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Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction ... See more...
Aliases for FBXL14 Gene
Aliases for FBXL14 Gene
External Ids for FBXL14 Gene
- HGNC: 28624
- Entrez Gene: 144699
- Ensembl: ENSG00000171823
- OMIM: 609081
- UniProtKB: Q8N1E6
Previous GeneCards Identifiers for FBXL14 Gene
- GC12M001546
- GC12M001547
- GC12M001549
- GC12M001675
Summaries for FBXL14 Gene
-
Members of the F-box protein family, such as FBXL14, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
GeneCards Summary for FBXL14 Gene
FBXL14 (F-Box And Leucine Rich Repeat Protein 14) is a Protein Coding gene. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is FBXL2.
UniProtKB/Swiss-Prot Summary for FBXL14 Gene
-
Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1.
Additional gene information for FBXL14 Gene
- HGNC(28624)
- Entrez Gene(144699)
- Ensembl(ENSG00000171823)
- OMIM(609081)
- UniProtKB(Q8N1E6)
- Open Targets Platform(ENSG00000171823)
- Search for FBXL14 at DataMed
- Search for FBXL14 at HumanCyc
No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FBXL14 Gene
Genomics for FBXL14 Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for FBXL14 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around FBXL14 on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FBXL14
- Top Transcription factor binding sites by QIAGEN in the FBXL14 gene promoter:
-
- AhR
- Arnt
- c-Ets-1
- C/EBPalpha
- MyoD
Genomic Locations for FBXL14 Gene
Genomic Locations for FBXL14 Gene
- chr12:1,559,641-1,594,581
- (GRCh38/hg38)
- Size:
- 34,941 bases
- Orientation:
- Minus strand
- chr12:1,675,159-1,703,331
- (GRCh37/hg19)
- Size:
- 28,173 bases
- Orientation:
- Minus strand
Genomic View for FBXL14 Gene
Genes around FBXL14 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12p13.33 by HGNC
- 12p13.33 by Entrez Gene
- 12p13.33 by Ensembl
FBXL14 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FBXL14 Gene
Proteins for FBXL14 Gene
-
Protein details for FBXL14 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8N1E6-FXL14_HUMAN
- Recommended name:
- F-box/LRR-repeat protein 14
- Protein Accession:
- Q8N1E6
Protein attributes for FBXL14 Gene
- Size:
- 418 amino acids
- Molecular mass:
- 45886 Da
- Quaternary structure:
-
- Part of a SCF (SKP1-cullin-F-box) ubiquitin-protein ligase complex. Interacts with SKP1 and CUL1 (By similarity). Interacts with SNAI1; the interaction requires the phosphorylation of the two serine residues in the substrate destruction motif D-S-G-X(2,3,4)-S.
Protein Expression for FBXL14 Gene
Post-translational modifications for FBXL14 Gene
Other Protein References for FBXL14 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Anti-FBXL14 monoclonal antibody
-
Custom Antibody ServicesOriGene Antibodies for FBXL14
- Novus Biologicals Antibodies for FBXL14
- Invitrogen Antibodies for FBXL14 (AFLGC-Fbxl14)
-
Biorbyt antibodies for FBXL14
Protein Products
-
OriGene Purified Proteins for FBXL14
- Search Origene for MassSpec and Protein Over-expression Lysates for FBXL14
- Origene Custom Protein Services for FBXL14
- antibodies-online: Show 4 available FBXL14 Proteins ranked by validation data
- Compare Top FBXL14 Proteins
-
Quality Products:
Assay Products
No data available for DME Specific Peptides for FBXL14 Gene
Domains & Families for FBXL14 Gene
Gene Families for FBXL14 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for FBXL14 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for FBXL14 Gene
- GenScript: Design optimal peptide antigens:
-
- F-box and leucine-rich repeat protein 14 (FXL14_HUMAN)
No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for FBXL14 Gene
Function for FBXL14 Gene
Molecular function for FBXL14 Gene
- UniProtKB/Swiss-Prot Function:
- Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin-protein ligase complexes. The SCF(FBXL14) complex acts by mediating ubiquitination and subsequent degradation of SNAI1.
- UniProtKB/Swiss-Prot Induction:
- Down-regulated by hypoxia.
