Aliases for FGF7 Gene
External Ids for FGF7 Gene
Previous GeneCards Identifiers for FGF7 Gene
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]
GeneCards Summary for FGF7 Gene
FGF7 (Fibroblast Growth Factor 7) is a Protein Coding gene. Diseases associated with FGF7 include Mucositis and Apert Syndrome. Among its related pathways are Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway and RET signaling. Gene Ontology (GO) annotations related to this gene include growth factor activity and chemoattractant activity. An important paralog of this gene is FGF10.
UniProtKB/Swiss-Prot Summary for FGF7 Gene
Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.