
- FMS-like tyrosine kinase 3 ligand [92-587]
- FMS-like tyrosine kinase 3 ligand [91-820]
-
Abcam proteins for FLT3LG
Assay Products
- RayBiotech Human Flt-3 L ELISA
- Creative Diagnostics Mouse Flt-3 Ligand ELISA Kit and Human Flt-3L ELISA kit
- antibodies-online: Show 82 available FLT3LG Elisa Kits ranked by validation data
- Compare Top FLT3LG Elisa Kits
-
Quality Products:
- ABIN1114953
- ABIN924848
- ABIN365795
- ABIN414375
- ABIN1028663
- ABIN1889291
- ABIN624980
- ABIN1979559
- ABIN3032922
- ABIN5524520
- ABIN6720479
- ABIN1114955
- ABIN1889292
- ABIN415369
- ABIN625255
- ABIN1569870
- ABIN3032802
- ABIN1081455
- ABIN5524521
- ABIN4368185
- ABIN5524524
- ABIN627017
- ABIN2748107
- ABIN6385941
- ABIN4969224
- ABIN5072019
-
Abcam assays for FLT3LG
No data available for DME Specific Peptides for FLT3LG Gene
Domains & Families for FLT3LG Gene
Gene Families for FLT3LG Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
Protein Domains for FLT3LG Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FLT3LG Gene
- GenScript: Design optimal peptide antigens:
-
- FLT3LG protein (B7ZLY4_HUMAN)
- SL cytokine (FLT3L_HUMAN)
- cDNA FLJ61175, highly similar to SL cytokine (Q05C96_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FLT3LG Gene
Function for FLT3LG Gene
Molecular function for FLT3LG Gene
- UniProtKB/Swiss-Prot Function:
- Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.
- GENATLAS Biochemistry:
- FLT3 ligand,stimulating proliferation of hematopoietic cells
LifeMap Function Summary for FLT3LG Gene
It affects the following cells:
- Blood
FLT3LG as growth factor is involved in stem cell differentiation protocols towards the derivation of the following cells:
- Blood
- Adipose
-
and also in
- ADAtransduced hematopoietic stem cells
- Brown adipocyte-like cells
- Embryoid bodies
- Enriched hematopoietic progenitors
- Erythroid progenitors
- Hematopoietic progenitor cells
- Hematopoietic progenitor cells
- Hematopoietic-like progenitor cells
- IGFII- induced cells
- IGFII- induced cells
- Mast cell progenitor cells
- Megakaryocytes-like cells
- Mixed hematopoietic progenitor cells
- Mixed hematopoietic progenitor cells
- Natural killer-like cells
- Spheres
Phenotypes From GWAS Catalog for FLT3LG Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | signaling receptor binding | TAS | 8180375 |
| GO:0005125 | cytokine activity | IEA | -- |
| GO:0030971 | receptor tyrosine kinase binding | IBA | 21873635 |
Phenotypes for FLT3LG Gene
- MGI mutant phenotypes for FLT3LG:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for FLT3LG:
-
- Synthetic lethal with imatinib mesylate
- Dynamic nuclei (hole, folded or small irregular)
- Negative genetic interaction between KRASG13D/+ and KRAS+/-
- Reduced mammosphere formation
- Decreased Hepatitis C Virus pseudoparticles (HCVpp; H77; genotype 1a) infection
- Decreased cella89culturea89derived Hepatitis C virus (HCVcc; Luca89Jc1) infection
- Decreased viability
- no effect
- Increased vaccinia virus (VACV) infection
- Mildly decreased CFP-tsO45G cell surface transport
- Decreased IL-8 secretion
- Increased transferrin (TF) endocytosis
Animal Models for FLT3LG Gene
- MGI Knock Outs for FLT3LG:
-
- Flt3l Flt3l<tm1Imx>
Animal Model Products
-
Taconic Biosciences Mouse Models for FLT3LG
CRISPR Products
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-
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miRNA Products
Inhibitory RNA Products
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Clone Products
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-
- MG201410
- MG227308
- MR201410
- MR201410L3
- MR201410L4
- MR227308
- MR227308L1
- MR227308L2
- MR227308L3
- MR227308L4
- RC222242
- RC222242L1
- RC222242L2
- RC222242L3
- RC222242L4
- RC233505
- RC233506
- RC236103
- RC236104
- RG222242
- RG233505
- RG233506
- MR201410L3V
- MR201410L4V
- MR227308L1V
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- RC222242L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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Cell Line Products
-
Horizon Cell Lines for FLT3LG
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for FLT3LG Gene
Localization for FLT3LG Gene
Subcellular locations from UniProtKB/Swiss-Prot for FLT3LG Gene
- [Isoform 1]: Cell membrane; Single-pass type I membrane protein.
- [Isoform 2]: Secreted.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytosol | 3 |
| cytoskeleton | 2 |
| nucleus | 2 |
| endosome | 2 |
| lysosome | 2 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005886 | plasma membrane | IEA | -- |
| GO:0009986 | cell surface | IBA | 21873635 |
| GO:0016020 | membrane | NAS,IEA | 8145851 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for FLT3LG Gene
Pathways & Interactions for FLT3LG Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Cytokine Signaling in Immune system | ||
| 2 | Hematopoietic cell lineage | ||
| 3 | MAPK signaling pathway | ||
| 4 | Pathways in cancer | ||
| 5 | PI3K-Akt signaling pathway | ||
Pathways by source for FLT3LG Gene
2 BioSystems pathways for FLT3LG Gene
3 Reactome pathways for FLT3LG Gene
5 KEGG pathways for FLT3LG Gene
1 GeneGo (Thomson Reuters) pathway for FLT3LG Gene
- Development Flt3 signaling
3 R&D Systems pathways for FLT3LG Gene
1 Qiagen pathway for FLT3LG Gene
- FLT3 Signaling
Interacting Proteins for FLT3LG Gene
GPS-Prot Interaction Network for FLT3LG
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0001934 | positive regulation of protein phosphorylation | IEA | -- |
| GO:0007165 | signal transduction | TAS,IEA | 8180375 |
| GO:0008284 | positive regulation of cell proliferation | IDA,IBA | 8180375 |
| GO:0019221 | cytokine-mediated signaling pathway | TAS | -- |
Drugs & Compounds for FLT3LG Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
- Creative Biomart Recombinant Human Fms-related Tyrosine Kinase 3 Ligand
Transcripts for FLT3LG Gene
mRNA/cDNA for FLT3LG Gene
- 5 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 12 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000204637 1046 bps (ENST00000204637.6)
- ENST00000593422 563 bps (ENST00000593422.5)
- ENST00000594009 1076 bps (ENST00000594009.5)
- ENST00000595510 1301 bps (ENST00000595510.1)
- ENST00000596435 1034 bps (ENST00000596435.5)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for FLT3LG - Select products 50% OFF >
- * FLT3LG CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for FLT3LG
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FLT3LG
- genomics-online: gRNA clones - Search for available FLT3LG gRNA products
- Overview of 112 available FLT3LG gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for FLT3LG
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FLT3LG
- Browse OriGene Inhibitory RNA Products For FLT3LG
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Clone Products
- Applied Biological Materials (abm): Clones for FLT3LG - Select products 50% OFF >
- * FLT3LG as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG201410
- MG227308
- MR201410
- MR201410L3
- MR201410L4
- MR227308
- MR227308L1
- MR227308L2
- MR227308L3
- MR227308L4
- RC222242
- RC222242L1
- RC222242L2
- RC222242L3
- RC222242L4
- RC233505
- RC233506
- RC236103
- RC236104
- RG222242
- RG233505
- RG233506
- MR201410L3V
- MR201410L4V
- MR227308L1V
- MR227308L2V
- MR227308L3V
- MR227308L4V
- RC222242L1V
- RC222242L2V
- RC222242L3V
- RC222242L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for FLT3LG
- Addgene plasmids for FLT3LG
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FLT3LG
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | |||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||
| SP3: | - |
Relevant External Links for FLT3LG Gene
- GeneLoc Exon Structure for
- FLT3LG
Expression for FLT3LG Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Thymus (Hematopoietic System)
- T Helper Cells Thymus
- T-Cytotoxic Cells Thymus
-
Blood (Cardiovascular System)
- T Helper Cells Thymus
- T-Cytotoxic Cells Thymus
-
Eye (Sensory Organs)
mRNA differential expression in normal tissues according to GTEx for FLT3LG Gene
