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FER1L4 Gene(Pseudogene)

Fer-1 Like Family Member 4, Pseudogene

GCID:
GC20M035558
GIFtS:
26
Genes Participants
UDN Logo

Aliases for FER1L4 Gene

Aliases for FER1L4 Gene

  • Fer-1 Like Family Member 4, Pseudogene 2 3 5
  • Fer-1 Like Family Member 4, Pseudogene (Functional) 2 3
  • C20orf124 3 4
  • Fer-1-Like 4 (C. Elegans), Pseudogene (Functional) 2
  • Fer-1-Like 4, Pseudogene (Functional) 3
  • Fer-1-Like 4 (C. Elegans) 2

External Ids for FER1L4 Gene

Previous HGNC Symbols for FER1L4 Gene

  • C20orf124

Previous GeneCards Identifiers for FER1L4 Gene

  • GC20M033904
  • GC20M034814
  • GC20M034861
  • GC20M034862
  • GC20M033609
  • GC20M034146
  • GC20M030924

Summaries for FER1L4 Gene

GeneCards Summary for FER1L4 Gene

FER1L4 (Fer-1 Like Family Member 4, Pseudogene) is a Pseudogene.

Additional gene information for FER1L4 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FER1L4 Gene

Genomics for FER1L4 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for FER1L4 Gene

Promoters and enhancers for FER1L4 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH20I035606 Enhancer 0.7 ENCODE 550.8 +0.1 83 1.2 ESRRA NEUROD1 EBF1 ZBTB7B ZFHX2 CTBP1 EGR1 FOS EGR2 SMARCE1 FER1L4 DLGAP4 RPL37P1
GH20I035301 Enhancer 1.7 FANTOM5 Ensembl ENCODE dbSUPER 4.8 +301.6 301554 9 PKNOX1 MLX ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9 UQCC1 GDF5 MMP24OS EDEM2 MMP24 CEP250 MIR1289-1 CPNE1 EIF6 NCOA6
GH20I035324 Enhancer 1.4 Ensembl ENCODE dbSUPER 4.7 +280.0 279962 5.3 FOXA2 MLX ARID4B DMAP1 YY1 SLC30A9 ZNF143 FOS DEK SP5 UQCC1 FAM83C EIF6 FAM83C-AS1 MMP24OS EDEM2 GDF5OS MMP24 CPNE1 FER1L4
GH20I035611 Enhancer 0.7 ENCODE 0.8 -3.9 -3898 0.8 BCOR PKNOX1 CHD4 CTBP1 IKZF2 RUNX3 SMARCE1 CBFB NR2F1 CBFA2T3 FER1L4 SPAG4
GH20I035601 Promoter/Enhancer 1.4 Ensembl ENCODE 0.4 +6.0 6049 1 HDAC1 ELF3 ATF1 RB1 SIN3A DEAF1 ZBTB40 RAD21 ZNF143 ATF7 RBM12 CPNE1 NCOA6 FER1L4 RPL37P1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around FER1L4 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the FER1L4 gene promoter:

Genomic Locations for FER1L4 Gene

Genomic Locations for FER1L4 Gene
chr20:35,558,737-35,607,562
(GRCh38/hg38)
Size:
48,826 bases
Orientation:
Minus strand
chr20:34,146,507-34,195,484
(GRCh37/hg19)

Genomic View for FER1L4 Gene

Genes around FER1L4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FER1L4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FER1L4 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for FER1L4 Gene

Proteins for FER1L4 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for FER1L4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A9Z1Z3-FR1L4_HUMAN
    Recommended name:
    Fer-1-like protein 4
    Protein Accession:
    A9Z1Z3
    Secondary Accessions:
    • Q9GZQ9
    • Q9H646
    • Q9H8L7

    Protein attributes for FER1L4 Gene

    Size:
    1794 amino acids
    Molecular mass:
    200980 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14597.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FER1L4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FER1L4 Gene

Protein Expression for FER1L4 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for FER1L4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FER1L4 Gene

Domains & Families for FER1L4 Gene

Gene Families for FER1L4 Gene

HGNC:

Protein Domains for FER1L4 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FER1L4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A9Z1Z3

UniProtKB/Swiss-Prot:

FR1L4_HUMAN :
  • Belongs to the ferlin family.
Family:
  • Belongs to the ferlin family.
genes like me logo Genes that share domains with FER1L4: view

Function for FER1L4 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes From GWAS Catalog for FER1L4 Gene

