Aliases for FILIP1 Gene
External Ids for FILIP1 Gene
Previous GeneCards Identifiers for FILIP1 Gene
This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016]
GeneCards Summary for FILIP1 Gene
FILIP1 (Filamin A Interacting Protein 1) is a Protein Coding gene. Diseases associated with FILIP1 include Ureterocele and Periventricular Nodular Heterotopia. Among its related pathways are Integrated Breast Cancer Pathway. An important paralog of this gene is FILIP1L.
UniProtKB/Swiss-Prot Summary for FILIP1 Gene
By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A.