Aliases for FBXL13 Gene
External Ids for FBXL13 Gene
Previous GeneCards Identifiers for FBXL13 Gene
Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]
GeneCards Summary for FBXL13 Gene
FBXL13 (F-Box And Leucine Rich Repeat Protein 13) is a Protein Coding gene. Diseases associated with FBXL13 include Myeloid Tumor Suppressor. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is FBXL2.
UniProtKB/Swiss-Prot for FBXL13 Gene
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.