External Ids for FBXO16 Gene
Previous GeneCards Identifiers for FBXO16 Gene
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
GeneCards Summary for FBXO16 Gene
FBXO16 (F-Box Protein 16) is a Protein Coding gene. An important paralog of this gene is WDR49.
UniProtKB/Swiss-Prot Summary for FBXO16 Gene
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.