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The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor bu... See more...
Aliases for FGF20 Gene
External Ids for FGF20 Gene
- HGNC: 3677
- NCBI Entrez Gene: 26281
- Ensembl: ENSG00000078579
- OMIM®: 605558
- UniProtKB/Swiss-Prot: Q9NP95
Previous GeneCards Identifiers for FGF20 Gene
- GC08M016743
- GC08M016930
- GC08M016860
- GC08M016894
- GC08M015395
Summaries for FGF20 Gene
-
The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility. [provided by RefSeq, Oct 2009]
GeneCards Summary for FGF20 Gene
FGF20 (Fibroblast Growth Factor 20) is a Protein Coding gene. Diseases associated with FGF20 include Renal Hypodysplasia/Aplasia 2 and Renal Agenesis, Bilateral. Among its related pathways are Downstream signaling events of B Cell Receptor (BCR) and ERK Signaling. Gene Ontology (GO) annotations related to this gene include growth factor activity and fibroblast growth factor receptor binding. An important paralog of this gene is FGF9.
UniProtKB/Swiss-Prot Summary for FGF20 Gene
-
Neurotrophic factor that regulates central nervous development and function.
Additional gene information for FGF20 Gene
- HGNC (3677)
- NCBI Entrez Gene (26281)
- Ensembl (ENSG00000078579)
- OMIM® (605558)
- UniProtKB/Swiss-Prot (Q9NP95)
- Open Targets Platform(ENSG00000078579)
- Monarch Initiative
- Search for FGF20 at DataMed
- Search for FGF20 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FGF20 Gene
Genomics for FGF20 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for FGF20 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around FGF20 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FGF20
- Top Transcription factor binding sites by QIAGEN in the FGF20 gene promoter:
-
- Cdc5
- E2F
- E2F-1
- Evi-1
- Meis-1
- Meis-1a
- Meis-1b
- MyoD
- Nkx2-5
Genomic Locations for FGF20 Gene
Latest Assembly
- chr8:16,992,181-17,002,345
- (GRCh38/hg38)
- Size:
- 10,165 bases
- Orientation:
- Minus strand
Previous Assembly
- chr8:16,849,690-16,859,854
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 10,165 bases
- Orientation:
- Minus strand
- chr8:16,849,678-16,859,690
- (GRCh37/hg19 by Ensembl)
- Size:
- 10,013 bases
- Orientation:
- Minus strand
Genomic View for FGF20 Gene
Genes around FGF20 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8p22 by HGNC
- 8p22 by Entrez Gene
- 8p22 by Ensembl
FGF20 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FGF20 Gene
Proteins for FGF20 Gene
-
Protein details for FGF20 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9NP95-FGF20_HUMAN
- Recommended name:
- Fibroblast growth factor 20
- Protein Accession:
- Q9NP95
- B2RPH5
Protein attributes for FGF20 Gene
- Size:
- 211 amino acids
- Molecular mass:
- 23499 Da
- Quaternary structure:
-
- Homodimer. Interacts with FGFR2 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors.
Post-translational modifications for FGF20 Gene
Other Protein References for FGF20 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- G Biosciences Immunotag™ FGF20 Antibody
- Novus Biologicals Antibodies for FGF20
-
Abcam antibodies for FGF20
- Invitrogen Antibodies for FGF20 (AFLGC-FGF20)
- antibodies-online: Show 14 available FGF20 Antibodies ranked by validation data
- Compare Top FGF20 Antibodies
-
Recommended
- 25 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 2 IHC Antibodies (anti-human)
- 30 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 1 IHC (p) Antibody (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 12 WB Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
-
Boster Bio Antibodies for FGF20
-
Custom Antibody ServicesProSci Antibodies for FGF20
-
Santa Cruz Biotechnology (SCBT) Antibodies for FGF20
Protein products for research
-
OriGene Purified Proteins for FGF20
- Search Origene for MassSpec and Protein Over-expression Lysates for FGF20
- Origene Custom Protein Services for FGF20
- ProSpec Recombinant Proteins for FGF20
-
ProSci Proteins for FGF20
-
Abcam proteins for FGF20
No data available for DME Specific Peptides for FGF20 Gene
Domains & Families for FGF20 Gene
Gene Families for FGF20 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Disease related genes
- Plasma proteins
- Predicted intracellular proteins
- Predicted secreted proteins
Protein Domains for FGF20 Gene
- InterPro:
- Blocks:
-
- Heparin binding growth factor family signature
- IL1/HBGF family signature
- ProtoNet:
Suggested Antigen Peptide Sequences for FGF20 Gene
- GenScript: Design optimal peptide antigens:
-
- Fibroblast growth factor 20 (B2RPH5_HUMAN)
- Fibroblast growth factor 20 (FGF20_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9NP95- Family:
-
- Belongs to the heparin-binding growth factors family.
Function for FGF20 Gene
Molecular function for FGF20 Gene
- UniProtKB/Swiss-Prot Function:
- Neurotrophic factor that regulates central nervous development and function.
LifeMap Function Summary for FGF20 Gene
During embryonic development, FGF20 as signaling molecule is secreted from the following cells
- Tooth
It affects the following cells:
- Head Mesenchyme
Phenotypes From GWAS Catalog for FGF20 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005102 | signaling receptor binding | TAS | 11306498 |
| GO:0005104 | fibroblast growth factor receptor binding | IEA,IBA | 21873635 |
| GO:0008083 | growth factor activity | IEA,ISS | -- |
| GO:0043395 | heparan sulfate proteoglycan binding | TAS | 11306498 |
| GO:0090722 | receptor-receptor interaction | IDA | 24157794 |
Phenotypes for FGF20 Gene
- MGI mutant phenotypes for FGF20:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for FGF20:
Animal Models for FGF20 Gene
- MGI Knock Outs for FGF20:
-
- Fgf20 Fgf20<tm1.1Dor>
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for FGF20 - Starting at $85 >
- * FGF20 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for FGF20
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FGF20
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGF20
miRNA for FGF20 Gene
- miRTarBase miRNAs that target FGF20
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FGF20
- Browse OriGene Inhibitory RNA Products For FGF20
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FGF20
Clone products for research
- Applied Biological Materials (abm): Clones for FGF20 - Starting at $45 >
- * FGF20 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for FGF20
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FGF20
Cell Lines for research
-
Horizon Cell Lines for FGF20
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for FGF20 Gene
Localization for FGF20 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FGF20 Gene
- Secreted.
| Compartment | Confidence |
|---|---|
| extracellular | 4 |
| plasma membrane | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| cytosol | 2 |
| cytoskeleton | 1 |
| endosome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| peroxisome | 0 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | IEA,TAS | -- |
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005737 | cytoplasm | IBA | 21873635 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for FGF20 Gene
Pathways & Interactions for FGF20 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | RET signaling |
.92
|
.92
|
| 2 | Downstream signaling of activated FGFR2 | ||
| 3 | Apoptotic Pathways in Synovial Fibroblasts |
Cellular Apoptosis Pathway
.85
Mitochondrial Apoptosis
.85
Apoptotic Pathways in Synovial Fibroblasts
.84
p53 Mediated Apoptosis
.84
DHA Signaling
.74
Telomerase Components in Cell Signaling
.72
PPAR Pathway
.66
|
Rac1 Pathway
.65
Glioma Invasiveness
.64
Actin-Based Motility by Rho Family GTPases
.62
ERK5 Signaling
.61
eIF2 Pathway
.60
Rap1 Pathway
.57
Nuclear Receptor Activation by Vitamin-A
.57
|
| 4 | Negative regulation of FGFR1 signaling | ||
| 5 | GPCR Pathway |
Paxillin Interactions
.73
Ras Pathway
.73
GPCR Pathway
.62
Pancreatic Adenocarcinoma
.59
|
Breast Cancer Regulation by Stathmin1
.58
NFAT in Immune Response
.58
Estrogen Pathway
.55
P2Y Receptor Signaling
.38
|
Pathways by source for FGF20 Gene
1 BioSystems pathway for FGF20 Gene
108 Reactome pathways for FGF20 Gene
10 KEGG pathways for FGF20 Gene
59 Qiagen pathways for FGF20 Gene
- 14-3-3 Induced Intracellular Signaling
- Actin-Based Motility by Rho Family GTPases
- Activation of cAMP-Dependent PKA
- Activation of PKA through GPCR
- Activation of PKC through GPCR
Interacting Proteins for FGF20 Gene
GPS-Prot Interaction Network for FGF20
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000165 | MAPK cascade | TAS | -- |
| GO:0001934 | positive regulation of protein phosphorylation | IBA | 21873635 |
| GO:0007165 | signal transduction | TAS | 10913340 |
| GO:0007267 | cell-cell signaling | TAS | 10913340 |
| GO:0008284 | positive regulation of cell proliferation | IEA,TAS | 11306498 |
No data available for SIGNOR curated interactions for FGF20 Gene
Transcripts for FGF20 Gene
mRNA/cDNA for FGF20 Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000180166 1840 nts (view in UCSC)
- ENST00000519941 434 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for FGF20 - Starting at $85 >
- * FGF20 CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for FGF20
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FGF20
-
Santa Cruz Biotechnology (SCBT) CRISPR for FGF20
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FGF20
- Browse OriGene Inhibitory RNA Products For FGF20
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FGF20
Clone products for research
- Applied Biological Materials (abm): Clones for FGF20 - Starting at $45 >
- * FGF20 as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for FGF20
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FGF20
Relevant External Links for FGF20 Gene
- GeneLoc Exon Structure for
- FGF20
Expression for FGF20 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Skeletal Muscle (Muscoskeletal System)
- Mononuclear Myocytes Hyoid Arch Muscles
- Mononuclear Myocytes Mandibular Arch Muscles
-
Tooth (Integumentary System)
- Dental Placode Cells Dental Placode
-
Epithelial Cells
- Dental Placode Cells Dental Placode
-
Head Mesenchyme (Muscoskeletal System)
- Ectoderm Cells Branchial Arch 1
-
Ectoderm (Gastrulation Derivatives)
- Ectoderm Cells Branchial Arch 1
mRNA differential expression in normal tissues according to GTEx for FGF20 Gene
This gene is overexpressed in Brain - Spinal cord (cervical c-1) (x6.3), Brain - Cerebellar Hemisphere (x6.1), and Brain - Cerebellum (x5.2).
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FGF20
SOURCE GeneReport for Unigene cluster for FGF20 Gene:
Hs.199905mRNA Expression by UniProt/SwissProt for FGF20 Gene:
Q9NP95-FGF20_HUMAN
Tissue specificity:
Predominantly expressed in the cerebellum.
Evidence on tissue expression from TISSUES for FGF20 Gene
- Nervous system(4.4)
Phenotype-based relationships between genes and organs from Gene ORGANizer for FGF20 Gene
Germ Layers:
- ectoderm
- endoderm
- mesoderm
Systems:
- digestive
- integumentary
- nervous
- reproductive
- respiratory
- skeleton
- urinary
Regions:
Head and neck:
- chin
- ear
- eye
- eyelid
- face
- head
- jaw
- mandible
- maxilla
- mouth
- nose
- outer ear
- skull
Thorax:
- esophagus
- lung
- trachea
Abdomen:
- intestine
- kidney
- large intestine
- small intestine
- stomach
Pelvis:
- pelvis
- placenta
- urethra
- urinary bladder
- uterus
- vagina
General:
- skin
Primer products for research
-
OriGene qPCR primer pairs for FGF20
Gene Expression Assays for research
No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for FGF20 Gene
Orthologs for FGF20 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | FGF20 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | FGF20 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | FGF20 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Fgf20 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Fgf20 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | FGF20 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | FGF20 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | FGF20 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | fgf20 30 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.2769 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | fgf20a 31 |
|
OneToMany | |
| fgf20b 30 31 |
|
OneToMany | |||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CS-FGF9/16/20 31 |
|
OneToMany |
- Species where no ortholog for FGF20 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for FGF20 Gene
- ENSEMBL:
- Gene Tree for FGF20 (if available)
- TreeFam:
- Gene Tree for FGF20 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for FGF20: view image
Paralogs for FGF20 Gene
Paralogs for FGF20 Gene
(19) SIMAP similar genes for FGF20 Gene using alignment to 3 proteins:
- FGF20_HUMAN
- H0YAT9_HUMAN
- Q4V769_HUMAN
Variants for FGF20 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FGF20 Gene
| SNP ID | Clinical significance and condition | Chr 08 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs12720208 | Uncertain Significance: Parkinson disease, late-onset | 16,992,890(-) |
G/A NM_019851.3(FGF20):c.*182C>T |
THREE_PRIME_UTR | |
| rs1274005326 | Likely Benign: not provided | 17,001,955(-) |
C/T NM_019851.3(FGF20):c.78G>A (p.Leu26=) |
SYNONYMOUS | |
| rs1563235398 | Uncertain Significance: not provided | 17,001,931(-) |
CGG/TGT NM_019851.3(FGF20):c.100_102delinsACA (p.Pro34Thr) |
MISSENSE | |
| rs1585100306 | Likely Pathogenic: Renal hypodysplasia/aplasia 2 | 16,993,318(-) |
C/T NM_019851.3(FGF20):c.391-1G>A |
SPLICE_ACCEPTOR | |
| rs17514908 | Benign: not provided | 17,001,751(-) |
G/T NM_019851.3(FGF20):c.282C>A (p.Leu94=) |
SYNONYMOUS |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv250e55 | CNV | gain | 17911159 |
| esv2759599 | CNV | gain | 17122850 |
| esv3572602 | CNV | loss | 25503493 |
| nsv1018645 | CNV | gain | 25217958 |
| nsv8304 | CNV | gain+loss | 18304495 |
| nsv831243 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
68.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
3.99;
60.07% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FGF20 Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FGF20 Gene
