Aliases for FAT2 Gene
External Ids for FAT2 Gene
Previous GeneCards Identifiers for FAT2 Gene
This gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development. [provided by RefSeq, Jul 2008]
GeneCards Summary for FAT2 Gene
FAT2 (FAT Atypical Cadherin 2) is a Protein Coding gene. Diseases associated with FAT2 include Spinocerebellar Ataxia 45 and Spinal Canal And Spinal Cord Meningioma. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is FAT1.
UniProtKB/Swiss-Prot for FAT2 Gene
Plays a role in the migration of epidermal cells. May modulate the extracellular space surronding parallel fibers of cerebellar during development (By similarity).