Aliases for FARSB Gene
External Ids for FARSB Gene
Previous HGNC Symbols for FARSB Gene
Previous GeneCards Identifiers for FARSB Gene
This gene encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for FARSB Gene
FARSB (Phenylalanyl-TRNA Synthetase Subunit Beta) is a Protein Coding gene. Diseases associated with FARSB include Neurodevelopmental Disorder With Brain, Liver, And Lung Abnormalities and Rigid Spine Muscular Dystrophy 1. Among its related pathways are tRNA Aminoacylation and Amino Acid metabolism. Gene Ontology (GO) annotations related to this gene include RNA binding and magnesium ion binding. An important paralog of this gene is LRRC47.