External Ids for FLOT1 Gene
Previous GeneCards Identifiers for FLOT1 Gene
This gene encodes an protein that localizes to the caveolae, which are small domains on the inner cell membranes. This protein plays a role in vesicle trafficking and cell morphology. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for FLOT1 Gene
FLOT1 (Flotillin 1) is a Protein Coding gene. Diseases associated with FLOT1 include Mycobacterium Marinum. Among its related pathways are Cytoskeletal Signaling and Regulation of lipid metabolism Insulin signaling-generic cascades. Gene Ontology (GO) annotations related to this gene include protease binding and ionotropic glutamate receptor binding. An important paralog of this gene is FLOT2.
UniProtKB/Swiss-Prot for FLOT1 Gene
May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles.