Aliases for FGF6 Gene
External Ids for FGF6 Gene
Previous GeneCards Identifiers for FGF6 Gene
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008]
GeneCards Summary for FGF6 Gene
FGF6 (Fibroblast Growth Factor 6) is a Protein Coding gene. Diseases associated with FGF6 include Apert Syndrome and Breast Cancer. Among its related pathways are FGFR1 mutant receptor activation and RET signaling. Gene Ontology (GO) annotations related to this gene include growth factor activity and fibroblast growth factor receptor binding. An important paralog of this gene is FGF4.
UniProtKB/Swiss-Prot Summary for FGF6 Gene
Plays an important role in the regulation of cell proliferation, cell differentiation, angiogenesis and myogenesis, and is required for normal muscle regeneration.