Phenotypes From GWAS Catalog for FBXL14 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IDA | 19955572 |
| GO:0005515 | protein binding | IPI | 19955572 |
Phenotypes for FBXL14 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for FBXL14 - Select products 50% OFF >
- * FBXL14 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
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-
OriGene CRISPR knockouts for FBXL14
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FBXL14
-
Santa Cruz Biotechnology (SCBT) CRISPR for FBXL14
miRNA for FBXL14 Gene
- miRTarBase miRNAs that target FBXL14
-
- mmu-miR-136-5p (MIRT014916)
- hsa-miR-615-3p (MIRT040331)
- mmu-miR-669n (MIRT583558)
- mmu-miR-5104 (MIRT583559)
- mmu-miR-218-5p (MIRT583560)
- mmu-miR-335-3p (MIRT583561)
- mmu-miR-1b-5p (MIRT583562)
- mmu-miR-466c-3p (MIRT583563)
- mmu-miR-466p-3p (MIRT583564)
- mmu-miR-466b-3p (MIRT583565)
- mmu-miR-466o-3p (MIRT583566)
- mmu-miR-466m-3p (MIRT583567)
- mmu-miR-466f-3p (MIRT583568)
- mmu-miR-362-3p (MIRT583569)
- mmu-miR-329-3p (MIRT583570)
- mmu-miR-669f-3p (MIRT583571)
- mmu-miR-669m-3p (MIRT583572)
- mmu-let-7i-5p (MIRT583573)
- mmu-miR-1961 (MIRT583574)
- mmu-miR-98-5p (MIRT583575)
- mmu-let-7f-5p (MIRT583576)
- mmu-let-7e-5p (MIRT583577)
- mmu-let-7c-5p (MIRT583578)
- mmu-let-7d-5p (MIRT583579)
- mmu-let-7a-5p (MIRT583580)
- mmu-let-7g-5p (MIRT583581)
- mmu-let-7b-5p (MIRT583582)
- mmu-miR-3062-5p (MIRT583583)
- mmu-miR-201-5p (MIRT583584)
- mmu-miR-761 (MIRT590064)
- mmu-miR-214-3p (MIRT590065)
- mmu-miR-466n-3p (MIRT592719)
- mmu-miR-467g (MIRT592720)
- mmu-miR-466a-3p (MIRT592721)
- mmu-miR-466e-3p (MIRT592722)
- mmu-miR-466d-3p (MIRT592723)
- mmu-miR-297b-3p (MIRT592724)
- mmu-miR-466i-3p (MIRT592725)
- hsa-miR-4681 (MIRT746923)
- hsa-miR-5092 (MIRT749663)
- hsa-miR-4670-3p (MIRT770875)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FBXL14
- Browse OriGene Inhibitory RNA Products For FBXL14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FBXL14
Clone Products
- Applied Biological Materials (abm): Clones for FBXL14 - Select products 50% OFF >
- * FBXL14 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for FBXL14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FBXL14
Cell Line Products
-
Horizon Cell Lines for FBXL14
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FBXL14 Gene
Localization for FBXL14 Gene
Subcellular locations from UniProtKB/Swiss-Prot for FBXL14 Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 3 |
| extracellular | 2 |
| cytoskeleton | 1 |
| peroxisome | 1 |
| lysosome | 1 |
| golgi apparatus | 1 |
| mitochondrion | 0 |
- Cytosol (2)
- Golgi apparatus (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA,IDA | 19955572 |
| GO:0005829 | cytosol | TAS | -- |
| GO:0019005 | SCF ubiquitin ligase complex | IBA | 21873635 |
Pathways & Interactions for FBXL14 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Innate Immune System |
.61
|
|
Pathways by source for FBXL14 Gene
4 Reactome pathways for FBXL14 Gene
Interacting Proteins for FBXL14 Gene
Selected Interacting proteins:
Q8N1E6-FXL14_HUMAN
ENSP00000344855
for FBXL14 Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for FBXL14
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000209 | protein polyubiquitination | TAS | -- |
| GO:0006511 | ubiquitin-dependent protein catabolic process | IBA,IDA | 19955572 |
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | IBA | 21873635 |
| GO:0043687 | post-translational protein modification | TAS | -- |
No data available for SIGNOR curated interactions for FBXL14 Gene
Transcripts for FBXL14 Gene
mRNA/cDNA for FBXL14 Gene
- 1 REFSEQ mRNAs :
- 1 NCBI additional mRNA sequence :
- 2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000339235 2527 nts (view in UCSC)
- ENST00000543278 300 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for FBXL14 - Select products 50% OFF >
- * FBXL14 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for FBXL14
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FBXL14
-
Santa Cruz Biotechnology (SCBT) CRISPR for FBXL14
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FBXL14
- Browse OriGene Inhibitory RNA Products For FBXL14
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Clone Products
- Applied Biological Materials (abm): Clones for FBXL14 - Select products 50% OFF >
- * FBXL14 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for FBXL14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FBXL14
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||
| SP2: | - | - | |||||||||||
| SP3: | - |
Relevant External Links for FBXL14 Gene
- GeneLoc Exon Structure for
- FBXL14
Expression for FBXL14 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FBXL14 Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FBXL14
SOURCE GeneReport for Unigene cluster for FBXL14 Gene:
Hs.367956Evidence on tissue expression from TISSUES for FBXL14 Gene
- Lung(4.2)
Primer Products
-
OriGene qPCR primer pairs for FBXL14
-
OriGene qPCR primer pairs and template standards for FBXL14
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FBXL14 Gene
Orthologs for FBXL14 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Oppossum (Monodelphis domestica) |
Mammalia | FBXL14 31 |
|
OneToOne | |
