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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manne... See more...
Aliases for FARSA Gene
Aliases for FARSA Gene
External Ids for FARSA Gene
- HGNC: 3592
- Entrez Gene: 2193
- Ensembl: ENSG00000179115
- OMIM: 602918
- UniProtKB: Q9Y285
Previous HGNC Symbols for FARSA Gene
- FARSL
- FARSLA
Previous GeneCards Identifiers for FARSA Gene
- GC19M012895
- GC19M013033
- GC19M012605
Summaries for FARSA Gene
-
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. This gene encodes a product which is similar to the catalytic subunit of prokaryotic and Saccharomyces cerevisiae phenylalanyl-tRNA synthetases (PheRS). This gene product has been shown to be expressed in a tumor-selective and cell cycle stage- and differentiation-dependent manner, the first member of the tRNA synthetase gene family shown to exhibit this type of regulated expression [provided by RefSeq, Jul 2008]
GeneCards Summary for FARSA Gene
FARSA (Phenylalanyl-TRNA Synthetase Subunit Alpha) is a Protein Coding gene. Diseases associated with FARSA include B-Lymphoblastic Leukemia/Lymphoma With Hypodiploidy and B-Lymphoblastic Leukemia/Lymphoma With Hyperdiploidy. Among its related pathways are tRNA Aminoacylation and Gene Expression. Gene Ontology (GO) annotations related to this gene include tRNA binding. An important paralog of this gene is FARS2.
Additional gene information for FARSA Gene
- HGNC(3592)
- Entrez Gene(2193)
- Ensembl(ENSG00000179115)
- OMIM(602918)
- UniProtKB(Q9Y285)
- Open Targets Platform(ENSG00000179115)
- Search for FARSA at DataMed
- Search for FARSA at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for FARSA Gene
Genomics for FARSA Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for FARSA Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around FARSA on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for FARSA
- Top Transcription factor binding sites by QIAGEN in the FARSA gene promoter:
-
- ATF-2
- c-Jun
- CUTL1
- NF-kappaB1
- Nkx2-5
- p53
Genomic Locations for FARSA Gene
Genomic Locations for FARSA Gene
- chr19:12,922,479-12,934,037
- (GRCh38/hg38)
- Size:
- 11,559 bases
- Orientation:
- Minus strand
- chr19:13,033,284-13,044,851
- (GRCh37/hg19)
- Size:
- 11,568 bases
- Orientation:
- Minus strand
Genomic View for FARSA Gene
Genes around FARSA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19p13.13 by HGNC
- 19p13.13 by Entrez Gene
- 19p13.13 by Ensembl
FARSA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for FARSA Gene
Proteins for FARSA Gene
-
Protein details for FARSA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9Y285-SYFA_HUMAN
- Recommended name:
- Phenylalanine--tRNA ligase alpha subunit
- Protein Accession:
- Q9Y285
- B4E363
- Q9NSD8
- Q9Y4W8
Protein attributes for FARSA Gene
- Size:
- 508 amino acids
- Molecular mass:
- 57564 Da
- Quaternary structure:
-
- Heterotetramer; dimer of two heterodimers formed by FARSA and FARSB.
- SequenceCaution:
-
- Sequence=AAB51175.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for FARSA Gene
Selected DME Specific Peptides for FARSA Gene
- Q9Y285:
-
- FWNFDAL
- IFLEMGF
- GGYGSQGYKY
- KWVEVGNSG
- THLAEFHQ
- KNLLRTHTT
- VIAWGLSLERPTMIKYGINNIR
- MGFTEMP
- IDRVFRNE
- NIRELVGHKVNLQMVYDSP
- YNPYTEPS
- GSHEARVF
- VGFSKAM
Post-translational modifications for FARSA Gene
Other Protein References for FARSA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Creative Diagnostics Mouse anti-Human FARSA polyclonal antibody
- Creative Biolabs Recombinant Mouse Anti-Human FARSA Antibody
-
Custom Antibody ServicesOriGene Antibodies for FARSA
- Novus Biologicals Antibodies for FARSA
- Invitrogen Antibodies for FARSA (AFLGC-FARSA)
-
Biorbyt antibodies for FARSA
-
Santa Cruz Biotechnology (SCBT) Antibodies for FARSA
- Sino Biological Antibodies for FARSA
Protein Products
-
OriGene Purified Proteins for FARSA
- Search Origene for MassSpec and Protein Over-expression Lysates for FARSA
- Origene Custom Protein Services for FARSA
- antibodies-online: Show 7 available FARSA Proteins ranked by validation data
- Compare Top FARSA Proteins
-
Quality Products:
-
Signalway Proteins for FARSA
-
Abcam proteins for FARSA
Domains & Families for FARSA Gene
Gene Families for FARSA Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Enzymes
- Predicted intracellular proteins
Protein Domains for FARSA Gene
- InterPro:
- Blocks:
-
- Phenylalanyl-tRNA synthetase, class IIc
- Helix-turn-helix, type 11
- ProtoNet:
Suggested Antigen Peptide Sequences for FARSA Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ50378, highly similar to Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (B4E363_HUMAN)
- cDNA FLJ34774 fis, clone NT2NE2003309, highly similar to Phenylalanyl-tRNA synthetase alpha chain (EC 6.1.1.20) (Q6IBR2_HUMAN)
- Phenylalanine--tRNA ligase alpha chain (SYFA_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q9Y285UniProtKB/Swiss-Prot:
SYFA_HUMAN :- Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
- Family:
-
- Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily.
