Aliases for FBXL6 Gene
External Ids for FBXL6 Gene
Previous GeneCards Identifiers for FBXL6 Gene
This gene encodes a member of a family of proteins that are characterized by an F-box motif. The encoded protein also contains leucine-rich repeats. F-box-containing proteins comprise one of the subunits of the SCF (SKP1-cullin-F-box) complex, which functions in phosphorylation-dependent ubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for FBXL6 Gene
FBXL6 (F-Box And Leucine Rich Repeat Protein 6) is a Protein Coding gene. Diseases associated with FBXL6 include Brown-Vialetto-Van Laere Syndrome 2 and Brown-Vialetto-Van Laere Syndrome. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is FBXL7.
UniProtKB/Swiss-Prot Summary for FBXL6 Gene
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.