Aliases for FCER1G Gene
External Ids for FCER1G Gene
Previous GeneCards Identifiers for FCER1G Gene
The high affinity IgE receptor is a key molecule involved in allergic reactions. It is a tetramer composed of 1 alpha, 1 beta, and 2 gamma chains. The gamma chains are also subunits of other Fc receptors. [provided by RefSeq, Jul 2008]
GeneCards Summary for FCER1G Gene
FCER1G (Fc Fragment Of IgE Receptor Ig) is a Protein Coding gene. Diseases associated with FCER1G include Asthma and Mitochondrial Complex I Deficiency. Among its related pathways are Immune response Fc epsilon RI pathway and GPCR Pathway. Gene Ontology (GO) annotations related to this gene include transmembrane signaling receptor activity and IgE binding.
UniProtKB/Swiss-Prot for FCER1G Gene
Associates with a variety of FcR alpha chains to form a functional signaling complex. Regulates several aspects of the immune response. The gamma subunit has a critical role in allowing the IgE Fc receptor to reach the cell surface. Also involved in collagen-mediated platelet activation and in neutrophil activation mediated by integrin.