Function for FARSA Gene
Molecular function for FARSA Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Reaction=ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe); Xref=Rhea:RHEA:19413, Rhea:RHEA-COMP:9668, Rhea:RHEA-COMP:9699, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:58095, ChEBI:CHEBI:78442, ChEBI:CHEBI:78531, ChEBI:CHEBI:456215; EC=6.1.1.20; Evidence={ECO:0000269|PubMed:20223217};.
Enzyme Numbers (IUBMB) for FARSA Gene
Phenotypes From GWAS Catalog for FARSA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000049 | tRNA binding | IEA | -- |
| GO:0000166 | nucleotide binding | IEA | -- |
| GO:0003723 | RNA binding | HDA | 22681889 |
| GO:0004812 | aminoacyl-tRNA ligase activity | IEA | -- |
| GO:0004826 | phenylalanine-tRNA ligase activity | IEA,IDA | 20223217 |
Phenotypes for FARSA Gene
- MGI mutant phenotypes for FARSA:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for FARSA:
Animal Models for FARSA Gene
- MGI Knock Outs for FARSA:
-
- Farsa Farsa<tm2a(EUCOMM)Wtsi>
Animal Model Products
-
Taconic Biosciences Mouse Models for FARSA
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for FARSA - Select products 50% OFF >
- * FARSA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for FARSA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FARSA
-
Santa Cruz Biotechnology (SCBT) CRISPR for FARSA
miRNA for FARSA Gene
- miRTarBase miRNAs that target FARSA
-
- hsa-miR-503-5p (MIRT041106)
- hsa-miR-484 (MIRT041766)
- hsa-miR-221-3p (MIRT046922)
- hsa-let-7a-5p (MIRT052471)
- hsa-miR-4298 (MIRT451383)
- hsa-miR-1302 (MIRT451384)
- hsa-miR-4472 (MIRT451385)
- hsa-miR-4447 (MIRT451386)
- hsa-miR-6848-5p (MIRT451387)
- hsa-miR-92a-2-5p (MIRT451388)
- hsa-miR-6846-5p (MIRT451389)
- hsa-miR-4697-5p (MIRT451390)
- hsa-miR-4488 (MIRT451391)
- hsa-miR-1237-5p (MIRT451392)
- hsa-miR-185-3p (MIRT451393)
- hsa-miR-762 (MIRT451394)
- hsa-miR-5001-5p (MIRT451395)
- hsa-miR-4498 (MIRT451396)
- hsa-miR-4492 (MIRT451397)
- hsa-miR-6739-5p (MIRT451398)
- hsa-miR-6733-5p (MIRT451399)
- hsa-miR-3153 (MIRT451400)
- hsa-miR-4668-5p (MIRT451401)
- hsa-miR-6876-5p (MIRT451402)
- hsa-miR-4476 (MIRT451403)
- hsa-miR-6859-5p (MIRT451404)
- hsa-miR-3916 (MIRT451405)
- hsa-miR-3125 (MIRT451406)
- hsa-miR-552-3p (MIRT451407)
- hsa-miR-583 (MIRT451408)
- hsa-miR-27b-3p (MIRT727685)
- hsa-miR-27a-3p (MIRT727686)
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FARSA
- Browse OriGene Inhibitory RNA Products For FARSA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FARSA
Clone Products
- Applied Biological Materials (abm): Clones for FARSA - Select products 50% OFF >
- * FARSA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for FARSA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FARSA
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for FARSA Gene
Localization for FARSA Gene
Subcellular locations from UniProtKB/Swiss-Prot for FARSA Gene
- Cytoplasm.
