Aliases for FCSK Gene
External Ids for FCSK Gene
Previous HGNC Symbols for FCSK Gene
The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008]
GeneCards Summary for FCSK Gene
FCSK (Fucose Kinase) is a Protein Coding gene. Diseases associated with FCSK include Congenital Disorder Of Glycosylation With Defective Fucosylation 2 and Adhesions Of Uterus. Among its related pathways are Metabolism of proteins and Amino sugar and nucleotide sugar metabolism.
UniProtKB/Swiss-Prot Summary for FCSK Gene
Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides.