Aliases for FBP2 Gene
External Ids for FBP2 Gene
Previous GeneCards Identifiers for FBP2 Gene
This gene encodes a gluconeogenesis regulatory enzyme which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. [provided by RefSeq, Jul 2008]
GeneCards Summary for FBP2 Gene
FBP2 (Fructose-Bisphosphatase 2) is a Protein Coding gene. Diseases associated with FBP2 include Fructose-1,6-Bisphosphatase Deficiency and Glycogen Storage Disease. Among its related pathways are Glucose metabolism and Fructose and mannose metabolism. Gene Ontology (GO) annotations related to this gene include phosphoric ester hydrolase activity and fructose 1,6-bisphosphate 1-phosphatase activity. An important paralog of this gene is FBP1.
UniProtKB/Swiss-Prot Summary for FBP2 Gene
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.