| Chimpanzee (Pan troglodytes) |
Mammalia | FBXL14 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | FBXL14 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | FBXL14 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Fbxl14 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Fbxl14 30 |
|
||
| Chicken (Gallus gallus) |
Aves | FBXL14 30 |
|
||
| Lizard (Anolis carolinensis) |
Reptilia | FBXL14 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | fbxl14 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | fbxl14b 30 31 |
|
OneToOne | |
| ppab 30 |
|
||||
| Fruit Fly (Drosophila melanogaster) |
Insecta | ppa 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP010289 30 |
|
- Species where no ortholog for FBXL14 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Platypus (Ornithorhynchus anatinus)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for FBXL14 Gene
- ENSEMBL:
- Gene Tree for FBXL14 (if available)
- TreeFam:
- Gene Tree for FBXL14 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for FBXL14: view image
Paralogs for FBXL14 Gene
Variants for FBXL14 Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FBXL14 Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 778076 | Benign: not provided | 1,593,304(-) | G/A | SYNONYMOUS_VARIANT | |
| rs35571553 | - | p.Leu220Val |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2269n54 | CNV | loss | 21841781 |
| dgv2270n54 | CNV | loss | 21841781 |
| dgv2271n54 | CNV | gain | 21841781 |
| dgv2272n54 | CNV | gain+loss | 21841781 |
| dgv257n67 | CNV | gain | 20364138 |
| esv1091719 | CNV | insertion | 17803354 |
| esv1766777 | CNV | insertion | 17803354 |
| esv2658521 | CNV | deletion | 23128226 |
| esv2762959 | CNV | gain | 21179565 |
| esv27885 | CNV | loss | 19812545 |
| esv3628286 | CNV | loss | 21293372 |
| nsv1070500 | CNV | deletion | 25765185 |
| nsv470258 | CNV | gain | 18288195 |
| nsv556979 | CNV | loss | 21841781 |
| nsv556981 | CNV | gain+loss | 21841781 |
| nsv556986 | CNV | loss | 21841781 |
| nsv556990 | CNV | gain+loss | 21841781 |
| nsv556992 | CNV | gain | 21841781 |
| nsv556993 | CNV | loss | 21841781 |
Residual Variation Intolerance Score:
11.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.49;
10.61% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FBXL14 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- FBXL14
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FBXL14 Gene
Disorders for FBXL14 Gene
Additional Disease Information for FBXL14
No disorders were found for FBXL14 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FBXL14 Gene
Publications for FBXL14 Gene
- The hypoxia-controlled FBXL14 ubiquitin ligase targets SNAIL1 for proteasome degradation. (PMID: 19955572) Viñas-Castells R … Díaz VM (The Journal of biological chemistry 2010) 2 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- A reference map of the human binary protein interactome. (PMID: 32296183) Luck K … Calderwood MA (Nature 2020) 3
- VIRMA mediates preferential m6A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. (PMID: 29507755) Yue Y … Liu J (Cell discovery 2018) 3
- FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration. (PMID: 29348145) Fung E … D'Angiolella V (EMBO reports 2018) 3
ExternalLinks
Products for FBXL14 Gene
- Custom Antibody ServicesOriGene Antibodies for FBXL14
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for FBXL14
- Search Origene for MassSpec and Protein Over-expression Lysates for FBXL14
- Origene Custom Protein Services for FBXL14
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FBXL14
- Browse OriGene Inhibitory RNA Products For FBXL14
- OriGene qPCR primer pairs for FBXL14
- OriGene qPCR primer pairs and template standards for FBXL14
- OriGene CRISPR knockouts for FBXL14
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FBXL14
- Sino Biological Human cDNA Clone for FBXL14
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for FBXL14
- Novus Biologicals proteins and lysates for FBXL14
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Invitrogen Antibodies for FBXL14 (AFLGC-Fbxl14)
- VectorBuilder Custom and pre-made DNA vectors for FBXL14 (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for FBXL14 (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for FBXL14 (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for FBXL14 CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for FBXL14
- antibodies-online: Show 11 available FBXL14 Antibodies ranked by validation data
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- antibodies-online: Show 13 available FBXL14 Elisa Kits ranked by validation data
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- antibodies-online: Show 4 available FBXL14 Proteins ranked by validation data
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- Quality Products:
- Horizon Cell Lines for FBXL14
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FBXL14
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FBXL14
- Search GeneCopoeia for miRNA 3'UTR Target clone products for FBXL14
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FBXL14
- Biorbyt antibodies for FBXL14
Sources for FBXL14 Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
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