Phenotypes for FER1L4 Gene

GenomeRNAi human phenotypes for FER1L4:
genes like me logo Genes that share phenotypes with FER1L4: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FER1L4 Gene

Localization for FER1L4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for FER1L4 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for FER1L4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with FER1L4: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for FER1L4 Gene

Pathways & Interactions for FER1L4 Gene

SuperPathways for FER1L4 Gene

PathCards logo More details on SuperPathways for FER1L4
No Data Available

Interacting Proteins for FER1L4 Gene

Gene Ontology (GO) - Biological Process for FER1L4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FER1L4 Gene

Drugs & Compounds for FER1L4 Gene

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  1. Drug
No Compound Related Data Available

Transcripts for FER1L4 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for FER1L4 Gene

(6) Additional mRNA sequences :
(24) Selected AceView cDNA sequences:
(13) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FER1L4 Gene

Fer-1-like 4 (C. elegans) pseudogene:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for FER1L4 Gene

No ASD Table

Relevant External Links for FER1L4 Gene

GeneLoc Exon Structure for
FER1L4
ECgene alternative splicing isoforms for
FER1L4

Expression for FER1L4 Gene

Products:

  1. Primer
  2. Gene Expression Assay

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FER1L4 Gene

mRNA expression in normal human tissues for FER1L4 Gene
mRNA expression by GTEx for FER1L4 GenemRNA expression by BioGPS for FER1L4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FER1L4 Gene

This gene is overexpressed in Bladder (x12.0) and Stomach (x9.2).

Protein differential expression in normal tissues from HIPED for FER1L4 Gene

This gene is overexpressed in Monocytes (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FER1L4 Gene



Protein tissue co-expression partners for FER1L4 Gene

NURSA nuclear receptor signaling pathways regulating expression of FER1L4 Gene:

FER1L4

SOURCE GeneReport for Unigene cluster for FER1L4 Gene:

Hs.72222
genes like me logo Genes that share expression patterns with FER1L4: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FER1L4 Gene

Orthologs for FER1L4 Gene

Evolution for FER1L4 Gene

ENSEMBL:
Gene Tree for FER1L4 (if available)
TreeFam:
Gene Tree for FER1L4 (if available)

No data available for Orthologs for FER1L4 Gene

Paralogs for FER1L4 Gene

(3) SIMAP similar genes for FER1L4 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FER1L4: view

No data available for Paralogs for FER1L4 Gene

Variants for FER1L4 Gene

Products:

  1. SNP Genotyping and Copy Number Assay

Sequence variations from dbSNP and Humsavar for FER1L4 Gene

SNP ID Clin Chr 20 pos Variation AA Info Type
rs1000015631 -- 35,576,566(-) G/T intron_variant
rs1000070139 -- 35,591,855(-) A/G intron_variant
rs1000071362 -- 35,576,291(-) G/T intron_variant
rs1000090891 -- 35,575,451(-) G/A intron_variant
rs1000196706 -- 35,568,894(-) G/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for FER1L4 Gene

Variant ID Type Subtype PubMed ID
dgv698n67 CNV loss 20364138
esv2664066 CNV deletion 23128226
esv2722366 CNV deletion 23290073
esv3645716 CNV loss 21293372
nsv178794 CNV deletion 16902084
nsv517785 CNV loss 19592680
nsv526188 CNV gain 19592680
nsv526796 CNV loss 19592680

Additional Variant Information for FER1L4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FER1L4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for FER1L4 Gene

Disorders for FER1L4 Gene

Additional Disease Information for FER1L4

Genetic Association Database
(GAD)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for FER1L4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FER1L4 Gene

Publications for FER1L4 Gene

  1. Clinical significance of the low expression of FER1L4 in gastric cancer patients. (PMID: 24961353) Liu Z … Guo J (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014) 2 3 58
  2. Long non-coding RNA expression profile in human gastric cancer and its clinical significances. (PMID: 24063685) Song H … Guo J (Journal of translational medicine 2013) 2 3 58
  3. Biological, clinical and population relevance of 95 loci for blood lipids. (PMID: 20686565) Teslovich TM … Kathiresan S (Nature 2010) 3 44 58
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  5. LncRNA FER1L4 suppresses cancer cell proliferation and cycle by regulating PTEN expression in endometrial carcinoma. (PMID: 27381864) Qiao Q … Li H (Biochemical and biophysical research communications 2016) 3 58

Products for FER1L4 Gene

Sources for FER1L4 Gene

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