This gene is overexpressed in Whole Blood (x5.9).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FLT3LG
SOURCE GeneReport for Unigene cluster for FLT3LG Gene:
Hs.428Evidence on tissue expression from TISSUES for FLT3LG Gene
- Spleen(4.7)
- Nervous system(4.2)
- Lymph node(3.3)
- Bone marrow(2.8)
- Blood(2.6)
- Lung(2)
Primer Products
-
OriGene qPCR primer pairs for FLT3LG
-
OriGene qPCR primer pairs and template standards for FLT3LG
- genomics-online: primer clones - Search for available FLT3LG Primer products
- Overview of 112 available FLT3LG gene related products
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FLT3LG Gene
Orthologs for FLT3LG Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | FLT3LG 31 30 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | FLT3LG 31 30 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | FLT3LG 31 30 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | LOC102547607 30 |
|
||
| mouse (Mus musculus) |
Mammalia | Flt3l 17 31 30 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | FLT3LG 31 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | FLT3LG 31 |
|
OneToOne |
- Species where no ortholog for FLT3LG was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Evolution for FLT3LG Gene
- ENSEMBL:
- Gene Tree for FLT3LG (if available)
- TreeFam:
- Gene Tree for FLT3LG (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for FLT3LG: view image
Paralogs for FLT3LG Gene
(4) SIMAP similar genes for FLT3LG Gene using alignment to 7 proteins:
- FLT3L_HUMAN
- B7ZLY4_HUMAN
- M0QXI0_HUMAN
- M0QYM9_HUMAN
- M0R2K0_HUMAN
- M0R3A6_HUMAN
- Q05C96_HUMAN
No data available for Paralogs for FLT3LG Gene
Variants for FLT3LG Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FLT3LG Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 780580 | Benign: not provided | 49,474,672(+) | A/G | SYNONYMOUS_VARIANT,FIVE_PRIME_UTR_VARIANT |
Residual Variation Intolerance Score:
57.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.38;
8.28% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FLT3LG Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FLT3LG
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FLT3LG Gene
Disorders for FLT3LG Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| aplastic anemia |
|
|
| severe combined immunodeficiency |
|
|
| duodenum adenoma |
|
|
| myelodysplastic syndrome |
|
|
| brain cancer |
|
Search FLT3LG in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for FLT3LG
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for FLT3LG Gene
Publications for FLT3LG Gene
- Flt3 ligand structure and unexpected commonalities of helical bundles and cystine knots. (PMID: 10881197) Savvides SN … Andrew Karplus P (Nature structural biology 2000) 3 4 23 54
- Ligand for FLT3/FLK2 receptor tyrosine kinase regulates growth of haematopoietic stem cells and is encoded by variant RNAs. (PMID: 8145851) Hannum C … Mattson J (Nature 1994) 2 3 4 54
- Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". (PMID: 20628624) Johnatty SE … Australian Cancer Study (Ovarian Cancer) (PLoS genetics 2010) 3 41 54
- Human Flt-3-ligand-mobilized dendritic cells require additional activation to drive effective immune responses. (PMID: 17949888) Diener KR … Hayball JD (Experimental hematology 2008) 3 23 54
- Increased blood myeloid dendritic cells and dendritic cell-poietins in Langerhans cell histiocytosis. (PMID: 15728521) Rolland A … Palucka AK (Journal of immunology (Baltimore, Md. : 1950) 2005) 3 23 54
ExternalLinks
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- Browse OriGene Inhibitory RNA Products For FLT3LG
- OriGene qPCR primer pairs for FLT3LG
- OriGene qPCR primer pairs and template standards for FLT3LG
- OriGene CRISPR knockouts for FLT3LG
- MG201410
- MG227308
- MR201410
- MR201410L3
- MR201410L4
- MR227308
- MR227308L1
- MR227308L2
- MR227308L3
- MR227308L4
- RC222242
- RC222242L1
- RC222242L2
- RC222242L3
- RC222242L4
- RC233505
- RC233506
- RC236103
- RC236104
- RG222242
- RG233505
- RG233506
- MR201410L3V
- MR201410L4V
- MR227308L1V
- MR227308L2V
- MR227308L3V
- MR227308L4V
- RC222242L1V
- RC222242L2V
- RC222242L3V
- RC222242L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FLT3LG
- Sino Biological Human cDNA Clone for FLT3LG
- Sino Biological Recombinant Proteins for FLT3LG
- Sino Biological Cell Lysates for FLT3LG
- Sino Biological Antibodies for FLT3LG
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for FLT3LG
- Novus Biologicals proteins and lysates for FLT3LG
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- Abcam antibodies for FLT3LG
- Abcam proteins for FLT3LG
- Abcam assays for FLT3LG
- Find your target
- Browse Primary Antibodies
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- ProSpec Recombinant Proteins for FLT3LG
- Taconic Biosciences Mouse Models for FLT3LG
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for FLT3LG (AFLGC-FLT3LG)
- VectorBuilder Custom and pre-made DNA vectors for FLT3LG (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for FLT3LG (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for FLT3LG (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for FLT3LG CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for FLT3LG
- Addgene plasmids for FLT3LG
- antibodies-online: Show 25 available FLT3LG Antibodies ranked by validation data
- Compare Top FLT3LG Antibodies
- antibodies-online: Show 82 available FLT3LG Elisa Kits ranked by validation data
- Compare Top FLT3LG Elisa Kits
- Quality Products:
- ABIN1114953
- ABIN924848
- ABIN365795
- ABIN414375
- ABIN1028663
- ABIN1889291
- ABIN624980
- ABIN1979559
- ABIN3032922
- ABIN5524520
- ABIN6720479
- ABIN1114955
- ABIN1889292
- ABIN415369
- ABIN625255
- ABIN1569870
- ABIN3032802
- ABIN1081455
- ABIN5524521
- ABIN4368185
- ABIN5524524
- ABIN627017
- ABIN2748107
- ABIN6385941
- ABIN4969224
- ABIN5072019
- antibodies-online: Show 102 available FLT3LG Proteins ranked by validation data
- Compare Top FLT3LG Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for FLT3LG
- Search Santa Cruz Biotechnology (SCBT) for FLT3LG siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FLT3LG
- Custom Antibody ServicesProSci Antibodies for FLT3LG
- ProSci Proteins for FLT3LG
- fms-related tyrosine kinase 3 ligand [90-300]
- fms related tyrosine kinase 3 ligand [91-779]
- fms-related tyrosine kinase 3 ligand [40-286]
- fms-related tyrosine kinase 3 ligand [96-321]
- fms-related tyrosine kinase 3 ligand [96-322]
- fms-related tyrosine kinase 3 ligand [40-590]
- FMS-like tyrosine kinase 3 ligand [40-443]
- FMS-like tyrosine kinase 3 ligand [92-587]
- FMS-like tyrosine kinase 3 ligand [91-820]
- Horizon Cell Lines for FLT3LG
- genomics-online: cdna clones - Search for available FLT3LG CDNA products
- Overview of 112 available FLT3LG gene related products
- orf clones - Search for available FLT3LG ORF products
- Overview of 112 available FLT3LG gene related products
- genomics-online: gRNA clones - Search for available FLT3LG gRNA products
- Overview of 112 available FLT3LG gene related products
- genomics-online: primer clones - Search for available FLT3LG Primer products
- Overview of 112 available FLT3LG gene related products
- genomics-online: shRNA clones - Search for available FLT3LG shRNA products
- Overview of 112 available FLT3LG gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FLT3LG
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FLT3LG
- Search GeneCopoeia for miRNA 3'UTR Target clone products for FLT3LG
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FLT3LG
- Biorbyt antibodies for FLT3LG
Sources for FLT3LG Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16)