| Compartment | Confidence |
|---|---|
| cytosol | 4 |
| nucleus | 3 |
| plasma membrane | 1 |
| extracellular | 1 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| peroxisome | 1 |
| endoplasmic reticulum | 1 |
| golgi apparatus | 1 |
- Cytosol (3)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA,IBA | 21873635 |
| GO:0005829 | cytosol | TAS | -- |
| GO:0009328 | phenylalanine-tRNA ligase complex | IBA,IDA | 20223217 |
| GO:0016020 | membrane | HDA | 19946888 |
Pathways & Interactions for FARSA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | tRNA Aminoacylation | ||
| 2 | Gene Expression |
.48
|
|
Pathways by source for FARSA Gene
3 Reactome pathways for FARSA Gene
1 KEGG pathway for FARSA Gene
Interacting Proteins for FARSA Gene
Selected Interacting proteins:
Q9Y285-SYFA_HUMAN
ENSP00000320309
for FARSA Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for FARSA
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006412 | translation | IEA | -- |
| GO:0006418 | tRNA aminoacylation for protein translation | TAS | -- |
| GO:0006432 | phenylalanyl-tRNA aminoacylation | IEA,IDA | 20223217 |
| GO:0043039 | tRNA aminoacylation | IEA | -- |
| GO:0051290 | protein heterotetramerization | IDA | 20223217 |
No data available for SIGNOR curated interactions for FARSA Gene
Drugs & Compounds for FARSA Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Phenylalanine | Approved, Investigational | Nutra | Target | 256 | ||
| Phosphoric acid | Approved | Pharma | 0 | |||
| Adenosine monophosphate | Approved, Investigational | Nutra | 0 | |||
| ATP | Investigational | Nutra | Agonist, Activator, Partial agonist, Antagonist, Full agonist, Gating inhibitor, Pore Blocker, Potentiation | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| pyrophosphate |
|
14000-31-8 |
|
Transcripts for FARSA Gene
mRNA/cDNA for FARSA Gene
- 1 REFSEQ mRNAs :
- 12 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000314606 1811 nts (view in UCSC)
- ENST00000423140 1720 nts (view in UCSC)
- ENST00000586146 1707 nts (view in UCSC)
- ENST00000586280 803 nts (view in UCSC)
- ENST00000587488 514 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for FARSA - Select products 50% OFF >
- * FARSA CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for FARSA
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FARSA
-
Santa Cruz Biotechnology (SCBT) CRISPR for FARSA
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FARSA
- Browse OriGene Inhibitory RNA Products For FARSA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FARSA
Clone Products
- Applied Biological Materials (abm): Clones for FARSA - Select products 50% OFF >
- * FARSA as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for FARSA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FARSA
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||||||||||||||||||||
| SP2: | |||||||||||||||||||||||||||||||||||
| SP3: | |||||||||||||||||||||||||||||||||||
| SP4: |
Relevant External Links for FARSA Gene
- GeneLoc Exon Structure for
- FARSA
Expression for FARSA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
This gene is overexpressed in Lymph node (7.7).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for FARSA Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for FARSA
SOURCE GeneReport for Unigene cluster for FARSA Gene:
Hs.23111Evidence on tissue expression from TISSUES for FARSA Gene
- Nervous system(4.6)
- Lung(4.5)
- Blood(4.4)
- Skin(3.5)
- Intestine(3)
- Muscle(2.6)
- Liver(2.5)
- Eye(2.3)
- Heart(2.2)
- Kidney(2.1)
Primer Products
-
OriGene qPCR primer pairs for FARSA
-
OriGene qPCR primer pairs and template standards for FARSA
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for FARSA Gene
Orthologs for FARSA Gene
This gene was present in the common ancestor of eukaryotes.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | FARSA 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | FARSA 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | FARSA 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | FARSA 30 31 |
|
OneToOne | |
| Oppossum (Monodelphis domestica) |
Mammalia | FARSA 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Farsa 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Farsa 30 |
|
||
| Chicken (Gallus gallus) |
Aves | FARSA 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | FARSA 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | farsa 30 |
|
||
| Str.3839 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | farsl-prov 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | farsa 30 31 |
|
OneToOne | |
| wufj21a11 30 |
|
||||
| Rainbow Trout (Oncorhynchus mykiss) |
Actinopterygii | Omy.10382 30 |
|
||
| Fruit Fly (Drosophila melanogaster) |
Insecta | CG2263 30 31 |
|
OneToOne | |
| African malaria mosquito (Anopheles gambiae) |
Insecta | AgaP_AGAP002653 30 |
|
||
| Worm (Caenorhabditis elegans) |
Secernentea | fars-1 30 31 |
|
OneToOne | |
| A. gosspyii yeast (Eremothecium gossypii) |
Saccharomycetes | AGOS_AFR516W 30 |
|
||
| Baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | FRS2 30 31 33 |
|
OneToOne | |
| K. Lactis Yeast (Kluyveromyces lactis) |
Saccharomycetes | KLLA0F25234g 30 |
|
||
| Thale Cress (Arabidopsis thaliana) |
eudicotyledons | AT4G39280 30 |
|
||
| Soybean (Glycine max) |
eudicotyledons | Gma.12602 30 |
|
||
