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Aliases for FLG-AS1 Gene

Subcategory (RNA class) for FLG-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for FLG-AS1 Gene

  • FLG Antisense RNA 1 2 3 5
  • FLG Antisense RNA 1 (Non-Protein Coding) 2 3

External Ids for FLG-AS1 Gene

Previous GeneCards Identifiers for FLG-AS1 Gene

  • GC01P152168

Summaries for FLG-AS1 Gene

GeneCards Summary for FLG-AS1 Gene

FLG-AS1 (FLG Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with FLG-AS1 include Dermatitis, Atopic, 2.

Additional gene information for FLG-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FLG-AS1 Gene

Genomics for FLG-AS1 Gene

GeneHancer (GH) Regulatory Elements for FLG-AS1 Gene

Promoters and enhancers for FLG-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J152166 Enhancer 1 Ensembl ENCODE 659.1 -0.4 -365 1.7 HDAC1 NFIB RFX5 ZEB1 RCOR1 FOS RXRA CEBPB NR2F2 SP1 FLG-AS1 ENSG00000229021 RPTN PUDPP2
GH01J152045 Promoter/Enhancer 2.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 16 -119.5 -119521 6.6 HDGF PKNOX1 CLOCK ARNT ARID4B NEUROD1 SIN3A YBX1 FEZF1 DMAP1 S100A11 LOC101927949 PI4KB ZNF687 PIP5K1A MRPL9 ENSG00000229021 FLG-AS1 GABPB2 RPS10P6
GH01J152188 Promoter/Enhancer 1.3 Ensembl ENCODE 29.2 +21.0 20988 1.4 PKNOX1 SIN3A BMI1 RAD21 YY1 ZNF335 SCRT2 ZNF207 ZNF143 RCOR1 FLG-AS1 HRNR FLG PIR41917 PUDPP2
GH01J151940 Enhancer 1.8 FANTOM5 Ensembl ENCODE dbSUPER 12.8 -224.0 -224027 7.6 PKNOX1 CLOCK FOXA2 NEUROD1 SIN3A FEZF1 ZNF2 ZBTB7B ZNF416 FOS POGZ GABPB2 PI4KB MRPL9 PIP5K1A LYSMD1 ENSG00000229021 HRNR THEM4 C1orf56
GH01J151324 Promoter/Enhancer 2.2 EPDnew Ensembl ENCODE dbSUPER 9.8 -841.4 -841378 4.2 HDGF FOXA2 SMAD1 ARNT SIN3A DMAP1 YBX1 ZNF2 ZBTB7B YY1 PI4KB ENSG00000273481 RPRD2 GABPB2 MRPL9 PIP5K1A POGZ LYSMD1 HRNR FLG-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around FLG-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for FLG-AS1 Gene

Genomic Locations for FLG-AS1 Gene
chr1:152,168,125-152,445,456
(GRCh38/hg38)
Size:
277,332 bases
Orientation:
Plus strand
chr1:152,140,601-152,339,311
(GRCh37/hg19)
Size:
198,711 bases
Orientation:
Plus strand

Genomic View for FLG-AS1 Gene

Genes around FLG-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FLG-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FLG-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FLG-AS1 Gene

Function for FLG-AS1 Gene

Phenotypes From GWAS Catalog for FLG-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FLG-AS1 Gene

Localization for FLG-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FLG-AS1 Gene

Pathways & Interactions for FLG-AS1 Gene

SuperPathways for FLG-AS1 Gene

No Data Available

Interacting Proteins for FLG-AS1 Gene

Gene Ontology (GO) - Biological Process for FLG-AS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FLG-AS1 Gene

Drugs & Compounds for FLG-AS1 Gene

No Compound Related Data Available

Transcripts for FLG-AS1 Gene

mRNA/cDNA for FLG-AS1 Gene

(5) Additional mRNA sequences :
(9) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(10) RNA Central transcripts :

Unigene Clusters for FLG-AS1 Gene

FLG antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FLG-AS1 Gene

No ASD Table

Relevant External Links for FLG-AS1 Gene

GeneLoc Exon Structure for
FLG-AS1
ECgene alternative splicing isoforms for
FLG-AS1

Expression for FLG-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FLG-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for FLG-AS1 Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x4.4).

SOURCE GeneReport for Unigene cluster for FLG-AS1 Gene:

Hs.23783
genes like me logo Genes that share expression patterns with FLG-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FLG-AS1 Gene

Orthologs for FLG-AS1 Gene

Evolution for FLG-AS1 Gene

ENSEMBL:
Gene Tree for FLG-AS1 (if available)
TreeFam:
Gene Tree for FLG-AS1 (if available)

No data available for Orthologs for FLG-AS1 Gene

Paralogs for FLG-AS1 Gene

No data available for Paralogs for FLG-AS1 Gene

Variants for FLG-AS1 Gene

Sequence variations from dbSNP and Humsavar for FLG-AS1 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs1060499587 likely-pathogenic, Ichthyosis vulgaris 152,313,983(+) CCTGTCCTG/CCTG genic_upstream_transcript_variant, non_coding_transcript_variant
rs558269137 pathogenic, risk-factor, uncertain-significance, likely-benign, Ichthyosis vulgaris, Dermatitis, atopic, 2, susceptibility to, Dermatitis, atopic, 2, not specified, not provided 152,312,601(+) ACTGACTG/ACTG upstream_transcript_variant
rs61816761 pathogenic, risk-factor, Ichthyosis vulgaris, Dermatitis, atopic, 2, susceptibility to, not provided 152,313,385(+) G/A/T upstream_transcript_variant
rs797045090 pathogenic, Ichthyosis vulgaris 152,312,743(+) G/A upstream_transcript_variant
rs1064796274 pathogenic, not provided 152,311,980(+) TTT/TT upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for FLG-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv200n106 CNV duplication 24896259
esv2043587 CNV deletion 18987734
esv25681 CNV loss 19812545
esv2593579 CNV deletion 19546169
esv2663079 CNV deletion 23128226
esv2664011 CNV deletion 23128226
esv2718140 CNV deletion 23290073
esv2718151 CNV deletion 23290073
esv3540790 CNV deletion 23714750
esv3578178 CNV loss 25503493
esv3587546 CNV gain 21293372
esv3587547 CNV loss 21293372
nsv1014095 CNV gain 25217958
nsv1075398 CNV duplication 25765185
nsv1147169 CNV duplication 26484159
nsv471348 CNV gain 19718026
nsv952208 CNV deletion 24416366
nsv998298 CNV loss 25217958

Additional Variant Information for FLG-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FLG-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FLG-AS1 Gene

Disorders for FLG-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for FLG-AS1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
dermatitis, atopic, 2
  • atod2
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for FLG-AS1

genes like me logo Genes that share disorders with FLG-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for FLG-AS1 Gene

Publications for FLG-AS1 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  2. Genetic variants associated with disordered eating. (PMID: 23568457) Wade TD … Martin NG (The International journal of eating disorders 2013) 3 58
  3. Genome-wide association study identifies two new susceptibility loci for atopic dermatitis in the Chinese Han population. (PMID: 21666691) Sun LD … Zhang XJ (Nature genetics 2011) 3 58
  4. A genome-wide association study of Cloninger's temperament scales: implications for the evolutionary genetics of personality. (PMID: 20691247) Verweij KJ … Wray NR (Biological psychology 2010) 3 58
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for FLG-AS1 Gene

Sources for FLG-AS1 Gene

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