Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FKBP1C Gene

Aliases for FKBP1C Gene

  • FK506 Binding Protein 1C 2 3 5

External Ids for FKBP1C Gene

Previous GeneCards Identifiers for FKBP1C Gene

  • GC06P063918
  • GC06P063979
  • GC06P063921
  • GC06P061101

Summaries for FKBP1C Gene

GeneCards Summary for FKBP1C Gene

FKBP1C (FK506 Binding Protein 1C) is a Pseudogene. Gene Ontology (GO) annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and calcium channel inhibitor activity. An important paralog of this gene is FKBP1A.

Additional gene information for FKBP1C Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FKBP1C Gene

Genomics for FKBP1C Gene

GeneHancer (GH) Regulatory Elements for FKBP1C Gene

Promoters and enhancers for FKBP1C Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I063236 Enhancer 0.4 ENCODE 12.1 +25.2 25225 0.2 CTCF SP1 IKZF1 FKBP1C LGSN LOC100128610 GC06P063252 GC06P062882 GC06P062883 GC06P062884 GC06P062885
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FKBP1C on UCSC Golden Path with GeneCards custom track

Genomic Locations for FKBP1C Gene

Genomic Locations for FKBP1C Gene
1,579 bases
Plus strand

Genomic View for FKBP1C Gene

Genes around FKBP1C on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FKBP1C Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FKBP1C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FKBP1C Gene

Proteins for FKBP1C Gene

  • Protein details for FKBP1C Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Peptidylprolyl isomerase
    Protein Accession:

    Protein attributes for FKBP1C Gene

    108 amino acids
    Molecular mass:
    12179 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FKBP1C Gene

Post-translational modifications for FKBP1C Gene

No Post-translational modifications

Other Protein References for FKBP1C Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for FKBP1C Gene

Domains & Families for FKBP1C Gene

Gene Families for FKBP1C Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FKBP1C Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with FKBP1C: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for FKBP1C Gene

Function for FKBP1C Gene

Gene Ontology (GO) - Molecular Function for FKBP1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003755 peptidyl-prolyl cis-trans isomerase activity IBA --
GO:0005528 FK506 binding IBA --
GO:0016853 isomerase activity IEA --
genes like me logo Genes that share ontologies with FKBP1C: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FKBP1C Gene

Localization for FKBP1C Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FKBP1C gene
Compartment Confidence
cytosol 4
plasma membrane 2
extracellular 2
nucleus 2
endoplasmic reticulum 2
cytoskeleton 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for FKBP1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IBA --
genes like me logo Genes that share ontologies with FKBP1C: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for FKBP1C Gene

Pathways & Interactions for FKBP1C Gene

SuperPathways for FKBP1C Gene

No Data Available

Interacting Proteins for FKBP1C Gene

Gene Ontology (GO) - Biological Process for FKBP1C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0061077 chaperone-mediated protein folding IBA --
genes like me logo Genes that share ontologies with FKBP1C: view

No data available for Pathways by source and SIGNOR curated interactions for FKBP1C Gene

Drugs & Compounds for FKBP1C Gene

No Compound Related Data Available

Transcripts for FKBP1C Gene

mRNA/cDNA for FKBP1C Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FKBP1C Gene

No ASD Table

Relevant External Links for FKBP1C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FKBP1C Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FKBP1C Gene

Protein differential expression in normal tissues from HIPED for FKBP1C Gene

This gene is overexpressed in Heart (57.4) and Brain (11.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from PaxDb and MOPED for FKBP1C Gene

Protein tissue co-expression partners for FKBP1C Gene

NURSA nuclear receptor signaling pathways regulating expression of FKBP1C Gene:


Evidence on tissue expression from TISSUES for FKBP1C Gene

  • Blood(3)
  • Muscle(2.9)
  • Nervous system(2.8)
  • Heart(2.5)
  • Kidney(2.4)
  • Spleen(2.2)
  • Adrenal gland(2.1)
  • Liver(2)
genes like me logo Genes that share expression patterns with FKBP1C: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FKBP1C Gene

Orthologs for FKBP1C Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for FKBP1C Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia -- 34
  • 96 (a)
(Bos Taurus)
Mammalia FKBP1A 34
  • 93 (a)
(Mus musculus)
Mammalia Fkbp1a 34
  • 93 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 89 (a)
-- 34
  • 75 (a)
-- 34
  • 74 (a)
(Gallus gallus)
Aves FKBP12 34
  • 90 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 88 (a)
(Danio rerio)
Actinopterygii fkbp1aa 34
  • 76 (a)
fruit fly
(Drosophila melanogaster)
Insecta FK506-bp2 34
  • 71 (a)
(Caenorhabditis elegans)
Secernentea fkb-8 34
  • 16 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes FPR1 34
  • 53 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.3865 34
  • 70 (a)
Species where no ortholog for FKBP1C was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for FKBP1C Gene

Gene Tree for FKBP1C (if available)
Gene Tree for FKBP1C (if available)

Paralogs for FKBP1C Gene

Paralogs for FKBP1C Gene Pseudogenes for FKBP1C Gene

genes like me logo Genes that share paralogs with FKBP1C: view

Variants for FKBP1C Gene

Variation tolerance for FKBP1C Gene

Gene Damage Index Score: 0.56; 12.01% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for FKBP1C Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for FKBP1C Gene

Disorders for FKBP1C Gene

No disorders were found for FKBP1C Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for FKBP1C Gene

Publications for FKBP1C Gene

No publications were found for FKBP1C Gene.

Products for FKBP1C Gene

Sources for FKBP1C Gene

Loading form....