Disorders for FGF20 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| renal hypodysplasia/aplasia 2 |
|
|
| renal agenesis, bilateral |
|
|
| renal hypodysplasia/aplasia 1 |
|
|
| bilateral renal aplasia |
|
|
| parkinson disease, late-onset |
|
|
Search FGF20 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FGF20_HUMAN- Renal hypodysplasia/aplasia 2 (RHDA2) [MIM:615721]: A perinatally lethal renal disease encompassing a spectrum of kidney development defects, including renal agenesis, bilateral renal aplasia, hypoplasia, (cystic) dysplasia, and severe obstructive uropathy. {ECO:0000269 PubMed:22698282}. Note=The disease is caused by variants affecting the gene represented in this entry.
Additional Disease Information for FGF20
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for Genatlas for FGF20 Gene
Publications for FGF20 Gene
- FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression. (PMID: 19133659) Wider C … Ross OA (Movement disorders : official journal of the Movement Disorder Society 2009) 3 4 23 41
- Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein. (PMID: 18252210) Wang G … Vance JM (American journal of human genetics 2008) 3 4 23 41
- Molecular cloning and characterization of human FGF-20 on chromosome 8p21.3-p22. (PMID: 10913340) Kirikoshi H … Katoh M (Biochemical and biophysical research communications 2000) 2 3 4 23
- FGF9 and FGF20 maintain the stemness of nephron progenitors in mice and man. (PMID: 22698282) Barak H … Kopan R (Developmental cell 2012) 3 4 74
- Homodimerization controls the fibroblast growth factor 9 subfamily's receptor binding and heparan sulfate-dependent diffusion in the extracellular matrix. (PMID: 19564416) Kalinina J … Mohammadi M (Molecular and cellular biology 2009) 3 4 23
ExternalLinks
Products for FGF20 Gene
- Custom Antibody Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for FGF20
- Origene Custom Protein Services for FGF20
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- Browse OriGene Inhibitory RNA Products For FGF20
- OriGene qPCR primer pairs for FGF20
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- Sino Biological Human cDNA Clone for FGF20
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- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
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- Novus Biologicals Antibodies for FGF20
- Novus Biologicals proteins and lysates for FGF20
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for FGF20
- Abcam proteins for FGF20
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
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- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
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- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for FGF20 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for FGF20 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for FGF20 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for FGF20 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for FGF20
- antibodies-online: Show 14 available FGF20 Antibodies ranked by validation data
- Compare Top FGF20 Antibodies
- Recommended
- 25 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 3 IHC (p) Antibodies (anti-human)
- 2 IHC Antibodies (anti-human)
- 30 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 1 IHC (p) Antibody (anti-mouse)
- 12 IF (p) Antibodies (anti-rat)
- 12 WB Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- 1 IHC (p) Antibody (anti-rat)
- antibodies-online: Show 15 available FGF20 Elisa Kits ranked by validation data
- Compare Top FGF20 Elisa Kits
- antibodies-online: Show 15 available FGF20 Proteins ranked by validation data
- Compare Top FGF20 Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for FGF20
- Search Santa Cruz Biotechnology (SCBT) for FGF20 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FGF20
- Custom Antibody ServicesProSci Antibodies for FGF20
- ProSci Proteins for FGF20
- Horizon Cell Lines for FGF20
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FGF20
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FGF20
- Search GeneCopoeia for miRNA 3'UTR Target clone products for FGF20
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FGF20
- Boster Bio Antibodies for FGF20
- Browse Boster Bio ELISA Kits
Sources for FGF20 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Mar-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) MedlinePlus Genetics
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNAcentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Open Targets Platform
- (175) 5SRRNADB
- (176) snoDB
- (177) MirGeneDB