| Rice (Oryza sativa) |
Liliopsida | Os10g0400800 30 |
|
||
| Os.3191 30 |
|
||||
| Barley (Hordeum vulgare) |
Liliopsida | Hv.10634 30 |
|
||
| Wheat (Triticum aestivum) |
Liliopsida | Ta.1529 30 |
|
||
| Corn (Zea mays) |
Liliopsida | Zm.5623 30 |
|
||
| Sea Squirt (Ciona savignyi) |
Ascidiacea | CSA.1858 31 |
|
OneToOne | |
| Bread mold (Neurospora crassa) |
Ascomycetes | NCU05095 30 |
|
||
| Fission Yeast (Schizosaccharomyces pombe) |
Schizosaccharomycetes | frs2 30 |
|
||
| Sea Vase (Ciona intestinalis) |
Ascidiacea | Cin.11498 30 |
|
- Species where no ortholog for FARSA was found in the sources mined by GeneCards:
-
- Actinobacteria (Mycobacterium tuberculosis)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Beta proteobacteria (Neisseria meningitidis)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
Evolution for FARSA Gene
- ENSEMBL:
- Gene Tree for FARSA (if available)
- TreeFam:
- Gene Tree for FARSA (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for FARSA: view image
Paralogs for FARSA Gene
Variants for FARSA Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for FARSA Gene
| SNP ID | Clinical significance and condition | Chr 19 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 871679 | Uncertain Significance: not provided | 12,924,918(-) | G/A | MISSENSE_VARIANT | |
| rs35087277 | - | p.Gln341Arg |
Residual Variation Intolerance Score:
24.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.69;
46.23% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for FARSA Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FARSA Gene
Disorders for FARSA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| b-lymphoblastic leukemia/lymphoma with hypodiploidy |
|
|
| b-lymphoblastic leukemia/lymphoma with hyperdiploidy |
|
|
| autosomal recessive cerebellar ataxia |
|
|
| fetal akinesia deformation sequence 1 |
|
|
Search FARSA in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for FARSA
No data available for UniProtKB/Swiss-Prot and Genatlas for FARSA Gene
Publications for FARSA Gene
- Expression of a gene encoding a tRNA synthetase-like protein is enhanced in tumorigenic human myeloid leukemia cells and is cell cycle stage- and differentiation-dependent. (PMID: 9177188) Sen S … White RA (Proceedings of the National Academy of Sciences of the United States of America 1997) 2 3 4 23
- Structure of human cytosolic phenylalanyl-tRNA synthetase: evidence for kingdom-specific design of the active sites and tRNA binding patterns. (PMID: 20223217) Finarov I … Safro MG (Structure (London, England : 1993) 2010) 3 4
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
- The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 3 4
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4
ExternalLinks
Products for FARSA Gene
- Custom Antibody ServicesOriGene Antibodies for FARSA
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- Custom Assay Services
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- Search Origene for MassSpec and Protein Over-expression Lysates for FARSA
- Origene Custom Protein Services for FARSA
- Origene shrna, sirna, and RNAi products in human, mouse, rat for FARSA
- Browse OriGene Inhibitory RNA Products For FARSA
- OriGene qPCR primer pairs for FARSA
- OriGene qPCR primer pairs and template standards for FARSA
- OriGene CRISPR knockouts for FARSA
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For FARSA
- Sino Biological Human cDNA Clone for FARSA
- Browse Sino Biological Recombinant Proteins
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- Sino Biological Antibodies for FARSA
- Browse Sino Biological Assays
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for FARSA
- Novus Biologicals proteins and lysates for FARSA
- Browse Antibodies
- Browse Peptides and Proteins
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- Browse ELISA Kits
- Abcam proteins for FARSA
- Find your target
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- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- Taconic Biosciences Mouse Models for FARSA
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for FARSA (AFLGC-FARSA)
- VectorBuilder Custom and pre-made DNA vectors for FARSA (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for FARSA (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for FARSA (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for FARSA CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for FARSA
- antibodies-online: Show 28 available FARSA Antibodies ranked by validation data
- Compare Top FARSA Antibodies
- antibodies-online: Search results for available FARSA related products ranked by validation data
- antibodies-online: Show 7 available FARSA Proteins ranked by validation data
- Compare Top FARSA Proteins
- Quality Products:
- Santa Cruz Biotechnology (SCBT) Antibodies for FARSA
- Search Santa Cruz Biotechnology (SCBT) for FARSA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for FARSA
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for FARSA
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for FARSA
- Search GeneCopoeia for miRNA 3'UTR Target clone products for FARSA
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for FARSA
- Biorbyt antibodies for FARSA
- Signalway Proteins for FARSA
Sources for FARSA Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB