External Ids for FGF17 Gene
Previous GeneCards Identifiers for FGF17 Gene
This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for FGF17 Gene
FGF17 (Fibroblast Growth Factor 17) is a Protein Coding gene. Diseases associated with FGF17 include Hypogonadotropic Hypogonadism 20 With Or Without Anosmia and Normosmic Congenital Hypogonadotropic Hypogonadism. Among its related pathways are FGFR1 mutant receptor activation and RET signaling. Gene Ontology (GO) annotations related to this gene include growth factor activity and type 2 fibroblast growth factor receptor binding. An important paralog of this gene is FGF8.
UniProtKB/Swiss-Prot Summary for FGF17 Gene
Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.